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RECRUITING NA

Arterial Stiffness and Blood Pressure

NCT06495710 · View on ClinicalTrials.gov ↗

Study Summary

Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension are less likely to be treated to goal blood pressure because there are conflicting recommendations for what constitutes "optimal" in older adults. The investigators have developed a novel way to non-invasively assess the components of blood vessel stiffness that is related to blood pressure (load-dependent stiffness). This project will generate new knowledge about how different blood pressure treatment goals (intensive vs standard) impact different components of arterial stiffness and if these differences can be explained through genetic analysis. Results from this project will offer the VA an updated blueprint for personalizing blood pressure care in older adults, ultimately improving cardiovascular health.

Interventions

  • OTHER Blood pressure treatment algorithm

Study Locations (3)

Alabama

  • Birmingham VA Medical Center, Birmingham, AL — Birmingham

Tennessee

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN — Nashville

Wisconsin

  • William S. Middleton Memorial Veterans Hospital, Madison, WI — Madison

Trial Details

FieldValue
Enrollment Target 228 participants
Start Date 2025-05-01
Est. Completion 2028-12-31
Phase NA

Sponsor

VA Office of Research and Development

1,863 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06495710

The ClinicalTrials.gov registry entry for NCT06495710 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 228 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,863 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention — of which Blood pressure treatment algorithm is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06495710 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Alabama, Tennessee, Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06495710 about?

NCT06495710 is a clinical study titled "Arterial Stiffness and Blood Pressure". Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension...

What is the current status of trial NCT06495710?

This trial is currently recruiting. It is a NA study. The enrollment target is 228 participants. The study started on 2025-05-01. Estimated completion is 2028-12-31.

What conditions does trial NCT06495710 study?

This clinical trial studies the following conditions: Hypertension, Aging, Vascular Stiffness. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06495710?

The interventions under investigation include: Blood pressure treatment algorithm (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06495710?

This trial is sponsored by VA Office of Research and Development, which has 1,863 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06495710 being conducted?

This trial has 3 study locations across Alabama, Tennessee, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial