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South Carolina: below-average open trial sites
591 of 1,706 in-state trials are recruiting (35%); below the 37% national average by 2 percentage points.
According to ClinicalTrials.gov-derived indexes, South Carolina sits in the lower half of US states by in-state trial count (#32 of 52 states by registered in-state trial count).
South Carolina: 1,706 US clinical trials with in-state sites, 591 recruiting.
South Carolina has 1,706 registered US clinical trials with a study site in-state, 591 of them currently recruiting (below the 37% national average by 2 percentage points). 320 of these trials are in Phase 3 (late-stage) and 408 in Phase 2. The most frequently studied condition in South Carolina is Stroke, with 32 linked trials.
South Carolina sits in the lower half by volume
South Carolina open-enrollment share is 35% (p78 of states with sites; national baseline 37%). Read it as a compact, local-scale index (mid-volume · high-open): the recruiting trials or methodology pages are the better stop for hub-scale coverage.
Below-average open enrollment
South Carolina still shows 591 recruiting of 1,706 in-state trials (35% open), but below the 37% national average by 2 percentage points, so archived statuses weigh heavier than the national baseline.
- 35%
- open (below national share)
- 591
- still recruiting despite cool share
- 408
- Phase 2 rows in this footprint
- 32
- top: Stroke
Recruiting share is below the 37% national average by 2 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
South Carolina vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
1,706 Top 62% more indexed trials than 38% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for South Carolina on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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South Carolina open-enrollment share sits below the national baseline.
591 of 1,706 in-state trials (34.6%) are recruiting, against 37% nationally (-2.4 percentage points). Counts include every study with at least one recorded site in the state.
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Charleston dominates South Carolina's trial geography.
Charleston lists 878 of 1,706 in-state trials (51.5%) across 245 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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Stroke is the most-studied condition in South Carolina.
32 of 1,706 in-state trials (1.9%) list Stroke. That is a local concentration figure, not a national disease ranking.
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One sponsor accounts for a large share of South Carolina trials.
Medical University of South Carolina appears on 253 of 1,706 in-state trials (14.8%). Sponsor identity is as filed on ClinicalTrials.gov.
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838 South Carolina trials carry a completed status.
838 of 1,706 (49.1%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 838 |
| Recruiting | 591 |
| Active | 277 |
By Phase
| Phase | Trial count |
|---|---|
| NA | 490 |
| Phase 2 | 408 |
| Phase 3 | 320 |
| Phase 1 | 201 |
| Phase 4 | 74 |
| Early Phase 1 | 23 |
Top Conditions
Top Sponsors
Where trials run in South Carolina
Charleston carries 878 of South Carolina's 1,706 indexed trials (51%) across 245 named sites, ahead of Greenville at 253. 8 cities clear five listed trials, together naming 631 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Charleston | 878 | 245 |
| Greenville | 253 | 129 |
| Columbia | 181 | 90 |
| Spartanburg | 110 | 54 |
| Myrtle Beach | 85 | 34 |
| Mt. Pleasant | 58 | 27 |
| North Charleston | 54 | 34 |
| West Columbia | 34 | 18 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Open-share high
South Carolina open-enrollment share is 35% (p78 of states with sites; national baseline 37%).
South Carolina: open share sits in the high tercile of states
Sites spread across 8 cities with five or more listed trials, led by Charleston (878, 51% of the state total) and Greenville (253), together naming 631 distinct research locations.
Phase mix: 320 Phase 3 vs 408 Phase 2 (balanced across stages).
Top condition: Stroke (32 trials); top sponsor Medical University of South Carolina (253).
mid-volume · high-open figures (1,706 trials · 35% open) describe registry geography under the open-share high read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near South Carolina on open-enrollment share
Cross-state peers under the open-share high read (mid-volume · high-open), not the same-state browse list.
Similar mid-volume peers (± open share)
Similar high-open peers (± trial volume)
- New York · 35% recruiting · 10,554 trials
- Michigan · 34% recruiting · 4,790 trials
- Oklahoma · 34% recruiting · 1,061 trials
- Rhode Island · 34% recruiting · 753 trials
- Pennsylvania · 34% recruiting · 6,946 trials