Duke University

1,129 total trials 781 currently recruiting 296 completed

Trial Pipeline

RECRUITING NA

Virtual Agent Feasibility in Oncology Patients (NTT Data)

NCT06682013

RECRUITING

Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer

NCT07144228

RECRUITING NA

Automated Applanation Tonometry - Updated

NCT07298356

RECRUITING NA

Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors

NCT07471685

RECRUITING Phase 1

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

NCT07101640

RECRUITING NA

Using PrEP, Doing It for Ourselves

NCT06638892

RECRUITING Phase 1

Intestinal Microbiome Transplant in ALS

NCT07017946

RECRUITING NA

Improving Hypertension Control in Rheumatoid Arthritis

NCT05760898

RECRUITING NA

Development of a Pain Control Options Menu for IUD Insertion

NCT07278804

RECRUITING Phase 2

Allopregnanolone (Zuranolone) in Post-stroke Depression

NCT06759558

RECRUITING Phase 4

Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP

NCT07218211

RECRUITING NA

Weight Management After Cancer for Survivors in Rural Communities

NCT07426952

RECRUITING Phase 3

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

NCT06654882

RECRUITING NA

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

NCT06532773

RECRUITING NA

Yoga for Treatment of Overactive Bladder in Pediatric Patients

NCT05895045

RECRUITING NA

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

NCT07220005

RECRUITING

Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation

NCT07214350

RECRUITING NA

Virtual Reality Use for ICU Mobility

NCT07234201

RECRUITING Phase 2

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

NCT06816927

RECRUITING NA

Photon-counting CT in Chest Imaging

NCT07031336

RECRUITING NA

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

NCT07159269

RECRUITING Early Phase 1

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

NCT06731504

RECRUITING NA

Pediatrics Mobile CT

NCT07166926

RECRUITING NA

Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

NCT06983678

RECRUITING NA

Timing of Physician Rounds for Antepartum Patients

NCT07215507

RECRUITING NA

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

NCT06906627

RECRUITING NA

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

NCT06906640

RECRUITING NA

Eat Well Heart Failure

NCT07101289

RECRUITING Phase 4

Safety of RSV Preventive Monoclonal Antibody

NCT07158814

RECRUITING

Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging

NCT06177639

RECRUITING NA

Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy

NCT06972719

RECRUITING NA

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

NCT07089745

RECRUITING Phase 2

Repurposing Tilmanocept for Cardiac Sarcoidosis

NCT07159074

RECRUITING Phase 4

MAPS PrEP Van Study

NCT06908252

RECRUITING NA

Improving Needs Among Older Adults

NCT06588556

RECRUITING NA

Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)

NCT06428175

RECRUITING NA

Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery

NCT07117708

RECRUITING Phase 2

HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM

NCT06822972

RECRUITING NA

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

NCT06619405

RECRUITING NA

Pain With Dementia

NCT06854718

RECRUITING

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

NCT07050433

RECRUITING NA

4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800

NCT07024719

RECRUITING Phase 4

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

NCT06909565

RECRUITING NA

Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis

NCT06841562

RECRUITING NA

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

NCT06371768

RECRUITING NA

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

NCT06627764

RECRUITING NA

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

NCT06732375

RECRUITING NA

Engage Psychosocial Intervention for Cancer Symptoms

NCT06555588

RECRUITING NA

The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

NCT06765642

RECRUITING NA

DBT-P Treatment Study

NCT06963801

RECRUITING Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

NCT06962306

RECRUITING

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

NCT06971640

RECRUITING NA

Assessing Better Bottles for Babies

NCT06357299

RECRUITING NA

Urine Methylation Markers in UTUC

NCT06805630

RECRUITING NA

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

NCT06575712

RECRUITING NA

Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery

NCT06986967

RECRUITING

Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae

NCT06815536

RECRUITING NA

Opioids, Low Nicotine Cigarettes, and Chronic Pain

NCT06747871

RECRUITING NA

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

NCT06733012

RECRUITING NA

Role of Aging and Individual Variation in Exercise Training Responsiveness

NCT06471569

RECRUITING NA

Ultrasound Simulation Case-based Workshop Implementation and Impact Assessment

NCT06960837

RECRUITING NA

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

NCT06636721

RECRUITING Phase 2

Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

NCT06041789

RECRUITING NA

Collecting Outcomes and Managing Pain After Surgery

NCT03834818

RECRUITING NA

Olfactory Biopsies

NCT07021040

RECRUITING NA

OUD (Opioid Use Disorder) Target Trial

NCT06585709

RECRUITING

Rare Glycogen Storage Diseases Natural History Study

NCT06795152

RECRUITING

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

NCT06625684

RECRUITING Phase 4

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

NCT06576830

RECRUITING NA

GERD in Children With Cystic Fibrosis

NCT06617013

RECRUITING NA

Tolerability of an Anesthesia-free Tonometer Tip

NCT06585423

RECRUITING NA

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

NCT06538246

RECRUITING Phase 1

PK/PD of Digoxin in Infants With SVHD

NCT06613477

RECRUITING NA

Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?

NCT06471036

RECRUITING

Imaging Retinal Vasculature in Infant Eyes

NCT05558059

RECRUITING NA

Cancer and Mild Cognitive Impairment Dyadic Intervention

NCT05144516

RECRUITING

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

NCT06399302

RECRUITING NA

Bacterial Decolonization Within Dyads

NCT06541145

RECRUITING NA

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

NCT05945355

RECRUITING NA

Predictors of Pain in Sickle Cell Disease

NCT06139510

RECRUITING NA

Intervention to Improve Communication and Medication Adherence in Lupus

NCT06458075

RECRUITING Phase 1

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252

NCT06126744

RECRUITING NA

Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health

NCT06116422

RECRUITING NA

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study

NCT06333925

RECRUITING

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

NCT06141993

RECRUITING NA

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

NCT06087029

RECRUITING Phase 2

Personalized Nutrition to Improve Recovery in Trauma

NCT06065202

RECRUITING NA

Neuromodulation of Memory in Aging

NCT05460468

RECRUITING Phase 2

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial

NCT06069726

RECRUITING NA

SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)

NCT06177977

RECRUITING NA

Project humAn dieTary daTa rEtuRN

NCT06266689

RECRUITING

Trans-Rectal Ultrasound of the Female Pelvis for Real-Time MRI-US Fusion Based Needle Tracking

NCT05977621

RECRUITING

Optimize Pediatric OCT Imaging

NCT06139523

RECRUITING Early Phase 1

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

NCT05665465

RECRUITING NA

Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2

NCT06139458

RECRUITING NA

Oxygen Toxicity: Mechanisms in Humans

NCT05761756

RECRUITING NA

Mobile Neurofeedback for Low Back Pain

NCT05669027

RECRUITING NA

Testing a Device for Automatically TRacking Urine and STool in an Inpatient HCT Setting (Project TRUST)

NCT05520346

RECRUITING NA

The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions

NCT04140344

RECRUITING

COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children

NCT06164028

Phase Distribution

PhaseTrial count
Phase 1 94
Phase 2 45
Phase 3 9
Phase 4 56

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,129 US clinical trials across every stage of research activity. Of those, 781 studies are currently recruiting — about 69% of the sponsor's indexed portfolio — and 296 are already marked complete, representing roughly 26% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Duke University reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 139 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial