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NCT06932237 · ClinicalTrials.gov registry record

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

A clinical trial of Long COVID and Neuro-PASC, sponsored by VA Office of Research and Development.

Recruiting
Registry status
200
Enrollment target
2
Study locations

NCT06932237: Recruiting study of Long COVID and Neuro-PASC, sponsored by VA Office of Research and Development.

NCT06932237 is a study of Long COVID and Neuro-PASC that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 200 participants, below the 2,184-participant average among 50 other Long COVID trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06932237, a study of Long COVID and Neuro-PASC, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
200 participants
Enrollment target
2
Study locations

Study Summary

Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of great concern to Veterans. The investigators' research seeks to advance understanding of the long-term effects of COVID-19 on neuropsychiatric and neurological functions, identifying clinically relevant biomarkers and directions for developing and testing therapeutic interventions. To accomplish these objectives the investigators are conducting a longitudinal study at two VA medical centers to: 1) assess and monitor cognitive function and psychiatric symptoms in Veterans post-COVID; 2) evaluate biomarkers of inflammation and signaling pathways associated with viral infection and neuropsychiatric function; and 3) integrate neuropsychiatric and neurological findings with biological data to identify biomarkers and clinical endpoints associated with disease progression or severity, as well as those for promoting brain repair and attenuating those symptoms.

Primary Outcome

A nine-item self-report questionnaire designed to assess fatigue as a symptom of a variety of different chronic conditions and disorders.

Conditions Studied

Study Locations (2)

Oregon

  • VA Portland Health Care System, Portland, OR - Portland

Tennessee

  • James H. Quillen VA Medical Center, Mountain Home, TN - Mountain Home

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2025-02-20
Est. Completion 2028-03-31
VA Office of Research and Development

1,668 total trials

What NCT06932237 shows while recruiting

NCT06932237 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 2,184-participant average among 50 other Long COVID trials with a reported enrollment target (91% lower).

The record links to 2 conditions, with Long COVID appearing as the primary indexed condition, and to 0 interventions.

NCT06932237 reports a single indexed study location in Oregon, Tennessee.

Frequently Asked Questions

What is clinical trial NCT06932237 about?

NCT06932237 is a clinical study titled "Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans". Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of great concern to Veterans. The investigators' research seeks to advance understanding of the long-term effects of COVID-19 on neuropsychiatric and neurological functions, identifying clinically relevant b...

What is the current status of trial NCT06932237?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2025-02-20. Estimated completion is 2028-03-31.

What conditions does trial NCT06932237 study?

This clinical trial studies the following conditions: Long COVID, Neuro-PASC.

Who is sponsoring clinical trial NCT06932237?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06932237 being conducted?

This trial has 2 study locations across Oregon, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Long COVID

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06932237's enrollment target sits among peer trials

200 16th of 50 higher than 34 of 50 other Long COVID trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Long COVID trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06932237, the US trial registry maintained by the National Library of Medicine. NCT06932237 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.