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NCT06660979 · ClinicalTrials.gov registry record · NA
Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing
A NA study of Aging, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06660979 is a NA study of Aging that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 70 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06660979, a NA study of Aging, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall goal of the proposed research is to refine and adapt and perform efficacy testing of a novel reinforcement learning-based approach to personalizing EHR-based tools for PCPs on deprescribing of high-risk medications for older adults. The trial will be conducted at Atrius Health, an integrated delivery network in Massachusetts, and will intervene upon primary care providers. The investigators will conduct a cluster randomized trial using reinforcement learning to adapt electronic health record (EHR) tools for deprescribing high-risk medications versus usual care. 70 PCPs will be randomized (i.e., 35 each to the reinforcement learning intervention and usual care \[no EHR tool\] in each arm) to the trial and follow them for approximately 30 weeks. The primary outcome will be discontinuation or ordering a dose taper for the high-risk medications for eligible patients by included primary care providers, using EHR data at Atrius. The primary hypothesis is that the personalized intervention using reinforcement learning will improve deprescribing compared with usual care.
Conditions Studied
Interventions
- BEHAVIORAL Reinforcement learning
Study Locations (1)
Massachusetts
- Atrius Health - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-08-11 |
| Est. Completion | 2026-05-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06660979
The ClinicalTrials.gov registry entry for NCT06660979 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Reinforcement learning is the first listed.
NCT06660979 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06660979 about?
NCT06660979 is a clinical study titled "Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing". The overall goal of the proposed research is to refine and adapt and perform efficacy testing of a novel reinforcement learning-based approach to personalizing EHR-based tools for PCPs on deprescribing of high-risk medications for older adults. The trial will be conducted at Atrius Health, an integr...
What is the current status of trial NCT06660979?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2025-08-11. Estimated completion is 2026-05-31.
What conditions does trial NCT06660979 study?
This clinical trial studies the following conditions: Aging.
What interventions are being tested in trial NCT06660979?
The interventions under investigation include: Reinforcement learning (BEHAVIORAL).
Who is sponsoring clinical trial NCT06660979?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06660979 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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