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NCT07171450 · ClinicalTrials.gov registry record · NA
Cognitive Remediation
A NA study of Aging and Inflammation, sponsored by Cutter Lindbergh.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT07171450: Recruiting NA study of Aging and Inflammation, sponsored by Cutter Lindbergh.
NCT07171450 is a NA study of Aging and Inflammation that is actively recruiting participants, run by Cutter Lindbergh. The registered enrollment target is 75 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07171450, a NA study of Aging and Inflammation, is actively recruiting participants, sponsored by Cutter Lindbergh.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Primary Outcome
Part B of the Trail Making Test (Trails B) is an executive functioning measure of set-shifting abilities in which the examinee must rapidly alternate between connecting numbers and letters distributed across a page. The total time (in seconds) required for the examinee to complete the task is recorded. Lower scores (in seconds) indicate better performance. Time to complete Trails B at the post-treatment visit will be compared between treatment groups (i.e., NeuroFlex vs. Active Control Condition
Conditions Studied
Interventions
- OTHER Computerized Cognitive Remediation
- OTHER Alternative Computer Activities
Study Locations (1)
Connecticut
- UConn Health - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2026-01-21 |
| Est. Completion | 2030-02-28 |
| Phase | NA |
What NCT07171450 shows while recruiting
NCT07171450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower).
The record links to 6 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Computerized Cognitive Remediation is the first listed.
NCT07171450 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT07171450 about?
NCT07171450 is a clinical study titled "Cognitive Remediation". The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims...
What is the current status of trial NCT07171450?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2026-01-21. Estimated completion is 2030-02-28.
What conditions does trial NCT07171450 study?
This clinical trial studies the following conditions: Aging, Inflammation, Cognitive Dysfunction, Cognitive Remediation, Postviral Syndrome.
What interventions are being tested in trial NCT07171450?
The interventions under investigation include: Computerized Cognitive Remediation (OTHER), Alternative Computer Activities (OTHER).
Who is sponsoring clinical trial NCT07171450?
This trial is sponsored by Cutter Lindbergh, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07171450 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07171450's enrollment target sits among peer trials
75 115th of 262 higher than 146 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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