VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 1 of 34

RECRUITING NA

I-SLEPT: Integrated Sleep and Life Engagement Program for Transitions

NCT07317336

RECRUITING NA

Prediction Augmented Screening Initiative

NCT06538636

RECRUITING Phase 4

Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

NCT06953726

RECRUITING NA

Tailor VHA HH Bundle for Acute Mental Health Care

NCT07607145

RECRUITING Phase 2

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

NCT07118839

RECRUITING NA

Implementing a Mobile Health Application for Women Veterans With Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0

NCT07219433

RECRUITING NA

Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0

NCT07215572

RECRUITING NA

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

NCT07216261

RECRUITING NA

Health Promotion With Targeted Exercise Intervention for Decreasing Fall Risk and Inactivity in Aging Veterans With Obesity and Signs of Sarcopenia

NCT07206368

RECRUITING

Cognitive-Sensorimotor Function in Long-COVID

NCT06850350

RECRUITING Phase 1

Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma

NCT05842174

RECRUITING NA

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

NCT07190365

RECRUITING NA

Inclined Versus Standard Exercise for COPD Patients

NCT06749262

RECRUITING NA

Advancing Decisions About Virtual Service Encounters

NCT06539988

RECRUITING Phase 4

Atomoxetine and Executive Function in PTSD

NCT06573970

RECRUITING NA

Improving Cognitive Rehabilitation Outcomes

NCT07055633

RECRUITING

Mobile Technology to Measure Knee Health in Osteoarthritis

NCT07580222

RECRUITING NA

Improving Dietary Quality and Social Engagement Through a Virtual Nutrition and Teaching Kitchen Intervention Among Older Veterans With Impaired Mobility

NCT06726083

RECRUITING NA

Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease

NCT07210580

RECRUITING NA

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

NCT07010757

RECRUITING NA

Cognitive Rehabilitation for Veterans With PNES

NCT07316543

RECRUITING NA

Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection

NCT06803329

RECRUITING Phase 2

Ketamine for Veterans With Parkinson's Disease

NCT06231563

RECRUITING NA

Non-invasive VNS for Parkinson's Gait

NCT06562569

RECRUITING Phase 1

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

NCT06681220

RECRUITING NA

Improving Veteran Referral to Cardiac Rehabilitation

NCT07079358

RECRUITING NA

Leg Stretching Using an Exoskeleton on Demand for People With Spasticity

NCT05926596

RECRUITING NA

Randomized Clinical Trial for Ewing Amputation in the VA

NCT05437562

RECRUITING NA

CBT-CP for Veterans With SMI

NCT06758414

RECRUITING

Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

NCT06857851

RECRUITING Phase 4

Randomized Trial of SGLT2i in Heart Transplant Recipients

NCT06625073

RECRUITING Phase 1

Home-based Vision Therapy

NCT06886737

RECRUITING NA

Targeted Telerehabilitation Following Curative Intent Therapy of Lung Cancer

NCT05179408

RECRUITING NA

Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach

NCT07356492

RECRUITING Phase 3

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

NCT06488144

RECRUITING Phase 1

EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

NCT05467748

RECRUITING Phase 2

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

NCT06419439

RECRUITING NA

Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial

NCT07149870

RECRUITING

Driver Training After Stroke

NCT06672107

RECRUITING NA

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

NCT06671613

RECRUITING Phase 4

Better Options for Chronic Cancer Pain

NCT06574009

RECRUITING Phase 3

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

NCT07039175

RECRUITING NA

Suicide Prevention After Community Care Discharge

NCT06596044

RECRUITING Phase 2

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

NCT06520098

RECRUITING NA

Personalized Approach to Healthy Use and Recovery (PATH) Trial

NCT06580457

RECRUITING NA

Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual Violence

NCT06746740

RECRUITING NA

NightWare and Cardiovascular Health in Veterans With PTSD

NCT06419959

RECRUITING NA

Mobile Intervention for Suicidal Thoughts

NCT06593379

RECRUITING Phase 1

DRonabinol Treatment of OSA

NCT06477952

RECRUITING NA

SMART Therapist Training: A Hybrid Factorial-SMART Design

NCT07010770

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.