Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
PTSD: early-phase trial registry
77 of 155 indexed PTSD trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #72 of 28,707 conditions by registered trial count.
155 US clinical trials · 77 currently recruiting · #72 of 28,707 conditions by registered trial count
PTSD: 155 US clinical trials tracked, 77 recruiting.
PTSD is the subject of 155 registered US clinical trials on ClinicalTrials.gov, 77 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 28 of these trials.
Enrollment posture brief
Registry condition ptsd
OPEN 77 | RECR 50% | LATE 10 | EARLY 29 | RANK #72 | SPON 28
Volume-matched condition peers
Nearest open-share peer: Alzheimer Disease (50% recruiting · 312 trials)
PTSD lists 77 open slots (50% of 155 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for PTSD on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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PTSD is recruiting above its size-band peers.
77 of 155 indexed trials (49.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates PTSD research.
VA Office of Research and Development accounts for 28 of 155 trials (18.1%). 88 distinct sponsors appear on at least one study for this condition label.
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Typical PTSD enrolment sits around 75 participants.
Median target enrolment is 75 among the 155 trials that report a genuine target (sentinel values excluded). 89 of those (57.4%) plan for fewer than 100 participants.
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PTSD research is mostly interventional.
143 interventional and 12 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
155 total, page 1 of 4
Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder
University of Chicago
NCT06479447
The ED-AWARENESS-2 Trial
Washington University School of Medicine
NCT05534243
REstoring Mental Health Through COmmUnity-based Psychological Services in New York City
George Washington University
NCT04913766
PTSD Treatment for Incarcerated Men and Women: AV
University of Wisconsin, Madison
NCT07283757
PTSD Screening in Pregnant Black Women
Emory University
NCT06522022
AIMS Medical Outcomes Study
Advanced Integrative Medical Science Institute
NCT04512755
Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
University of Michigan
NCT05457985
A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems
University of Washington
NCT05632770
Treatments for Insomnia in Veterans With PTSD
VA Office of Research and Development
NCT05194930
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
Stanford University
NCT06367764
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
Medical University of South Carolina
NCT06856057
Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset
Rush University Medical Center
NCT05700279
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
The University of Texas Health Science Center at San Antonio
NCT07176273
Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center
Baylor Research Institute
NCT06210711
Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans
The University of Texas Health Science Center, Houston
NCT05368987
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
VA Salt Lake City Health Care System
NCT06300255
COPEWeb Training for Providers
VA Office of Research and Development
NCT05812131
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
Boston University
NCT05486793
A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel
Weill Medical College of Cornell University
NCT03803332
Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
University of Rochester
NCT06956781
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
NCT06624137
Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial
VA Office of Research and Development
NCT07010757
Oxytocin to Enhance Integrated Treatment for AUD and PTSD
Medical University of South Carolina
NCT04523922
Neural Connectivity During Therapy for Adolescent PTSD
The University of Texas Health Science Center at San Antonio
NCT05423444
Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults
University of Nebraska
NCT05269459
Project Safe Guard-Trauma
University of Colorado, Denver
NCT06876740
Safe Mothers, Safe Children Initiative
New York University
NCT04752618
Non-Inferiority Trial of TrIGR for PTSD
VA Office of Research and Development
NCT05789329
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
Medical University of South Carolina
NCT07390786
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Medical University of South Carolina
NCT07372586
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
University of Massachusetts, Worcester
NCT06278922
Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children
New York University
NCT06262178
A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans
VA Office of Research and Development
NCT05995678
Psychotherapy Effects on Reward Processing in PTSD
University of Texas at Austin
NCT06096740
Cognitive Control Training for Extinction in PTSD
VA Office of Research and Development
NCT06629064
The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD
University of Alabama, Tuscaloo
NCT06144203
Treatments in Women Veterans With Insomnia and PTSD
VA Office of Research and Development
NCT05683132
Cognitive Processing Therapy (CPT) Memory Support (MS) Study
Boston University
NCT05310097
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Ohio State University
NCT06285708
Exercise and Emotional Learning in Posttraumatic Stress Disorder
Christal L Badour
NCT06127342
Vagal Nerve Stimulation in mTBI
VA Office of Research and Development
NCT04437498
Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder
White River Junction Veterans Affairs Medical Center
NCT05637879
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
University of Rhode Island
NCT07217795
Enhancing Rehabilitation for Veterans With Serious Mental Illness
VA Office of Research and Development
NCT06586164
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Duke University
NCT05120635
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
Reset Medical and Wellness Center
NCT07473505
Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma
Paul Crawford
NCT05516862
Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy
Montefiore Medical Center
NCT03755401
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
University of Illinois at Chicago
NCT06261463
Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
VA Office of Research and Development
NCT05380050
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 22 |
| Phase 3 | 5 |
| Phase 4 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on PTSD records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on PTSD trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this PTSD page
155 registered trials, 77 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 77 PTSD trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most PTSD trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This PTSD condition card totals 155 registered trials; most-linked intervention Cognitive Processing Therapy; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.