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NCT05457725 · ClinicalTrials.gov registry record · NA
Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
A NA study of Aging and Cognitive Change, sponsored by University of Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 68
- Enrollment target
- 1
- Study location
NCT05457725 is a NA study of Aging and Cognitive Change that is actively recruiting participants, run by University of Florida. The registered enrollment target is 68 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05457725, a NA study of Aging and Cognitive Change, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
- 1
- Study location
Study Summary
Much of human interaction is based on trust. Aging has been associated with deficits in trust-related decision making, likely further exacerbated in age-associated neurodegenerative disease (Alzheimer's disease/AD), possibly underlying the dramatically growing public health problem of elder fraud. Optimal trust-related decision making and avoiding exploitation require the ability to learn about the trustworthiness of social partners across multiple interactions, but the role that learning plays in determining age deficits in trust decisions is currently unknown. Aim: Probe the malleability of the underlying neurocircuitry of trust-learning deficits in aging. This study will utilize real-time fMRI neurofeedback to train older adults in brain activity up-regulation toward enhanced trust-related learning in aging and confirm critical mechanisms of experience-dependent social decisions in aging. Grant R01AG072658 Aim 3: Test the malleability of trust-learning neurocircuitry toward optimized trust-related decision making in aging.
Conditions Studied
Interventions
- BEHAVIORAL Contingent rtfMRI neurofeedback training
- BEHAVIORAL Non-contingent/sham rtfMRI neurofeedback training
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2024-10-08 |
| Est. Completion | 2027-04-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05457725
The ClinicalTrials.gov registry entry for NCT05457725 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 68 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Contingent rtfMRI neurofeedback training is the first listed.
NCT05457725 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT05457725 about?
NCT05457725 is a clinical study titled "Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging". Much of human interaction is based on trust. Aging has been associated with deficits in trust-related decision making, likely further exacerbated in age-associated neurodegenerative disease (Alzheimer's disease/AD), possibly underlying the dramatically growing public health problem of elder fraud. O...
What is the current status of trial NCT05457725?
This trial is currently recruiting. It is a NA study. The enrollment target is 68 participants. The study started on 2024-10-08. Estimated completion is 2027-04-30.
What conditions does trial NCT05457725 study?
This clinical trial studies the following conditions: Aging, Cognitive Change, Neurocognitive Disorders, Mild.
What interventions are being tested in trial NCT05457725?
The interventions under investigation include: Contingent rtfMRI neurofeedback training (BEHAVIORAL), Non-contingent/sham rtfMRI neurofeedback training (BEHAVIORAL).
Who is sponsoring clinical trial NCT05457725?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05457725 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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