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Spinal Cord Injury clinical trials
Every US clinical trial registered for Spinal Cord Injury — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
100 US clinical trials · 38 currently recruiting
The research picture
Spinal Cord Injury has 100 registered US clinical trials, 38 of them open to new participants right now — about 38% of the total.
- 38
- recruiting participants now
- 38%
- of trials open to enrollment
- 5
- in Phase 3–4 (later-stage)
- 15
- top sponsor: VA Office of Research and Development
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Spinal Cord Injury Registry - North American Clinical Trials Network
Robert G. Grossman, MD
NCT00178724
Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic
VA Office of Research and Development
NCT06529094
The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study
AO Foundation, AO Spine
NCT06839300
Virtual Peer Coaching in Manual Wheelchair Skills
University of Pittsburgh
NCT06295146
Male Fertility Program
University of Miami
NCT01467869
mSCI: Mobile Health App for Veterans With SCI and Caregivers
University of Pittsburgh
NCT07269977
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
John D. Dingell VA Medical Center
NCT02922894
Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
Ohio State University
NCT07092293
Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia
VA Office of Research and Development
NCT05157282
SCI&U Peer Health Coaching Program for Individuals Newly Discharged From Inpatient Rehabilitation
University of Toronto
NCT06677905
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Northwell Health
NCT04755699
Clinical Outcome Assessment for AT & BCI
Shirley Ryan AbilityLab
NCT07407725
Neuromodulation After Spinal Cord Injury to Improve Limb Function
State University of New York at Buffalo
NCT06815601
Improve Dynamic Lateral Balance of Humans With SCI
Shirley Ryan AbilityLab
NCT02991248
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
University of Minnesota
NCT06410001
Cortical Recording and Stimulating Array Brain-Machine Interface
Michael Boninger
NCT01894802
Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait
Brooks Rehabilitation
NCT07164846
Exoskeleton and Spinal Cord Stimulation for SCI
Kessler Foundation
NCT03096197
Improving Bladder Function in SCI by Neuromodulation
University of California, Los Angeles
NCT02331979
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
North Florida Foundation for Research and Education
NCT04460872
Autonomic Effects of Stimulation in SCI
VA Office of Research and Development
NCT05664646
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Jason Carmel
NCT06867809
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
University of Wisconsin, Madison
NCT06840899
Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury
University of Mississippi Medical Center
NCT06274021
Exciflex for Chronic Wound Therapy
VA Office of Research and Development
NCT04887688
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
Medical University of South Carolina
NCT07179822
Reliability and Validity of the PReFS
Baylor University
NCT07280923
Testosterone and Neural Function
VA Office of Research and Development
NCT06130449
At-Home Genital Nerve Stimulation for SCI Bowel
MetroHealth Medical Center
NCT06836739
Self-balancing Personal Exoskeleton for SCI (WINY)
Wandercraft
NCT07222033
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury
HealthPartners Institute
NCT07384052
Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction
The University of Texas Health Science Center, Houston
NCT07213986
MEP Up-conditioning to Target Corticospinal Plasticity
Medical University of South Carolina
NCT06989905
Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury
Medical College of Wisconsin
NCT06723561
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Lineage Cell Therapeutics
NCT06841770
VR Mindfulness Training for Veterans With SCI
VA Office of Research and Development
NCT06587607
A Neuroprosthesis for Seated Posture and Balance
VA Office of Research and Development
NCT01474148
Leg Stretching Using an Exoskeleton on Demand for People With Spasticity
VA Office of Research and Development
NCT05926596
AIH-induced Walking Recovery After Subacute SCI
Spaulding Rehabilitation Hospital
NCT02632422
Integrated Tele-exercise for Individuals With Spinal Cord Injury
Drexel University
NCT05360719
C-Brace II Spinal Cord Injury
Shirley Ryan AbilityLab
NCT03930056
Electrical Stimulation for Continence After Spinal Cord Injury
Palo Alto Veterans Institute for Research
NCT02978638
Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury
MetroHealth Medical Center
NCT00583804
Intelligent Spine Interface, Clinical (ISI-C)
Rhode Island Hospital
NCT04302259
Perceived Barriers to Exercise in Individuals Living With Spinal Cord Injury
University of California, Irvine
NCT00786786
Magnetic Resonance Imaging Studies of Motor and Thought Processes
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001361
Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
Acorda Therapeutics
NCT00041717
Treadmill Training for Spinal Cord Injury
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00006429
Measurement of Autonomic Cardiovascular Integrity in Persons With SCI
James J. Peters Veterans Affairs Medical Center
NCT01758692
Power Over Pain (POP) Study
University of Washington
NCT01800604
Cardiovascular Disease Study
VA Office of Research and Development
NCT00857194
Maintenance of Shoulder Health and Function After Spinal Cord Injury
Rancho Research Institute
NCT02135978
Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury
