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NCT06218381 · ClinicalTrials.gov registry record · NA
The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans
A NA study of Post Traumatic Stress Disorder, sponsored by Children's Hospital Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06218381: Recruiting NA study of Post Traumatic Stress Disorder, sponsored by Children's Hospital Los Angeles.
NCT06218381 is a NA study of Post Traumatic Stress Disorder that is actively recruiting participants, run by Children's Hospital Los Angeles. The registered enrollment target is 80 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06218381, a NA study of Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Children's Hospital Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli. The main questions it aims to answer are: 1. How does Very Brief Exposure (combat images and control everyday images) and Visible Exposure to combat stimuli affect brain activity and subjective fear ratings? 2. To what extent are participants aware of the stimuli presented and tolerating the exposures? All participants will view both very brief exposure and visible exposure to combat stimuli in the functional magnetic brain imaging (fMRI) scan. They will provide ratings of fear, awareness, and tolerability. Researchers will compare U.S. combat veterans with PTSD and healthy controls to confirm differences in brain region activation and ratings.
Primary Outcome
A hypothesis-driven, group-level analysis will test brain activity, measured as Blood Oxygen Level Dependent (BOLD) response, in 4 regions of interest while minimizing Type II error.
Conditions Studied
Interventions
- OTHER Very Brief Exposure to Combat Images
Study Locations (1)
California
- Brain Imaging Lab - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-03-22 |
| Est. Completion | 2027-07 |
| Phase | NA |
What NCT06218381 shows while recruiting
NCT06218381 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Very Brief Exposure to Combat Images is the first listed.
NCT06218381 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06218381 about?
NCT06218381 is a clinical study titled "The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans". The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli. The main questions it aims to answer are: 1. How does Very Brief Exposure (combat images and control everyday ...
What is the current status of trial NCT06218381?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-03-22. Estimated completion is 2027-07.
What conditions does trial NCT06218381 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT06218381?
The interventions under investigation include: Very Brief Exposure to Combat Images (OTHER).
Who is sponsoring clinical trial NCT06218381?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06218381 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06218381's enrollment target sits among peer trials
80 135th of 262 higher than 121 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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