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NCT05646732 · ClinicalTrials.gov registry record · NA
Targeting the Default Mode Network: A TMS-fMRI Study
A NA study of PTSD and Post Traumatic Stress Disorder, sponsored by Allyson Rosen.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05646732 is a NA study of PTSD and Post Traumatic Stress Disorder that is actively recruiting participants, run by Allyson Rosen. The registered enrollment target is 30 participants, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05646732, a NA study of PTSD and Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Allyson Rosen.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
In post-traumatic stress disorder (PTSD), intrusive, traumatic, autobiographical memories lead to anxiety symptoms. Recent work suggests a new repetitive pulse transcranial magnetic stimulation (rTMS) brain target that might bring relief. Since this proposed target is not well understood, the goal of the study is to use functional magnetic resonance imaging (fMRI) to identify the brain regions and networks that change with rTMS stimulation at this target area in PTSD patients. Ultimately, this would lead to a personalized approach to rTMS treatment of PTSD based on brain imaging that can be used in a future clinical trial. Participants will be asked to complete psychological testing and questionnaires as well as an initial MRI and two separate TMS-fMRI sessions. Total participation time across all visits is estimated to be five to six hours. Research participation will take place at VA Palo Alto as well as at Stanford University.
Conditions Studied
Interventions
- DEVICE TMS-fMRI
Study Locations (1)
California
- VA Palo Alto - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-08-02 |
| Est. Completion | 2025-01-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05646732
The ClinicalTrials.gov registry entry for NCT05646732 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (90% lower). The listed sponsor is Allyson Rosen, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with PTSD appearing as the primary indexed condition, and to 1 intervention - of which TMS-fMRI is the first listed.
NCT05646732 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05646732 about?
NCT05646732 is a clinical study titled "Targeting the Default Mode Network: A TMS-fMRI Study". In post-traumatic stress disorder (PTSD), intrusive, traumatic, autobiographical memories lead to anxiety symptoms. Recent work suggests a new repetitive pulse transcranial magnetic stimulation (rTMS) brain target that might bring relief. Since this proposed target is not well understood, the goal o...
What is the current status of trial NCT05646732?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2023-08-02. Estimated completion is 2025-01-31.
What conditions does trial NCT05646732 study?
This clinical trial studies the following conditions: PTSD, Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT05646732?
The interventions under investigation include: TMS-fMRI (DEVICE).
Who is sponsoring clinical trial NCT05646732?
This trial is sponsored by Allyson Rosen, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05646732 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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