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NCT06548113 · ClinicalTrials.gov registry record · NA
Sensory Synchronized Imaging and Neuromodulation
A NA study of Major Depressive Disorder, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 1
- Study location
NCT06548113: Recruiting NA study of Major Depressive Disorder, sponsored by VA Office of Research and Development.
NCT06548113 is a NA study of Major Depressive Disorder that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 250 participants, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06548113, a NA study of Major Depressive Disorder, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to better understand the relationship between the type of brain stimulation used and how it changes brain activity in adult military Veterans. The goal is to use this understanding to develop new, personalized brain stimulation. The investigators evaluate brain changes from different types of transcranial magnetic brain stimulation (TMS).
Primary Outcome
Change in the TMS-EEG measure will be assessed before, during, and after each TMS session. Specifically, the difference in size of the evoked response after a single TMS pulse in the frontoparietal region will be quantified in microVolts and compared between standard TMS and sensory-entrained TMS (se-TMS).
Conditions Studied
Interventions
- DEVICE TMS
Study Locations (1)
California
- VA Palo Alto Health Care System, Palo Alto, CA - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2025-04-01 |
| Est. Completion | 2029-10-01 |
| Phase | NA |
What NCT06548113 shows while recruiting
NCT06548113 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (34% lower).
The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 1 intervention - of which TMS is the first listed.
NCT06548113 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06548113 about?
NCT06548113 is a clinical study titled "Sensory Synchronized Imaging and Neuromodulation". The purpose of this research study is to better understand the relationship between the type of brain stimulation used and how it changes brain activity in adult military Veterans. The goal is to use this understanding to develop new, personalized brain stimulation. The investigators evaluate brain ...
What is the current status of trial NCT06548113?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2025-04-01. Estimated completion is 2029-10-01.
What conditions does trial NCT06548113 study?
This clinical trial studies the following conditions: Major Depressive Disorder.
What interventions are being tested in trial NCT06548113?
The interventions under investigation include: TMS (DEVICE).
Who is sponsoring clinical trial NCT06548113?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06548113 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depressive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06548113's enrollment target sits among peer trials
250 60th of 282 higher than 223 of 282 other Major Depressive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depressive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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