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NCT06629064 · ClinicalTrials.gov registry record · NA
Cognitive Control Training for Extinction in PTSD
A NA study of Post Traumatic Stress Disorder and PTSD, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06629064: Recruiting NA study of Post Traumatic Stress Disorder and PTSD, sponsored by VA Office of Research and Development.
NCT06629064 is a NA study of Post Traumatic Stress Disorder and PTSD that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 120 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06629064, a NA study of Post Traumatic Stress Disorder and PTSD, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed study will test whether a working memory training (WMT) program improves fear extinction learning and its underlying neural circuitry in Veterans with posttraumatic stress disorder (PTSD). WMT is designed to improves the ability to maintain task-relevant information in mind. The project will further validate the relationship between working memory and fear extinction using novel computational and multivariate analyses that link to specific PTSD symptoms. If WMT can enhance fear extinction learning, then WMT may be a powerful adjunctive treatment that can enhance exposure therapy outcomes or be leveraged as a stand-alone treatment. This project supports the Department of Veteran Affairs mission of developing viable targets of treatment for Veterans with PTSD.
Primary Outcome
Threat Expectancy Ratings. Behavioral ratings will be collected during the extinction learning task. Responses will be on scale of 1- 4. High scores reflect greater threat expectancy. It is expected that the working memory training group (WMT) will have lower threat expectancy ratings during extinction learning than the Sham group.
Conditions Studied
Interventions
- BEHAVIORAL Working Memory Training
- OTHER Sham Training
Study Locations (1)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2024-10-01 |
| Est. Completion | 2028-09-30 |
| Phase | NA |
What NCT06629064 shows while recruiting
NCT06629064 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower).
The record links to 5 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Working Memory Training is the first listed.
NCT06629064 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06629064 about?
NCT06629064 is a clinical study titled "Cognitive Control Training for Extinction in PTSD". The proposed study will test whether a working memory training (WMT) program improves fear extinction learning and its underlying neural circuitry in Veterans with posttraumatic stress disorder (PTSD). WMT is designed to improves the ability to maintain task-relevant information in mind. The project...
What is the current status of trial NCT06629064?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2024-10-01. Estimated completion is 2028-09-30.
What conditions does trial NCT06629064 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, PTSD, Trauma and Stressor Related Disorders, Post-Traumatic Stress Disorders, Stress Disorders, Traumatic.
What interventions are being tested in trial NCT06629064?
The interventions under investigation include: Working Memory Training (BEHAVIORAL), Sham Training (OTHER).
Who is sponsoring clinical trial NCT06629064?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06629064 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06629064's enrollment target sits among peer trials
120 96th of 262 higher than 158 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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