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Post Traumatic Stress Disorder clinical trials
71 of 146 indexed Post Traumatic Stress Disorder trials are currently recruiting.
146 US clinical trials · 71 currently recruiting
Post Traumatic Stress Disorder is the subject of 146 registered US clinical trials on ClinicalTrials.gov, 71 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 30 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 19 of these trials.
The research picture
Post Traumatic Stress Disorder has 146 registered US clinical trials, 71 of them open to new participants right now, about 49% of the total.
- 71
- recruiting participants now
- 49%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 19
- top sponsor: VA Office of Research and Development
Active & Recent Trials
146 total, page 3 of 3
Effects of Early Abuse on Adult Intimate Relationships
University of Texas at Austin
NCT01803802
Treatment of Smoking Among Individuals With PTSD
University of Pennsylvania
NCT00937235
Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
Office of Naval Research (ONR)
NCT00992953
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Indiana University
NCT02213900
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
US Department of Veterans Affairs
NCT00108628
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
University of Washington
NCT00619255
PTSD Affect Labeling Study
University of California, Los Angeles
NCT05924399
Cannabidiol as a Treatment for AUD Comorbid With PTSD
NYU Langone Health
NCT03248167
Psychological Symptoms and Families of COVID-19 Patients
Rush University Medical Center
NCT04501445
Comparison of Videoconference and Face-to-Face Delivery of Cognitive Processing Therapy for Posttraumatic Stress Disorder
University of Wisconsin, Madison
NCT00941629
Mobile Self-Tracking of Mental Health
VA Office of Research and Development
NCT05023252
Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
US Department of Veterans Affairs
NCT00539279
Effectiveness of Cognitive, Exposure, and Skills Group Manualized Treatments in Operations Iraqi (OIF)/Operation Enduring Freedom (OEF) Female Veterans
New Mexico VA Healthcare System
NCT02069873
Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury
VA Office of Research and Development
NCT00676182
Primary-Care Based Mindfulness Intervention
Emory University
NCT03922581
Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
VA Office of Research and Development
NCT01921179
Biological Signatures, Probiotic Among Those With mTBI and PTSD
VA Office of Research and Development
NCT02723344
Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings
The University of Texas Health Science Center at San Antonio
NCT02290639
Physiological Augmentation of Mindfulness Meditation
Emory University
NCT02754557
Increasing Engagement in Evidence-Based PTSD Therapy for Primary Care Veterans
VA Office of Research and Development
NCT01984515
Bringing What Works to Youth in Corrections: A Trauma Intervention
University of Texas at Austin
NCT01560728
Primary Care Brief Mindfulness Training for Veterans With PTSD
Syracuse VA Medical Center
NCT03352011
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
Georgetown University
NCT03206437
The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety
Indiana University
NCT04999852
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
Massachusetts General Hospital
NCT00158262
Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial
University of Georgia
NCT05097352
Role of Substance P in Post-Traumatic Stress Disorder
National Institute of Mental Health (NIMH)
NCT00102102
Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD
VA Office of Research and Development
NCT03681288
Yoga and Mantram for Chronic Pain and PTSD
VA Office of Research and Development
NCT03816007
Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD
Albany Research Institute
NCT05895318
Frontline Clinician Psilocybin Study
University of Washington
NCT05163496
Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors
University of North Carolina, Chapel Hill
NCT06571513
Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio
NCT04280965
Maximizing Treatment Outcome in Post-Traumatic Stress Disorder (PTSD)
University of Texas at Austin
NCT01998100
Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
VA Office of Research and Development
NCT01031979
Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy
The University of Texas Health Science Center at San Antonio
NCT05419999
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
Summa Health System
NCT00554320
Body-Oriented Therapy for Sexual Abuse Recovery
National Center for Complementary and Integrative Health (NCCIH)
NCT00097305
The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.
Northport Veterans Affairs Medical Center
NCT01512771
Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
University of Massachusetts, Worcester
NCT03845985
Trauma Intervention for Affect Regulation, AIDS, and Substances
University of Miami
NCT02923141
Short Course Glucocorticoid Treatment for PTSD
University of Wisconsin, Madison
NCT00204737
CCTAP: Cognitive Control Training for Treatment of AUD-PTSD
Posit Science Corporation
NCT03200028
Maximizing Treatment Outcome and Examining Sleep in Post-traumatic Stress Disorder (PTSD)
Southern Methodist University
NCT01199107
Pilot Study of PRX-03140 to Assess Safety for Use in Adult Subjects With Post Traumatic Stress Disorder
Alachua Government Services
NCT01492699
Hyporeactivity and Gulf War Illness
US Department of Veterans Affairs
NCT00100412
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 22 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Post Traumatic Stress Disorder Trial Landscape
146 indexed Post Traumatic Stress Disorder studies · 71 recruiting (49%).
Phase mix: 13 late (III/IV) vs 30 early (I/II).
Top sponsor: VA Office of Research and Development (19 trials), 9 others listed. 46 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Post Traumatic Stress Disorder?
PlainTrial tracks 146 US clinical trials for Post Traumatic Stress Disorder, of which 71 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Post Traumatic Stress Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.