Yale University
Trial Pipeline
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
NCT04355572
Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics
NCT06684613
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
NCT07273838
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
NCT07224087
Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1
NCT07457736
A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis
NCT07291180
Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels
NCT07282912
Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers
NCT07224204
Digital Mindfulness for Young Adults With Type 1 Diabetes
NCT07062887
Investigation of Lymph Node Biology in Kidney Cancer
NCT07038733
Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing
NCT07281014
Iadademstat + SBRT With Atezo in ES-SCLC
NCT07113691
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
NCT07040592
Off Treatment Urinary Copper Excretion in Wilson Disease, Pilot Study
NCT07301216
Non-invasive Venous Pressure Estimation
NCT07226479
Project Women's Insomnia Sleep Health Equity Study (WISHES)
NCT06348082
Saci Nivo Rela for TNBC
NCT06963905
Luspatercept + Darbepoetin in MDS
NCT07096297
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
NCT06917313
RCT of Cervical Ripening Double Ballon Catheter Prior to Dilation and Evacuation.
NCT07200115
Identification of Brain Injury Using Portable MRI
NCT07197918
Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma
NCT07048457
Shared Decision Making to Treat Or Prevent (STOP) HIV in Justice Populations (R33)
NCT07223398
New Mechanisms of Obesity
NCT06768827
Parent-Based Treatment for Adolescent Anxiety
NCT07219992
Hyperfractionated Dual Equivalent Fractionated Radiation Therapy
NCT06898905
SORE Study: Sitz Baths After Urogynecologic Reconstruction
NCT07215780
Lifestyle, Exercise, And Nutrition (LEAN) Trial on Pathologic Complete Response in TNBC
NCT07066189
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
NCT07228429
A Trial of Varenicline for E-cigarette Cessation
NCT07040566
Subcortical Arousal in Perceptual Awareness
NCT06934356
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
NCT06671015
Exploring Water-free Sodium Storage
NCT06872645
Circulating Tumor DNA
NCT06923527
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
NCT06834217
MDMA in Borderline Personality Disorder
NCT06683014
T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 Diabetes
NCT07059806
Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening
NCT07155252
AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
NCT07027488
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
NCT06070649
Nourishing Hope: The Impact of Nutrition in Cancer Treatment and Recovery in Maine
NCT07076004
Psychedelic Virtual Reality
NCT06581263
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
NCT06407427
Merck IIT: RRP Pembro and Lenvatinib
NCT04645602
Building and Sustaining Exercise Habits for Adults With Type 1 Diabetes
NCT06967701
Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy
NCT06953882
Pilot fMRI Studies of Aging-Related Effects of THC
NCT06647524
Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors
NCT07019259
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
NCT05932745
Trial of Trastuzumab Deruxtecan in Previously Treated HER2
NCT06750484
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
NCT06006143
Video-Based Pelvic Floor Muscle Therapy
NCT06689891
Acute Effects of THC in Older Adult
NCT06948136
Digoxin In NASH (CODIN)
NCT06588699
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
NCT06160284
Mechanistic Studies of Psilocybin in Headache Disorders
NCT06464367
Regulation of Brain Glucose Metabolism in Type 1 Diabetes
NCT05317455
rTMS as Add on Treatment for Substance Use Disorders
NCT06963476
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
NCT06999434
Change 4 Better (C4B)
NCT06963931
Portable Rapid Imaging for Medical Emergencies
NCT06930534
Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
NCT06609369
tDCS for Laryngeal Dystonia
NCT06830174
Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery
NCT06474754
Adaptive Decision Support for Addiction Treatment Master
NCT06799117
Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder
NCT06446765
Efficacy of Guselkumab in Treating Hailey Hailey Disease
NCT06651489
Effects of Enriched Parent-Infant Interaction on Health in Early Life
NCT06248125
Substance Misuse and Family Violence Treatment Fathers
NCT06650267
Measuring Brain Health Using Low-Field Portable MRI
NCT06533631
Opioid Use Disorder and Pain
NCT06800703
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
NCT06713616
Kick-Nic! Youth Quit Vaping App
NCT06662305
Stress and Pain in People Living With HIV
NCT06784908
HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
NCT06513819
fMRI and Opioid Abstinence
NCT06651333
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
NCT06624137
Standard Versus High Dose ED-Initiated Buprenorphine Induction
NCT06494904
Craving Network Neurofeedback
NCT06426693
Patient Controlled Administration of Liquid Acetaminophen
NCT06498713
Continuous Glucose Monitors (CGMs) for All: Studying the Impact of Expanding CGM Access
NCT06658067
Drinking, Acetate, and Stress
NCT06584448
PRIDE III Prison Interventions and HIV Prevention Collaboration
NCT06962033
Developing a Novel Human Laboratory Paradigm for AUD Medication Screening
NCT06489782
Oral Contraceptive Pill (OCP) Pharmacogenomics
NCT06334315
Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
NCT06172660
Combined THC and CBD for OUD and Chronic Pain
NCT06544291
Open-Label Psilocybin Study in Transdiagnostic Population
NCT06442423
MyChart Proxy Outreach to Parents (MyPOP)
NCT05989308
Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant with Neoadjuvant Therapy
NCT05989347
Longitudinal Neural Fingerprinting of Opioid-use Trajectories
NCT06207162
Study of Mogamulizumab With DA-EPOCH or CHOEP in Patients With Aggressive T-cell Lymphoma
NCT05996185
Speech Motor Learning and Retention (Aim 1)
NCT06467305
Speech Motor Learning and Retention (Aim 2)
NCT06491823
Speech Motor Learning and Retention (Master Protocol)
NCT06467292
M2VA Pain Care Pathway
NCT06526143
Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans
NCT06058702
Imaging Depression in Parkinson's Disease
NCT06402955
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
NCT06077240
Emergency Department-Initiated Medications for Alcohol Use Disorder
NCT05827159
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 223 |
| Phase 2 | 371 |
| Phase 3 | 18 |
| Phase 4 | 79 |
Therapeutic Areas
What the Pipeline for Yale University Shows
According to the ClinicalTrials.gov registry, Yale University is linked to 1,283 US clinical trials across every stage of research activity. Of those, 985 studies are currently recruiting — about 77% of the sponsor's indexed portfolio — and 243 are already marked complete, representing roughly 19% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Yale University reports 97 late-stage studies (Phase 3 and Phase 4 combined) and 594 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Yale University is Opioid Use Disorder with 16 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.