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RECRUITING Early Phase 1

Transient Receptor Potential Channels

NCT06444594 · View on ClinicalTrials.gov ↗

Study Summary

Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili peppers, garlic, etc. The aim of the study is to examine how topically applied TRP channel agonists including menthol, capsaicin and camphor impact neurovascular responses in the skin.

Conditions Studied

Interventions

  • DRUG TRPM8 Agonist
  • DRUG TRPV1 Agonist
  • DRUG TRPV4 Agonist
  • DRUG TRPM8, TRPV4, TRPV1 Agonists
  • OTHER Vehicle gel

Study Locations (1)

Pennsylvania

  • Noll Laboratory — University Park

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2024-07-17
Est. Completion 2026-12-31
Phase Early Phase 1

Sponsor

Penn State University

233 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06444594

The ClinicalTrials.gov registry entry for NCT06444594 describes a study currently listed as recruiting. It is categorized as Early Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Penn State University, which has 233 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 5 interventions — of which TRPM8 Agonist is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06444594 reports 1 study location spanning 1 distinct geographic area — top geographies include Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06444594 about?

NCT06444594 is a clinical study titled "Transient Receptor Potential Channels". Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili peppers, garlic, etc. The aim of the study is to examine how topically a...

What is the current status of trial NCT06444594?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 45 participants. The study started on 2024-07-17. Estimated completion is 2026-12-31.

What conditions does trial NCT06444594 study?

This clinical trial studies the following conditions: Aging. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06444594?

The interventions under investigation include: TRPM8 Agonist (DRUG), TRPV1 Agonist (DRUG), TRPV4 Agonist (DRUG), TRPM8, TRPV4, TRPV1 Agonists (DRUG), Vehicle gel (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06444594?

This trial is sponsored by Penn State University, which has 233 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06444594 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial