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NCT05931289 · ClinicalTrials.gov registry record · Phase 2

Suicide Risk Interventions

A Phase 2 study of Suicide, sponsored by VA Office of Research and Development.

Recruiting
Registry status
Phase 2
Development phase
136
Enrollment target
1
Study location

NCT05931289 is a Phase 2 study of Suicide that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 136 participants, below the 6,988-participant average among 92 other Suicide trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05931289, a Phase 2 study of Suicide, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
Phase 2
Development phase
136 participants
Enrollment target
1
Study location

Study Summary

The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 female and male Veterans who have been hospitalized for suicide risk and randomly assign them to receive one of two psychotherapy treatments for suicide risk after they leave the hospital. The goals of this study are to examine if a) a longer psychotherapy causes greater improvements in coping skills and reductions in negative suicidal thinking, b) a longer psychotherapy is more effective in reducing suicide risk, and c) if Veterans with a history of multiple suicide attempts are more likely to benefit from the longer psychotherapy. Additionally, this study will use magnetic resonance imaging (MRI) neuroimaging scans of Veterans shortly after they leave the hospital and again 4- and 12-months later. This study will explore a) if brain markers can predict suicide attempts, b) if brain markers change over time as suicide risk changes, and c) if brain markers change differently for the two types of psychotherapy.

Conditions Studied

Suicide

Interventions

  • BEHAVIORAL Enhanced Crisis Response Planning (ECRP)
  • BEHAVIORAL Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)

Study Locations (1)

Massachusetts

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA - Boston

Trial Details

FieldValue
Enrollment Target 136 participants
Start Date 2025-03-03
Est. Completion 2027-12-31
Phase Phase 2

Sponsor

VA Office of Research and Development

1,668 total trials

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What the Registry Record Tells You About NCT05931289

The ClinicalTrials.gov registry entry for NCT05931289 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 6,988-participant average among 92 other Suicide trials with a reported enrollment target (98% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Suicide appearing as the primary indexed condition, and to 2 interventions - of which Enhanced Crisis Response Planning (ECRP) is the first listed.

NCT05931289 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05931289 about?

NCT05931289 is a clinical study titled "Suicide Risk Interventions". The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 f...

What is the current status of trial NCT05931289?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 136 participants. The study started on 2025-03-03. Estimated completion is 2027-12-31.

What conditions does trial NCT05931289 study?

This clinical trial studies the following conditions: Suicide.

What interventions are being tested in trial NCT05931289?

The interventions under investigation include: Enhanced Crisis Response Planning (ECRP) (BEHAVIORAL), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT05931289?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05931289 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.