VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 2 of 34

RECRUITING Phase 2

A New Intervention to Improve Function in Veterans With Anxiety and Depression

NCT06188923

RECRUITING NA

A Study to Improve Skeletal Muscle in Veterans With HIV

NCT06845046

RECRUITING NA

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT06619041

RECRUITING NA

Multilevel Intervention for Precision Oncology

NCT06825715

RECRUITING NA

VR Mindfulness Training for Veterans With SCI

NCT06587607

RECRUITING Phase 4

Computational Assessment of GABA Receptor Modulation in PTSD

NCT06852469

RECRUITING NA

Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

NCT06451874

RECRUITING NA

Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans

NCT06906185

RECRUITING NA

Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality

NCT05990062

RECRUITING Phase 2

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

NCT06745063

RECRUITING NA

Arterial Stiffness and Blood Pressure

NCT06495710

RECRUITING NA

Improving Sleep in Veterans With the Polytrauma Clinical Triad

NCT06477796

RECRUITING NA

COPEWeb Training for Providers

NCT05812131

RECRUITING NA

Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

NCT06607913

RECRUITING NA

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

NCT06454903

RECRUITING NA

Sensory Synchronized Imaging and Neuromodulation

NCT06548113

RECRUITING Phase 2

The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans

NCT06778434

RECRUITING NA

Pharmacogenomic Informed Statin Prescribing

NCT06568601

RECRUITING NA

Reliability and Validity of Continuous Inter-limb Stability

NCT06987019

RECRUITING NA

Dosing rTMS for Depression Post-SCI

NCT05553353

RECRUITING NA

Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)

NCT06378541

RECRUITING NA

Hearing Aids for Veterans With Functional Hearing Difficulties

NCT06117254

RECRUITING Phase 2

Suicide Risk Interventions

NCT05931289

RECRUITING NA

Enhancing Rehabilitation for Veterans With Serious Mental Illness

NCT06586164

RECRUITING

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

NCT06932237

RECRUITING NA

Pilot Study of Hospital GamePlan4Care

NCT06634368

RECRUITING NA

Fall Risk Identification and Management for Older Veterans

NCT06573983

RECRUITING Phase 2

Resistant Potato Starch to Alleviate GWI

NCT05820893

RECRUITING NA

Smoking Cessation CM for Veterans With or at Risk for Cancer

NCT06432985

RECRUITING NA

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

NCT06088355

RECRUITING Early Phase 1

Multisensory Augmentation for Post-stroke Standing Balance

NCT05760885

RECRUITING Phase 3

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

NCT04867317

RECRUITING NA

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

NCT06399653

RECRUITING NA

Care for Veterans Post-COVID-19

NCT05787379

RECRUITING Phase 2

Fiber and Calcium Absorption in Older Men

NCT06519877

RECRUITING NA

Water-based Activity to Enhance Recovery in Long COVID-19

NCT06142253

RECRUITING NA

Randomized Controlled Effectiveness Trial of VA S.A.V.E.

NCT06470867

RECRUITING NA

Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans

NCT06089746

RECRUITING NA

Mobile Anger Reduction Intervention

NCT06094933

RECRUITING NA

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

NCT06244199

RECRUITING NA

Auricular Neuromodulation in Veterans With Fibromyalgia

NCT06415591

RECRUITING NA

Combining a Smartphone App With Medications to Manage Heavy Drinking

NCT06303778

RECRUITING NA

Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia

NCT06574165

RECRUITING

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

NCT06405334

RECRUITING NA

Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

NCT06529094

RECRUITING Phase 2

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

NCT06194851

RECRUITING NA

Bright Light Therapy for OSA

NCT05917119

RECRUITING NA

Self-Injury Treatment and Recovery in Veterans

NCT05969080

RECRUITING NA

Enhancing Memory in CPT for PTSD

NCT06000475

RECRUITING NA

Increasing Veterans' Social Engagement and Connectedness

NCT06467214

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.