VA Office of Research and Development
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).
VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.
VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.
Top-decile sponsor footprint
VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,668 total, page 3 of 34
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
NCT06068491
A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
NCT05563766
Cognitive Control Training for Extinction in PTSD
NCT06629064
Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
NCT05888233
PSMA PET for the Staging and Management of Hepatocellular Carcinoma
NCT07019844
mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders
NCT06204705
Feasibility and Safety of a Portable Exoskeleton to Improve Mobility in Parkinson's Disease
NCT06028529
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
NCT06162741
Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke
NCT06400186
Suicide Specific Rumination in Veterans
NCT06481033
RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain
NCT05963607
Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain
NCT06058624
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
NCT05628324
Biomechanical Validation of the CATT
NCT06013878
Multi-speed Ergonomic Wheelchair
NCT05776030
Evaluating Treatments for Suicidal Veterans With PTSD
NCT05974631
Overcontrol and Suicide in PTSD
NCT06355284
Telehealth Delivered Home-based Walking for Vets With Peripheral Artery Disease
NCT06033924
Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond
NCT04109027
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
NCT05880108
Pupil-Indexed Noninvasive Neuromodulation
NCT06282406
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
NCT05593497
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
NCT05931276
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
NCT05647044
Weight Loss and ExeRcise
NCT06322030
Web-based Program to Improve Self-management Among Veterans-caregiver Dyads
NCT06001541
Stimulation for Bowel Emptying
NCT06078176
A Computerized Depression Intervention in Veterans
NCT06217198
Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery
NCT05912257
Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions
NCT06288438
Empagliflozin Treatment in Kidney Transplant Recipients
NCT06013865
Spinal Cord Associative Plasticity for ALS
NCT06172621
A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings
NCT06404970
MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI
NCT06138054
Gerofit and Cognition
NCT06107842
Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
NCT05858346
Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations
NCT06106984
Testosterone and Neural Function
NCT06130449
Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans
NCT06309264
A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation
NCT06218238
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
NCT05937854
Brain Balance Study
NCT05714150
Expressive Writing on Minority Stressors Among Sexual Minority Veterans
NCT05897021
A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans
NCT05995678
VA Transitional Pain Service Study
NCT06223503
Repositioning Immunotherapy in VetArans With Lung Cancer
NCT06275360
Active AMD Study to Improve Function in Veterans
NCT05932069
Behavioral Activation for Independence in Older Veterans
NCT05493241
Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints
NCT05776056
NAFLD Clinical Care Pathway
NCT06671886
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 89 |
| Phase 2 | 147 |
| Phase 3 | 55 |
| Phase 4 | 69 |
Therapeutic Areas
What is open in the VA Office of Research and Development pipeline
291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).
Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).
Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
VA Office of Research and Development: open-pipeline peers nationwide
Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,668 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Duke University · 1,725 trials · 11% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- Washington University School of Medicine · 1,502 trials · 14% recruiting
Sponsors near 17% open enrollment (± trial volume)
- University of South Florida · 17% recruiting · 252 trials
- ImmunityBio · 17% recruiting · 46 trials
- Old Dominion University · 17% recruiting · 23 trials
- Texas Tech University · 17% recruiting · 69 trials
Related
What to do with this VA Office of Research and Development page
1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.
- 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.