Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 1 of 10
Get With the Guidelines-Stroke Registry
American Heart Association
NCT02693223
Stroke Recovery Initiative - Registry for Stroke Research Studies
University of California, San Francisco
NCT03318432
Stroke Thrombectomy and Aneurysm Registry
Medical University of South Carolina
NCT04994756
International Care Bundle Evaluation in Cerebral Hemorrhage Research
Region Skane
NCT06429332
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Icahn School of Medicine at Mount Sinai
NCT04045665
Transitions of Care for Stroke Patients
Kiwon Lee MD
NCT06011720
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
Population Health Research Institute
NCT03968393
The CONFORM Pivotal Trial
Conformal Medical
NCT05147792
Minocycline in Stroke Study at Maimonides
Joyce Chen
NCT07237048
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
University of Cincinnati
NCT05911568
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
State University of New York at Buffalo
NCT00682695
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Zeenat Qureshi Stroke Institute
NCT06402968
Human-like Robotic Controllers for Enhanced Motor Learning
Shirley Ryan AbilityLab
NCT04578665
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
DiaMedica Therapeutics
NCT05065216
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
University of Cincinnati
NCT05338697
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
W.L.Gore & Associates
NCT03821129
Beacon Tip Sizing Catheter and Slip-Cath Beacon Tip Catheter Study
Cook Research Incorporated
NCT06986954
CoMind Early Feasibility Study
CoMind Technologies Limited
NCT06368648
Reducing Blood Pressure in Patients With High Cardiovascular Risk
University of Southern California
NCT05937685
Compass 3: A Novel Transition Program to Reduce Disability After Stroke
Washington University School of Medicine
NCT07069660
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
University of South Carolina
NCT05370014
Neurologic Stem Cell Treatment Study
MD Stem Cells
NCT02795052
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
NCT06615973
Cognition and Imaging With Tigertriever
Rapid Medical
NCT05531461
Inpatient Stroke Recovery Using Sensors
Shirley Ryan AbilityLab
NCT04219670
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)
Temple University
NCT06530693
StrokeCog-BBB to Study Cognitive Outcomes Following Stroke
Stanford University
NCT06116630
Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
University of Maryland, College Park
NCT06405594
ReadMap: Reading in Stroke Alexia and Typical Aging
Georgetown University
NCT06700005
Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients
EMVision Medical Devices
NCT06999122
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Yale University
NCT05907629
A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
University of Wisconsin, Madison
NCT02098265
SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes
Columbia University
NCT06397937
C-STAR Movement Database
Shirley Ryan AbilityLab
NCT05471375
Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
University of California, Los Angeles
NCT05518305
Traumatic Brain Injury and Stroke Long Term Outcome
Centre for Neuro Skills
NCT03399929
Efficacy and Sustainability of a Carepartner-Integrated Telerehabilitation Program for Persons With Stroke
Emory University
NCT06655402
Telerehabilitation In The Home After Stroke
University of California, Los Angeles
NCT06682429
Pilot/Pivotal Study of DBS+Rehab After Stroke
Enspire DBS Therapy
NCT05701280
The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation
State University of New York - Upstate Medical University
NCT05012605
Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing
University of Alabama at Birmingham
NCT06943586
The Beneficial Effects of Naps on Motor Learning
National Institute of Neurological Disorders and Stroke (NINDS)
NCT04312126
HIT-Stroke Trial 2
University of Cincinnati
NCT06268041
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
Hackensack Meridian Health
NCT05651945
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
International Consortium of Circulatory Assist Clinicians
NCT06039176
Locomotor Recovery and Compensation Post-stroke (LRC)
Indiana University
NCT05081713
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
Massachusetts General Hospital
NCT07414732
Language Processing and TMS
Medical College of Wisconsin
NCT05425615
EMPOWER: Effects of Weight Loss and Exercise Post-stroke
Medical University of South Carolina
NCT05901675
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.