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Post Traumatic Stress Disorder: early-phase trial registry
110 of 265 indexed Post Traumatic Stress Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #37 of 28,707 conditions by registered trial count.
265 US clinical trials · 110 currently recruiting · #37 of 28,707 conditions by registered trial count
Post Traumatic Stress Disorder: 265 US clinical trials tracked, 110 recruiting.
Post Traumatic Stress Disorder is the subject of 265 registered US clinical trials on ClinicalTrials.gov, 110 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 45 of these trials.
Enrollment posture brief
Registry condition post-traumatic-stress-disorder
OPEN 110 | RECR 42% | LATE 22 | EARLY 46 | RANK #37 | SPON 45
Volume-matched condition peers
Nearest open-share peer: Glaucoma (41% recruiting · 94 trials)
Post Traumatic Stress Disorder lists 110 open slots (42% of 265 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Post Traumatic Stress Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Post Traumatic Stress Disorder is recruiting above its size-band peers.
110 of 265 indexed trials (41.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Post Traumatic Stress Disorder research.
VA Office of Research and Development accounts for 45 of 265 trials (17%). 130 distinct sponsors appear on at least one study for this condition label.
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Typical Post Traumatic Stress Disorder enrolment sits around 81 participants.
Median target enrolment is 81 among the 263 trials that report a genuine target (sentinel values excluded). 149 of those (56.7%) plan for fewer than 100 participants.
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Post Traumatic Stress Disorder research is mostly interventional.
250 interventional and 15 observational studies make up this index (94.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
265 total, page 3 of 6
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
Massachusetts General Hospital
NCT06429293
Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD
Montefiore Medical Center
NCT05929911
Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD
VA Office of Research and Development
NCT05478759
eTMS for Veterans and First Responders With PTSD
Virginia Polytechnic Institute and State University
NCT06294106
Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder
University of Tul
NCT02242110
MDMA-assisted Massed Prolonged Exposure for PTSD
Healing Breakthrough
NCT06117306
An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
Donald Jeffrey Newport
NCT05254405
Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers
Weill Medical College of Cornell University
NCT04887116
MDMA for AUD/PTSD Comorbidity
Carolina L Haass-Koffler
NCT05943665
Responsive Neurostimulation for Post-Traumatic Stress Disorder
VA Greater Los Angeles Healthcare System
NCT04152993
Stress, Adjustment And Growth In Children With Cancer And Their Parents
St. Jude Children's Research Hospital
NCT01044160
Stellate Ganglion Block for PTSD
VA Office of Research and Development
NCT05169190
Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD
Stanford University
NCT05037175
CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)
University of Washington
NCT06648395
A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD
University of Pennsylvania
NCT04961190
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Efficacy of Virtual Warrior Renew Therapy for Veterans Who Experienced Military Sexual Trauma
Seattle Institute for Biomedical and Clinical Research
NCT05776719
A Case Formulation Approach to Cognitive Processing Therapy
VA Office of Research and Development
NCT04407767
Multisite Feasibility of Compassion Meditation for Veterans With Posttraumatic Stress Disorder (PTSD)
Veterans Medical Research Foundation
NCT04793698
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
VA Office of Research and Development
NCT03539614
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
University of Washington
NCT04124380
Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Therapy
VA Office of Research and Development
NCT05797441
Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations
NYU Langone Health
NCT06307340
Web-administered STAIR for Patients on Behavioral Health Waitlists
Boston Medical Center
NCT06431022
MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence
Michigan State University
NCT05106361
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
Wayne State University
NCT05474534
Using Data Science To Center Patient Perspectives in Mechanism Discovery
Cambridge Health Alliance
NCT06233968
TMS for PTSD and Blood Pressure
Lifespan
NCT05512143
A Study of Psilocybin for PTSD
Johns Hopkins University
NCT06407635
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
Wayne State University
NCT06054412
tAN for PTSD and OUD in Buprenorphine Therapy
University of Cincinnati
NCT06130501
Targeted Plasticity Therapy for Posttraumatic Stress Disorder
Baylor Research Institute
NCT04064762
Rare Group Problem Management Plus
Children's National Research Institute
NCT06548022
LED Treatment to Improve Cognition and Promote Recovery in TBI
VA Office of Research and Development
NCT02404402
Pilot rTMS for AUD+mTBI
VA Office of Research and Development
NCT03995173
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
VA Office of Research and Development
NCT00958061
National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database
Hugo W. Moser Research Institute at Kennedy Krieger
NCT01591694
Evaluating the Effects of Stress in Pregnancy
Emory University
NCT00525226
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
University of New Hampshire
NCT03488927
Remotely Resolving Psychological Stress (Remote RePS)
University of California, San Francisco
NCT03196999
Acute Intervention to Reduce Distress Following Sexual Assault
Medical University of South Carolina
NCT01622855
The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women
Dartmouth-Hitchcock Medical Center
NCT00183716
Comparing Group Therapies for Veterans With Depression and PTSD
VA Office of Research and Development
NCT03979040
Effectiveness of Peer-Delivered Trauma-Specific Treatment
University of New Mexi
NCT02081417
Cognitive-Behavioral Conjoint Therapy (CBCT) Project
VA Office of Research and Development
NCT02720016
ALTO-100 in MDD and/or PTSD
Alto Neuroscience
NCT05117632
Neural Markers and Rehabilitation of Executive Functioning in Veterans With Traumatic Brain Injury and Posttraumatic Stress Disorder
University of North Carolina, Chapel Hill
NCT01410721
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
VA Eastern Colorado Health Care System
NCT01502436
A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD)
Bionomics Limited
NCT04951076
The Family of Heroes: an Evaluation of an Online Educational Tool
Department of Veterans Affairs, New Jersey
NCT01554839
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 31 |
| Phase 3 | 11 |
| Phase 4 | 11 |
Top Sponsors
Named interventions
Most-linked intervention names on Post Traumatic Stress Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Post Traumatic Stress Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Post Traumatic Stress Disorder page
265 registered trials, 110 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 110 Post Traumatic Stress Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Post Traumatic Stress Disorder trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post Traumatic Stress Disorder condition card totals 265 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.