Shriners Hospitals for Children
NCT01599455
Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
Elan Pharmaceuticals
NCT00047580
Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury
Oregon Health and Science University
NCT02878850
MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI
US Department of Veterans Affairs
NCT00561782
Neurofeedback Treatment of Pain in Persons With Spinal Cord Injury (SCI)
University of Washington
NCT00947999
A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences
James J. Peters Veterans Affairs Medical Center
NCT03023163
Re-Inventing Yourself After Spinal Cord Injury
Craig Hospital
NCT01633164
Treatment of Sleep-disordered Breathing in Patients With SCI
VA Office of Research and Development
NCT02830074
Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
Tanabe Pharma America
NCT04683848
Virtual Walking for Neuropathic Pain in Spinal Cord Injury
University of Alabama at Birmingham
NCT01884662
Wheelchair Mobility Assessment of Individuals With Spinal Cord Injury
University of Miami
NCT01204047
Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Northwestern University
NCT02325414
Improving Hand and Arm Function After Spinal Cord Injury (SCI)
University of Miami
NCT01143597
A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries
Vertex Pharmaceuticals Incorporated
NCT00500812
Use of an Oral Beta-2 Agonist in Persons With Spinal Cord Injury
US Department of Veterans Affairs
NCT00755079
Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers
St. Luke's Rehabilitation Institute
NCT02161913
Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury
Craig Hospital
NCT02392052
Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury
University of Michigan
NCT00735670
Safety and Efficacy of L-NAME and Midodrine to Increase MAP
US Department of Veterans Affairs
NCT00835224
Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia
Craig Hospital
NCT01815554
Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial
Brigham and Women's Hospital
NCT02218203
12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Northwestern University
NCT02025179
Fenofibrate Treatment in SCI
VA Office of Research and Development
NCT02455336
Experimental Evaluation of Wheelchair-Mounted Robotic Arms
University of South Florida
NCT01652352
Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation
The Cleveland Clinic
NCT01539109
Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.
Craig Hospital
NCT00320281
Development and Feasibility of an Internet Intervention for Adults With Spinal Cord Injury to Prevent Pressure Ulcers
University of Virginia
NCT01885962
Development of Low Cost Devices to Increase Access to Treadmill Training
Shirley Ryan AbilityLab
NCT02560506
Electrical Control of Bladder in Spinal Cord Injury Patients
US Department of Veterans Affairs
NCT00011570
Virtual Sailing Simulator in Individuals With Spinal Cord Injury
Hugo W. Moser Research Institute at Kennedy Krieger
NCT01491789
Effects of Salsalate on Prandial-Induced Vascular Inflammation After Spinal Cord Injury (SCI)
University of Miami
NCT01201759
Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury
Spaulding Rehabilitation Hospital
NCT03267212
Veteran-Centered Outcomes Using Qualitative and Quantitative Methods
US Department of Veterans Affairs
NCT00333580
Testosterone and Long Pulse Stimulation After SCI
VA Office of Research and Development
NCT03345576
Effects of Acute SCI on Colonic Motility & Tone
US Department of Veterans Affairs
NCT00013312
Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)
Thomas J. Schnitzer
NCT00826228
Ventilatory Support to Improve Exercise Training in High Level Spinal Cord Injury
Spaulding Rehabilitation Hospital
NCT02865343
Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury
VA Office of Research and Development
NCT04971408
Treating Cognitive Deficits in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
NCT03037879
24hr Effects of Tiotropium Bromide in Tetraplegia
James J. Peters Veterans Affairs Medical Center
NCT02586649
Identify Training Strategies for Progressing Exoskeleton Users Towards Everyday Functional Ambulation
Shirley Ryan AbilityLab
NCT02104622
Restoring Arm and Hand Function With Non-invasive Spinal Stimulation
NeuroEnabling Technologies
NCT01906424
Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.
VA Office of Research and Development
NCT05008484
Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury
Kessler Foundation
NCT01355549
Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury
University of Louisville
NCT02037620
Home/Work, Community Mobility Skills in the ReWalk Exoskeleton in Persons With SCI
James J. Peters Veterans Affairs Medical Center
NCT02118194
Neuromodulation Techniques After SCI
VA Office of Research and Development
NCT04241250
Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury
University of Louisville
NCT02154412
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 17 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Spinal Cord Injury Trial Landscape
ClinicalTrials.gov lists 100 US studies indexed under Spinal Cord Injury, and 38 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Spinal Cord Injury shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 26 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Spinal Cord Injury is led by VA Office of Research and Development with 15 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Spinal Cord Injury?
PlainTrial tracks 100 US clinical trials for Spinal Cord Injury, of which 38 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Spinal Cord Injury?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.