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Stress Disorders, Post-Traumatic: early-phase trial registry
20 of 68 indexed Stress Disorders, Post-Traumatic trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #203 of 28,707 conditions by registered trial count.
68 US clinical trials · 20 currently recruiting · #203 of 28,707 conditions by registered trial count
Stress Disorders, Post-Traumatic: 68 US clinical trials tracked, 20 recruiting.
Stress Disorders, Post-Traumatic is the subject of 68 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 19 of these trials.
Enrollment posture brief
Registry condition stress-disorders-post-traumatic
OPEN 20 | RECR 29% | LATE 7 | EARLY 11 | RANK #203 | SPON 19
Volume-matched condition peers
Nearest open-share peer: Addiction (29% recruiting · 17 trials)
Stress Disorders, Post-Traumatic lists 20 open slots (29% of 68 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stress Disorders, Post-Traumatic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stress Disorders, Post-Traumatic is recruiting below its size-band peers.
20 of 68 indexed trials (29.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Stress Disorders, Post-Traumatic research.
VA Office of Research and Development accounts for 19 of 68 trials (27.9%). 42 distinct sponsors appear on at least one study for this condition label.
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Typical Stress Disorders, Post-Traumatic enrolment sits around 84 participants.
Median target enrolment is 84 among the 67 trials that report a genuine target (sentinel values excluded). 37 of those (55.2%) plan for fewer than 100 participants.
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Stress Disorders, Post-Traumatic research is mostly interventional.
61 interventional and 7 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
68 total, page 1 of 2
An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample
U.S. Army Medical Research and Development Command
NCT04180930
A Study of a Novel EEG Neurofeedback System for PTSD Treatment
Foundation for Atlanta Veterans Education and Research
NCT06770998
SMART Therapist Training: A Hybrid Factorial-SMART Design
VA Office of Research and Development
NCT07010770
Whole Health in VA Mental Health: Omnis Salutis
VA Office of Research and Development
NCT05400252
Manage Emotions to Reduce Aggression (MERA)
VA Office of Research and Development
NCT04793776
Massed Prolonged Exposure for PTSD in Substance Use Treatment
Veterans Medical Research Foundation
NCT06296186
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
VA Office of Research and Development
NCT03642028
Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
Veterans Medical Research Foundation
NCT06296589
Computational Assessment of GABA Receptor Modulation in PTSD
VA Office of Research and Development
NCT06852469
Combining Stellate Ganglion Block With Prolonged Exposure for PTSD
The University of Texas Health Science Center at San Antonio
NCT05889741
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
Portland State University
NCT06019377
Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder
VA Office of Research and Development
NCT05517304
Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery
Massachusetts General Hospital
NCT05853627
Overcontrol and Suicide in PTSD
VA Office of Research and Development
NCT06355284
Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial
Uniformed Services University of the Health Sciences
NCT05244564
Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication
Boston University
NCT06088303
Enhancing Memory in CPT for PTSD
VA Office of Research and Development
NCT06000475
Postpartum Care in the NICU (PeliCaN) Transitions
University of Pennsylvania
NCT06521398
MDMA for Co-occurring PTSD and OUD After Childbirth
University of New Mexi
NCT05219175
Healthy Recovery After Trauma Study
Christal L Badour
NCT04585685
Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study
VA Office of Research and Development
NCT00748995
Resettled Refugee Families for Healing
Washington University School of Medicine
NCT06176638
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
VA Office of Research and Development
NCT05220137
Multi-site, Longitudinal Trial Evaluating the Efficacy, Mechanisms, and Moderators of Service Dogs for Military Veterans With PTSD
University of Arizona
NCT05900479
Compassion Meditation vs. Health Education for Veterans
VA Office of Research and Development
NCT04651296
A Randomized Controlled Trial of Coaching Into Care With VA-CRAFT to Promote Veteran Engagement in PTSD Care
VA Office of Research and Development
NCT04501328
A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
San Francisco Veterans Affairs Medical Center
NCT03339258
Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder
Ohio State University
NCT05554094
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
US Department of Veterans Affairs
NCT00118534
Development and Validation of a PTSD-Related Functional Impairment Scale
Boston VA Research Institute
NCT00651872
Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment
Dartmouth-Hitchcock Medical Center
NCT01457391
Homecoming Line: Telephone Support for Veterans
VA Palo Alto Health Care System
NCT02655991
Comparing Effects of a Holistic Yoga Program and a Wellness Program on PTSD Symptoms
VA Office of Research and Development
NCT02234622
Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault
University of Pennsylvania
NCT00057629
Exposure Therapy for Active Duty Soldiers With Post Traumatic Stress Disorder
National Center for Telehealth and Technology
NCT01193725
Collaborative Care for Women Veterans
VA Office of Research and Development
NCT02950961
Project QueST 2023: Queer Survivors of Trauma
Syracuse University
NCT05569915
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
University of Washington
NCT05345405
CPT-SMART for Treatment of PTSD and Cigarette Smoking
VA Office of Research and Development
NCT03978442
Implementation of CPT for PTSD in Diverse Communities
Massachusetts General Hospital
NCT01702168
Evaluation of a Mobile Phone App for Veterans With PTSD
VA Palo Alto Health Care System
NCT03199742
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Yale University
NCT00744055
Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD
Medical University of South Carolina
NCT02755103
The Effects of Oxytocin on Startle Hyperreactivity in Patients With AUD and PTSD
University of California, San Francisco
NCT02469259
Improving Mind/Body Health and Functioning With Integrative Exercise
VA Office of Research and Development
NCT02856412
Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of Mifepristone
VA Office of Research and Development
NCT01739335
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
Dartmouth-Hitchcock Medical Center
NCT04637581
Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health
University of North Texas, Denton, TX
NCT05523453
The Effects of Home-Based Telemental Health for Rural Veterans With PTSD
VA Pacific Islands Health Care System
NCT02295410
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Billings Clinic
NCT05001399
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 8 |
| Phase 3 | 3 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Stress Disorders, Post-Traumatic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stress Disorders, Post-Traumatic trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stress Disorders, Post-Traumatic page
68 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 20 Stress Disorders, Post-Traumatic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stress Disorders, Post-Traumatic trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress Disorders, Post-Traumatic condition card totals 68 registered trials; most-linked intervention Prolonged Exposure Therapy; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.