Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Aging: early-phase trial registry
126 of 263 indexed Aging trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #38 of 28,707 conditions by registered trial count.
263 US clinical trials · 126 currently recruiting · #38 of 28,707 conditions by registered trial count
Aging: 263 US clinical trials tracked, 126 recruiting.
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
Enrollment posture brief
Registry condition aging
OPEN 126 | RECR 48% | LATE 14 | EARLY 48 | RANK #38 | SPON 14
Volume-matched condition peers
Nearest open-share peer: Lung Non-Small Cell Carcinoma (48% recruiting · 48 trials)
Aging lists 126 open slots (48% of 263 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Aging on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Aging is recruiting above its size-band peers.
126 of 263 indexed trials (47.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Aging trials is spread across many organizations.
University of Florida accounts for 14 of 263 trials (5.3%). 132 distinct sponsors appear on at least one study for this condition label.
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Most Aging trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 263 trials that report a genuine target (sentinel values excluded). 166 of those (63.1%) plan for fewer than 100 participants.
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Aging research is mostly interventional.
228 interventional and 35 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
263 total, page 1 of 6
Apple Health Study
Apple
NCT06958523
The Lake Nona Life Project
University of Central Florida
NCT02533804
Baltimore Longitudinal Study of Aging
National Institute on Aging (NIA)
NCT00233272
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2
Massachusetts General Hospital
NCT07166861
Enhancing Attention and Wellbeing Using Digital Therapeutics
University of California, San Francisco
NCT06397469
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
University of Colorado, Denver
NCT06953375
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
University of Michigan
NCT05929703
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
Neurobehavioral Systems
NCT04800588
Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
University of North Carolina, Chapel Hill
NCT06239688
DC Longitudinal Study on Aging and Specimen Bank
Georgetown University
NCT03702907
Vanderbilt Memory and Aging Project
Vanderbilt University Medical Center
NCT05372159
Tennessee Alzheimer's Project
Vanderbilt University Medical Center
NCT05372172
Arlington Aging Study
The University of Texas at Arlington
NCT06857877
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Marquette University
NCT05344001
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
National Institute on Aging (NIA)
NCT07099053
A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment
Oregon Research Institute
NCT05725668
The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults
Mayo Clinic
NCT06940037
Exercise to Improve Brain Health in Older African Americans
Rutgers, The State University of New Jersey
NCT05597124
MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression
VA Office of Research and Development
NCT05220202
Clean Hands Accessible and Manageable for Patients (CHAMPs)
Case Western Reserve University
NCT05866393
Molecular Indicators of Systematic Fitness
VO Health
NCT07393841
Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men
University of Colorado, Denver
NCT06912984
Arterial Stiffness and Blood Pressure
VA Office of Research and Development
NCT06495710
Synbiotic to Attenuate Resorption of the Skeleton
Hebrew SeniorLife
NCT06389539
The Effect of NAD Supplementation on Brain Vascular Health in Aging
University of Oklahoma
NCT05483465
SMART Exercise for PAD
Northwestern University
NCT06032065
The Role of the Locus Coeruleus in Age-related Distractibility
Virginia Polytechnic Institute and State University
NCT05574634
Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV
Butler Hospital
NCT05752500
RESTOR: PK/PD mTORi Inhibition in Older Adults
The University of Texas Health Science Center at San Antonio
NCT06658093
Identification of Critical Thermal Environments for Aged Adults
Penn State University
NCT04284397
Targeting Aging With a Ketone Ester for Function in Frailty
Buck Institute for Research on Aging
NCT06645847
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
University of Kansas Medical Center
NCT06123182
Brain Health Virtual Reality Study
University of California, San Diego
NCT06124339
Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults
University of Colorado, Boulder
NCT05300971
Gerofit and Cognition
VA Office of Research and Development
NCT06107842
BID WM Digital Intervention in Aging
University of California, San Francisco
NCT06918704
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
AgelessRx
NCT07092618
Understanding Aided Speech Perception in Noise
University of South Florida
NCT06377215
Technical Development of Multi-Parametric Renocerebral MRI
University of Minnesota
NCT02831335
Improving PCP Advance Care Planning for People With ADRD
University of Pittsburgh
NCT06565169
Mechanisms of Anabolic Resistance in Older Humans
Mayo Clinic
NCT06617195
Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait
Massachusetts Eye and Ear Infirmary
NCT06688578
Mode of Exercise and Bone Biomarkers in Older Veterans
VA Office of Research and Development
NCT05266976
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
Marquette University
NCT03888040
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Douglas Seals
NCT03821623
Influence of Brain Oscillation-Dependent TMS on Motor Function
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03288220
Inspiratory Muscle Strength Training in Chronic Kidney Disease
University of Colorado, Denver
NCT04911491
Tau PET in Imaging and Cognition: Healthy Adults From 55-90
Yaakov Stern
NCT03372317
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
University of Arizona
NCT06307574
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
Massachusetts General Hospital
NCT06554717
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Aging records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Aging trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Aging page
263 registered trials, 126 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 126 Aging trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Aging trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aging condition card totals 263 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.