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South Carolina: below-average open trial sites
591 of 1,706 in-state trials are recruiting (35%); below the 37% national average by 2 percentage points.
According to ClinicalTrials.gov-derived indexes, South Carolina sits in the lower half of US states by in-state trial count (#32 of 52 states by registered in-state trial count).
South Carolina: 1,706 US clinical trials with in-state sites, 591 recruiting.
South Carolina has 1,706 registered US clinical trials with a study site in-state, 591 of them currently recruiting (below the 37% national average by 2 percentage points). 320 of these trials are in Phase 3 (late-stage) and 408 in Phase 2. The most frequently studied condition in South Carolina is Stroke, with 32 linked trials.
Lower-half South Carolina archive
South Carolina open-enrollment share is 35% (p78 of states with sites; national baseline 37%). Treat this page as a compact local index (mid-volume · high-open), then jump to recruiting trials or methodology rather than expecting hub-scale coverage.
Below-average open enrollment
South Carolina still shows 591 recruiting of 1,706 in-state trials (35% open), but below the 37% national average by 2 percentage points, so archived statuses weigh heavier than the national baseline.
- 35%
- open (below national share)
- 591
- still recruiting despite cool share
- 408
- Phase 2 rows in this footprint
- 32
- top: Stroke
Recruiting share is below the 37% national average by 2 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
South Carolina vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
1,706 Top 62% more indexed trials than 38% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for South Carolina on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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South Carolina open-enrollment share sits below the national baseline.
591 of 1,706 in-state trials (34.6%) are recruiting, against 37% nationally (-2.4 percentage points). Counts include every study with at least one recorded site in the state.
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Charleston dominates South Carolina's trial geography.
Charleston lists 878 of 1,706 in-state trials (51.5%) across 245 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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Stroke is the most-studied condition in South Carolina.
32 of 1,706 in-state trials (1.9%) list Stroke. That is a local concentration figure, not a national disease ranking.
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One sponsor accounts for a large share of South Carolina trials.
Medical University of South Carolina appears on 253 of 1,706 in-state trials (14.8%). Sponsor identity is as filed on ClinicalTrials.gov.
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838 South Carolina trials carry a completed status.
838 of 1,706 (49.1%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 838 |
| Recruiting | 591 |
| Active | 277 |
By Phase
| Phase | Trial count |
|---|---|
| NA | 490 |
| Phase 2 | 408 |
| Phase 3 | 320 |
| Phase 1 | 201 |
| Phase 4 | 74 |
| Early Phase 1 | 23 |
Top Conditions
Top Sponsors
Where trials run in South Carolina
Charleston carries 878 of South Carolina's 1,706 indexed trials (51%) across 245 named sites, ahead of Greenville at 253. 8 cities clear five listed trials, together naming 631 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Charleston | 878 | 245 |
| Greenville | 253 | 129 |
| Columbia | 181 | 90 |
| Spartanburg | 110 | 54 |
| Myrtle Beach | 85 | 34 |
| Mt. Pleasant | 58 | 27 |
| North Charleston | 54 | 34 |
| West Columbia | 34 | 18 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Open-share high
South Carolina open-enrollment share is 35% (p78 of states with sites; national baseline 37%).
South Carolina: open share sits in the high tercile of states
Sites spread across 8 cities with five or more listed trials, led by Charleston (878, 51% of the state total) and Greenville (253), together naming 631 distinct research locations.
Phase mix: 320 Phase 3 vs 408 Phase 2 (balanced across stages).
Top condition: Stroke (32 trials); top sponsor Medical University of South Carolina (253).
mid-volume · high-open figures (1,706 trials · 35% open) describe registry geography under the open-share high read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near South Carolina on open-enrollment share
Cross-state peers under the open-share high read (mid-volume · high-open), not the same-state browse list.
Similar mid-volume peers (± open share)
Similar high-open peers (± trial volume)
- New York · 35% recruiting · 10,554 trials
- Michigan · 34% recruiting · 4,790 trials
- Oklahoma · 34% recruiting · 1,061 trials
- Rhode Island · 34% recruiting · 753 trials
- Pennsylvania · 34% recruiting · 6,946 trials