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NCT06845046 · ClinicalTrials.gov registry record · NA
A Study to Improve Skeletal Muscle in Veterans With HIV
A NA study of Obesity and HIV, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06845046: Recruiting NA study of Obesity and HIV, sponsored by VA Office of Research and Development.
NCT06845046 is a NA study of Obesity and HIV that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 70 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06845046, a NA study of Obesity and HIV, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to physical function decline, frailty, disability, and cardiometabolic diseases such as diabetes and cardiovascular disease. In the investigators current Merit supported cohort, the investigators found that 36% of Veterans with treated HIV and obesity have "myosteatotic type obesity". Based on the investigators findings, the investigators have designed a multipronged integrated intervention that combines: 1) dietary replacement of saturated with unsaturated fats; 2) administration of L-carnitine and omega-3 fatty acid supplementation; and 3) targeted resistance exercise training.
Primary Outcome
CT quantified abdominal skeletal muscle density
Interventions
- OTHER Control Diet
- DIETARY_SUPPLEMENT w-3 fatty acid
- DIETARY_SUPPLEMENT L-carnitine
Study Locations (1)
Tennessee
- Tennessee Valley Healthcare System Nashville Campus, Nashville, TN - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-07-15 |
| Est. Completion | 2029-06-29 |
| Phase | NA |
What NCT06845046 shows while recruiting
NCT06845046 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Control Diet is the first listed.
NCT06845046 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT06845046 about?
NCT06845046 is a clinical study titled "A Study to Improve Skeletal Muscle in Veterans With HIV". The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to physical function decline, frailty, disability, and cardiometabolic diseases...
What is the current status of trial NCT06845046?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2025-07-15. Estimated completion is 2029-06-29.
What conditions does trial NCT06845046 study?
This clinical trial studies the following conditions: Obesity, HIV.
What interventions are being tested in trial NCT06845046?
The interventions under investigation include: Control Diet (OTHER), w-3 fatty acid (DIETARY_SUPPLEMENT), L-carnitine (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06845046?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06845046 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06845046's enrollment target sits among peer trials
70 595th of 1053 higher than 449 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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