Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 1 of 30

RECRUITING NA

Abriendo Caminos: Engaging Latinos

NCT07529509

RECRUITING NA

Colorectal Cancer Screening Outreach

NCT07345676

RECRUITING NA

Evaluation of a Mobile App Program for Coping With Cancer

NCT06923501

RECRUITING NA

Music for Pain and Dementia

NCT07602283

RECRUITING NA

Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life

NCT07376655

RECRUITING NA

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

NCT07115030

RECRUITING NA

Skin Color Matching in Head and Neck Reconstructive Surgery

NCT07431099

RECRUITING Phase 3

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

NCT07332442

RECRUITING Phase 2

Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

NCT07029529

RECRUITING Phase 2

Long Term Evaluation of Scapular-inserted Contraceptive Implants

NCT07201402

RECRUITING Phase 2

CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs

NCT07172256

RECRUITING NA

Speech Motor Learning and Retention (Aim 3)

NCT06492252

RECRUITING NA

Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)

NCT04355572

RECRUITING NA

Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD)

NCT07525258

RECRUITING NA

PoRI Clinical Trial

NCT07407023

RECRUITING NA

Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics

NCT06684613

RECRUITING Phase 1

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

NCT07223983

RECRUITING Phase 2

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

NCT07273838

RECRUITING Phase 1

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087

RECRUITING Early Phase 1

Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1

NCT07457736

RECRUITING NA

A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis

NCT07291180

RECRUITING Phase 2

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

NCT07282912

RECRUITING NA

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

NCT07103902

RECRUITING NA

Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers

NCT07224204

RECRUITING NA

Digital Mindfulness for Young Adults With Type 1 Diabetes

NCT07062887

RECRUITING NA

Investigation of Lymph Node Biology in Kidney Cancer

NCT07038733

RECRUITING Phase 4

Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing

NCT07281014

RECRUITING Phase 1

Iadademstat + SBRT With Atezo in ES-SCLC

NCT07113691

RECRUITING NA

Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

NCT06847360

RECRUITING Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

NCT07040592

RECRUITING

Off Treatment Urinary Copper Excretion in Wilson Disease, Pilot Study

NCT07301216

RECRUITING NA

Non-invasive Venous Pressure Estimation

NCT07226479

RECRUITING NA

Project Women's Insomnia Sleep Health Equity Study (WISHES)

NCT06348082

RECRUITING Phase 1

Saci Nivo Rela for TNBC

NCT06963905

RECRUITING Phase 2

Luspatercept + Darbepoetin in MDS

NCT07096297

RECRUITING Phase 2

FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

NCT06917313

RECRUITING NA

RCT of Cervical Ripening Double Ballon Catheter Prior to Dilation and Evacuation.

NCT07200115

RECRUITING

Identification of Brain Injury Using Portable MRI

NCT07197918

RECRUITING Phase 2

Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma

NCT07048457

RECRUITING NA

Shared Decision Making to Treat Or Prevent (STOP) HIV in Justice Populations (R33)

NCT07223398

RECRUITING NA

New Mechanisms of Obesity

NCT06768827

RECRUITING NA

Neural Mechanisms of the Social Brain

NCT07457567

RECRUITING NA

Parent-Based Treatment for Adolescent Anxiety

NCT07219992

RECRUITING NA

Hyperfractionated Dual Equivalent Fractionated Radiation Therapy

NCT06898905

RECRUITING NA

SORE Study: Sitz Baths After Urogynecologic Reconstruction

NCT07215780

RECRUITING NA

Lifestyle, Exercise, And Nutrition (LEAN) Trial on Pathologic Complete Response in TNBC

NCT07066189

RECRUITING

Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images

NCT07228429

RECRUITING Phase 2

A Trial of Varenicline for E-cigarette Cessation

NCT07040566

RECRUITING NA

Subcortical Arousal in Perceptual Awareness

NCT06934356

RECRUITING NA

A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure

NCT06671015

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Yale University pipeline card: 1,492 registered trials from official public datasets.Report a data error.