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NCT05931289 · ClinicalTrials.gov registry record · Phase 2
Suicide Risk Interventions
A Phase 2 study of Suicide, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 136
- Enrollment target
- 1
- Study location
NCT05931289: Recruiting Phase 2 study of Suicide, sponsored by VA Office of Research and Development.
NCT05931289 is a Phase 2 study of Suicide that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 136 participants, below the 6,988-participant average among 92 other Suicide trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05931289, a Phase 2 study of Suicide, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 136 participants
- Enrollment target
- 1
- Study location
Study Summary
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 female and male Veterans who have been hospitalized for suicide risk and randomly assign them to receive one of two psychotherapy treatments for suicide risk after they leave the hospital. The goals of this study are to examine if a) a longer psychotherapy causes greater improvements in coping skills and reductions in negative suicidal thinking, b) a longer psychotherapy is more effective in reducing suicide risk, and c) if Veterans with a history of multiple suicide attempts are more likely to benefit from the longer psychotherapy. Additionally, this study will use magnetic resonance imaging (MRI) neuroimaging scans of Veterans shortly after they leave the hospital and again 4- and 12-months later. This study will explore a) if brain markers can predict suicide attempts, b) if brain markers change over time as suicide risk changes, and c) if brain markers change differently for the two types of psychotherapy.
Primary Outcome
The SITBI-R is a structured interview assessment of the frequency, intensity, and characteristics of self-injurious thoughts and behaviors. The SITBI-R will be used to assess lifetime history of suicide attempts at baseline and the number, approximate date, method, and injuries resulting from any suicide attempts occurring during the 12-month period following discharge via administrations at the 2, 4, 8, and 12-month post-discharge assessments.
Conditions Studied
Interventions
- BEHAVIORAL Enhanced Crisis Response Planning (ECRP)
- BEHAVIORAL Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
Study Locations (1)
Massachusetts
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 136 participants |
| Start Date | 2025-03-03 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 2 |
What NCT05931289 shows while recruiting
NCT05931289 is an interventional study that assigns participants to a tested intervention. The registered 136 participants enrollment target is mid-sized for trials with a published cap, below the 6,988-participant average among 92 other Suicide trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Suicide appearing as the primary indexed condition, and to 2 interventions - of which Enhanced Crisis Response Planning (ECRP) is the first listed.
NCT05931289 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05931289 about?
NCT05931289 is a clinical study titled "Suicide Risk Interventions". The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 f...
What is the current status of trial NCT05931289?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 136 participants. The study started on 2025-03-03. Estimated completion is 2027-12-31.
What conditions does trial NCT05931289 study?
This clinical trial studies the following conditions: Suicide.
What interventions are being tested in trial NCT05931289?
The interventions under investigation include: Enhanced Crisis Response Planning (ECRP) (BEHAVIORAL), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05931289?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05931289 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Suicide
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05931289's enrollment target sits among peer trials
136 41st of 92 higher than 52 of 92 other Suicide trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Suicide trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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