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NCT06740487 · ClinicalTrials.gov registry record · NA

Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder

A NA study of Post Traumatic Stress Disorder and PTSD, sponsored by Wayne State University.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT06740487: Recruiting NA study of Post Traumatic Stress Disorder and PTSD, sponsored by Wayne State University.

NCT06740487 is a NA study of Post Traumatic Stress Disorder and PTSD that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 40 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06740487, a NA study of Post Traumatic Stress Disorder and PTSD, is actively recruiting participants, sponsored by Wayne State University.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The goal of this trial is to test how augmented reality exposure therapy (ARET) may potentiate the effects of traditional exposure therapy administered to U.S. military personnel diagnosed with PTSD. 40 adult males and females over the age of 18 that have served, or are currently serving, in the U.S. military, with a current diagnosis of PTSD, will be recruited. Participants will be randomized into two groups: 20 participants will receive ARET + traditional ET, with the remaining 20 to receive traditional ET only. The main questions this trial aims to answer are: * what are the different clinical and psychosocial functioning outcomes between veterans/active-duty personnel with PTSD who receive ARET + traditional ET versus traditional ET only * what are the differences in acceptance and satisfaction of treatment, between ARET + traditional ET and the traditional ET-only group

Primary Outcome

The CAPS-5 R is a 30-item structured interview conducted by a clinician with a patient, to assess for presence of PTSD and/or severity of PTSD symptoms, according to the DSM-5 criteria (prior text generated with help of AI). For each item, the clinician asks the patient the frequency with which they've had a specific problem in the past month, in addition to more specific questions depending on the problem being explored.

Conditions Studied

Post Traumatic Stress Disorder PTSD

Interventions

  • BEHAVIORAL Traditional Exposure Therapy (ET) Treatment
  • BEHAVIORAL Stepwise Augmented Reality (AR) Component with Traditional Exposure Treatment for Nonresponders

Study Locations (1)

South Carolina

  • Ralph H. Johnson VA Health Care System - Charleston

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-09-01
Est. Completion 2027-12-31
Phase NA
Wayne State University

163 total trials

What NCT06740487 shows while recruiting

NCT06740487 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (94% lower).

The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Traditional Exposure Therapy (ET) Treatment is the first listed.

NCT06740487 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT06740487 about?

NCT06740487 is a clinical study titled "Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder". The goal of this trial is to test how augmented reality exposure therapy (ARET) may potentiate the effects of traditional exposure therapy administered to U.S. military personnel diagnosed with PTSD. 40 adult males and females over the age of 18 that have served, or are currently serving, in the U.S...

What is the current status of trial NCT06740487?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-09-01. Estimated completion is 2027-12-31.

What conditions does trial NCT06740487 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, PTSD.

What interventions are being tested in trial NCT06740487?

The interventions under investigation include: Traditional Exposure Therapy (ET) Treatment (BEHAVIORAL), Stepwise Augmented Reality (AR) Component with Traditional Exposure Treatment for Nonresponders (BEHAVIORAL).

Who is sponsoring clinical trial NCT06740487?

This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06740487 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06740487's enrollment target sits among peer trials

40 187th of 262 higher than 65 of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06740487

Source: ClinicalTrials.gov NCT06740487, the US trial registry maintained by the National Library of Medicine. NCT06740487 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.