Duke University
Trial Pipeline
Virtual Agent Feasibility in Oncology Patients (NTT Data)
NCT06682013
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
NCT07144228
Automated Applanation Tonometry - Updated
NCT07298356
Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors
NCT07471685
PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
NCT07101640
Using PrEP, Doing It for Ourselves
NCT06638892
Intestinal Microbiome Transplant in ALS
NCT07017946
Improving Hypertension Control in Rheumatoid Arthritis
NCT05760898
Development of a Pain Control Options Menu for IUD Insertion
NCT07278804
Allopregnanolone (Zuranolone) in Post-stroke Depression
NCT06759558
Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP
NCT07218211
Weight Management After Cancer for Survivors in Rural Communities
NCT07426952
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis
NCT06654882
Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment
NCT06532773
Yoga for Treatment of Overactive Bladder in Pediatric Patients
NCT05895045
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
NCT07220005
Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation
NCT07214350
Virtual Reality Use for ICU Mobility
NCT07234201
Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab
NCT06816927
Photon-counting CT in Chest Imaging
NCT07031336
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers
NCT07159269
HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT
NCT06731504
Pediatrics Mobile CT
NCT07166926
Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain
NCT06983678
Timing of Physician Rounds for Antepartum Patients
NCT07215507
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
NCT06906627
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
NCT06906640
Eat Well Heart Failure
NCT07101289
Safety of RSV Preventive Monoclonal Antibody
NCT07158814
Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging
NCT06177639
Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy
NCT06972719
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
NCT07089745
Repurposing Tilmanocept for Cardiac Sarcoidosis
NCT07159074
MAPS PrEP Van Study
NCT06908252
Improving Needs Among Older Adults
NCT06588556
Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)
NCT06428175
Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery
NCT07117708
HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM
NCT06822972
AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
NCT06619405
Pain With Dementia
NCT06854718
COMPASS Study for Metastatic Castration-resistant Prostate Cancer
NCT07050433
4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800
NCT07024719
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
NCT06909565
Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis
NCT06841562
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
NCT06371768
SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
NCT06627764
Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors
NCT06732375
Engage Psychosocial Intervention for Cancer Symptoms
NCT06555588
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
NCT06765642
DBT-P Treatment Study
NCT06963801
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
NCT06962306
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
NCT06971640
Assessing Better Bottles for Babies
NCT06357299
Urine Methylation Markers in UTUC
NCT06805630
Coping Skills Training for Symptom Management and Daily Steps (Step Up)
NCT06575712
Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery
NCT06986967
Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae
NCT06815536
Opioids, Low Nicotine Cigarettes, and Chronic Pain
NCT06747871
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction
NCT06733012
Role of Aging and Individual Variation in Exercise Training Responsiveness
NCT06471569
Ultrasound Simulation Case-based Workshop Implementation and Impact Assessment
NCT06960837
Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer
NCT06636721
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
NCT06041789
Collecting Outcomes and Managing Pain After Surgery
NCT03834818
Olfactory Biopsies
NCT07021040
OUD (Opioid Use Disorder) Target Trial
NCT06585709
Rare Glycogen Storage Diseases Natural History Study
NCT06795152
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
NCT06625684
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
NCT06576830
GERD in Children With Cystic Fibrosis
NCT06617013
Tolerability of an Anesthesia-free Tonometer Tip
NCT06585423
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
NCT06538246
PK/PD of Digoxin in Infants With SVHD
NCT06613477
Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
NCT06471036
Imaging Retinal Vasculature in Infant Eyes
NCT05558059
Cancer and Mild Cognitive Impairment Dyadic Intervention
NCT05144516
Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
NCT06399302
Bacterial Decolonization Within Dyads
NCT06541145
Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)
NCT05945355
Predictors of Pain in Sickle Cell Disease
NCT06139510
Intervention to Improve Communication and Medication Adherence in Lupus
NCT06458075
Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252
NCT06126744
Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health
NCT06116422
Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study
NCT06333925
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials
NCT06141993
IMPRoving Outcomes in Vascular DisEase - Aortic Dissection
NCT06087029
Personalized Nutrition to Improve Recovery in Trauma
NCT06065202
Neuromodulation of Memory in Aging
NCT05460468
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
NCT06069726
SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)
NCT06177977
Project humAn dieTary daTa rEtuRN
NCT06266689
Trans-Rectal Ultrasound of the Female Pelvis for Real-Time MRI-US Fusion Based Needle Tracking
NCT05977621
Optimize Pediatric OCT Imaging
NCT06139523
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
NCT05665465
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2
NCT06139458
Oxygen Toxicity: Mechanisms in Humans
NCT05761756
Mobile Neurofeedback for Low Back Pain
NCT05669027
Testing a Device for Automatically TRacking Urine and STool in an Inpatient HCT Setting (Project TRUST)
NCT05520346
The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions
NCT04140344
COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children
NCT06164028
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 94 |
| Phase 2 | 45 |
| Phase 3 | 9 |
| Phase 4 | 56 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,129 US clinical trials across every stage of research activity. Of those, 781 studies are currently recruiting — about 69% of the sponsor's indexed portfolio — and 296 are already marked complete, representing roughly 26% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Duke University reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 139 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.