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NCT06586164 · ClinicalTrials.gov registry record · NA

Enhancing Rehabilitation for Veterans With Serious Mental Illness

A NA study of Schizophrenia and Bipolar Disorder, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT06586164: Recruiting NA study of Schizophrenia and Bipolar Disorder, sponsored by VA Office of Research and Development.

NCT06586164 is a NA study of Schizophrenia and Bipolar Disorder that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 80 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06586164, a NA study of Schizophrenia and Bipolar Disorder, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chronic functional disability, and impaired outcomes, causing a significant strain on support networks and the VA healthcare system. This study aims to introduce an innovative mental health therapy, Targeted Cognitive Training (TCT), to Veterans struggling with serious mental illnesses (SMI). TCT works to improve basic sensory information processing and, ultimately, clinical, cognitive, and psychosocial functioning. By using EEG biomarkers to identify Veterans with SMI receiving care within VA Psychosocial Rehabilitation and Recovery Centers who are most likely to benefit from this treatment, and by understanding how best to implement this therapy, the investigators hope to enhance care and improve life quality for Veterans with SMI.

Primary Outcome

Change from baseline clinical symptoms Positive and Negative Syndrome Scale (PANSS) The Positive and Negative Syndrome Scale (PANSS) will used to evaluate the presence, absence and severity of Positive, Negative and General Psychopathology symptoms of SZ. The PANSS is a 30-item scale arranged as 7 positive symptom subscale items, 7 negative symptom subscale items, and 16 general psychopathology symptom items. Each item has a definition and a basis for rating. All 30 items are rated on a 7-point

Conditions Studied

Schizophrenia Bipolar Disorder PTSD Schizoaffective Disorder Psychosis Serious Mental Illness

Interventions

  • BEHAVIORAL Targeted Cognitive Training

Study Locations (1)

California

  • VA San Diego Healthcare System, San Diego, CA - San Diego

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2025-02-25
Est. Completion 2028-10-31
Phase NA
VA Office of Research and Development

1,668 total trials

What NCT06586164 shows while recruiting

NCT06586164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (63% lower).

The record links to 6 conditions, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Targeted Cognitive Training is the first listed.

NCT06586164 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06586164 about?

NCT06586164 is a clinical study titled "Enhancing Rehabilitation for Veterans With Serious Mental Illness". This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chron...

What is the current status of trial NCT06586164?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-02-25. Estimated completion is 2028-10-31.

What conditions does trial NCT06586164 study?

This clinical trial studies the following conditions: Schizophrenia, Bipolar Disorder, PTSD, Schizoaffective Disorder, Psychosis.

What interventions are being tested in trial NCT06586164?

The interventions under investigation include: Targeted Cognitive Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT06586164?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06586164 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Schizophrenia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06586164's enrollment target sits among peer trials

80 161st of 315 higher than 151 of 315 other Schizophrenia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06586164

Source: ClinicalTrials.gov NCT06586164, the US trial registry maintained by the National Library of Medicine. NCT06586164 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.