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NCT04971954 · ClinicalTrials.gov registry record · NA
Using Nicotine to Reverse Age-related Auditory Processing Deficits
A NA study of Aging and Auditory Perceptual Impairment, sponsored by University of California, Irvine.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT04971954: Recruiting NA study of Aging and Auditory Perceptual Impairment, sponsored by University of California, Irvine.
NCT04971954 is a NA study of Aging and Auditory Perceptual Impairment that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 48 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04971954, a NA study of Aging and Auditory Perceptual Impairment, is actively recruiting participants, sponsored by University of California, Irvine.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participants in the form of gum that is available as an over-the-counter medication. The hypothesis is that nicotine will reverse the detrimental effects of aging on auditory processing. The proposed experiments will characterize the effects of nicotine and may eventually lead to improved treatments of hearing loss in a variety of patient populations and in healthy aging.
Primary Outcome
Hearing thresholds in dB SPL will be measured as a function of sound frequency from 125 Hz to 8000 Hz in quiet or in noise.
Conditions Studied
Interventions
- OTHER Nicotine gum
- OTHER Placebo gum
Study Locations (1)
California
- Hearing and Speech Lab - Irvine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT04971954 shows while recruiting
NCT04971954 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Nicotine gum is the first listed.
NCT04971954 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04971954 about?
NCT04971954 is a clinical study titled "Using Nicotine to Reverse Age-related Auditory Processing Deficits". The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participants in the form of gum that is available as an over-the-counter medication. The hypothesis is that nicotine will reverse t...
What is the current status of trial NCT04971954?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2022-02-01. Estimated completion is 2026-06-30.
What conditions does trial NCT04971954 study?
This clinical trial studies the following conditions: Aging, Auditory Perceptual Impairment.
What interventions are being tested in trial NCT04971954?
The interventions under investigation include: Nicotine gum (OTHER), Placebo gum (OTHER).
Who is sponsoring clinical trial NCT04971954?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04971954 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04971954's enrollment target sits among peer trials
48 159th of 262 higher than 103 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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