Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05065450 · ClinicalTrials.gov registry record · NA

Amygdala Memory Enhancement

A NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, sponsored by Washington University School of Medicine.

Recruiting
Registry status
NA
Development phase
90
Enrollment target
1
Study location

NCT05065450: Recruiting NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, sponsored by Washington University School of Medicine.

NCT05065450 is a NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 90 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05065450, a NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.

Primary Outcome

Proportion of items (objects, associations, and scenes) accurately recalled during the delayed recall trial will be compared with and without BLAES for each participant in a within subject design. Subsets of items may be tested after durations up to a month after initial presentation.

Interventions

  • DEVICE Intracranial Stimulation

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2021-11-01
Est. Completion 2027-11-01
Phase NA

What NCT05065450 shows while recruiting

NCT05065450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (86% lower).

The record links to 6 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Intracranial Stimulation is the first listed.

NCT05065450 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT05065450 about?

NCT05065450 is a clinical study titled "Amygdala Memory Enhancement". The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.

What is the current status of trial NCT05065450?

This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2021-11-01. Estimated completion is 2027-11-01.

What conditions does trial NCT05065450 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Traumatic Brain Injury, Epilepsy, Cognitive Impairment, Brain Diseases.

What interventions are being tested in trial NCT05065450?

The interventions under investigation include: Intracranial Stimulation (DEVICE).

Who is sponsoring clinical trial NCT05065450?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05065450 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05065450's enrollment target sits among peer trials

90 120th of 262 higher than 141 of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02521311 · 90 participants · Phase 2

    Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

  • NCT02939573 · 90 participants · Phase 2

    A Randomized Multicenter Study for Isolated Skin Vasculitis

  • NCT03128879 · 90 participants · Phase 2

    Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL

  • NCT03184038 · 90 participants · NA

    Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05065450, the US trial registry maintained by the National Library of Medicine. NCT05065450 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.