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NCT03906253 · ClinicalTrials.gov registry record · NA

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

A NA study of Aging and Actinic Keratoses, sponsored by Wright State University.

Recruiting
Registry status
NA
Development phase
72
Enrollment target
1
Study location

NCT03906253: Recruiting NA study of Aging and Actinic Keratoses, sponsored by Wright State University.

NCT03906253 is a NA study of Aging and Actinic Keratoses that is actively recruiting participants, run by Wright State University. The registered enrollment target is 72 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03906253, a NA study of Aging and Actinic Keratoses, is actively recruiting participants, sponsored by Wright State University.

RECRUITING
Registry status
NA
Development phase
72 participants
Enrollment target
1
Study location

Study Summary

This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects. The treatment of geriatric skin with dermal rejuvenation therapies (dermabrasion, fractionated laser resurfacing) restores the appropriate UVB response. Ongoing studies have tested the ability of fractionated laser resurfacing (FLR) to assess how long this wounding effect lasts-and have found that this appears to be a durable response which lasts for at least two years. The findings that FLR protects geriatric skin at two years is the impetus for this study. This study is an interventional study to assess if FLR treatment of one forearm of geriatric subjects with multiple actinic keratosis will result in the short-term removal of actinic keratosis, and the long-term decrease in levels of future actinic keratosis and other non-melanoma skin cancers in comparison to the untreated arm. Study length and visit: The first part of the study is completed in 1 day then there are follow up visits at 90 days and every 6 months for 5 years.

Primary Outcome

Investigator will assess the number of actinic keratosis on both forearms.

Interventions

  • DEVICE Fractionated Laser Resurfacing

Study Locations (1)

Ohio

  • Dayton VA Medical Center - Dayton

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2018-01-10
Est. Completion 2028-12
Phase NA
Wright State University

32 total trials

What NCT03906253 shows while recruiting

NCT03906253 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower).

The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Fractionated Laser Resurfacing is the first listed.

NCT03906253 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT03906253 about?

NCT03906253 is a clinical study titled "Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia". This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects. The treatment of geriatric skin with dermal rejuvenation therapies (dermabrasion, fractionated laser resurfacing) restores the appropriate...

What is the current status of trial NCT03906253?

This trial is currently recruiting. It is a NA study. The enrollment target is 72 participants. The study started on 2018-01-10. Estimated completion is 2028-12.

What conditions does trial NCT03906253 study?

This clinical trial studies the following conditions: Aging, Actinic Keratoses, Non-Melanoma Skin Cancer.

What interventions are being tested in trial NCT03906253?

The interventions under investigation include: Fractionated Laser Resurfacing (DEVICE).

Who is sponsoring clinical trial NCT03906253?

This trial is sponsored by Wright State University, which has 32 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03906253 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aging

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03906253's enrollment target sits among peer trials

72 118th of 262 higher than 140 of 262 other Aging trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03906253, the US trial registry maintained by the National Library of Medicine. NCT03906253 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.