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NCT05553353 · ClinicalTrials.gov registry record · NA
Dosing rTMS for Depression Post-SCI
A NA study of Depression and Spinal Cord Injuries, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05553353 is a NA study of Depression and Spinal Cord Injuries that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 24 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05553353, a NA study of Depression and Spinal Cord Injuries, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population. Depression post-SCI impacts an individuals' quality of life and recovery. It has been reported that among Veterans with an SCI, those without depression live longer than those with depression. Thus, depression must be treated appropriately. Repetitive transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression, but dosing is based on a motor response or movement in the thumb. Over half of individuals with SCI have some degree of arm or hand impairment, so these individuals might not be eligible for rTMS, or they may receive the wrong dose. This study proposes clinical trial in individuals with depression post-SCI to assess the anti-depressant effect of a novel technique to dose rTMS that does not require a motor response in the thumb. By gaining a better understanding of the application of rTMS for depression post-SCI, the investigators aim to advance the rehabilitative care of Veterans.
Conditions Studied
Interventions
- DEVICE repetitive transcranial magnetic stimulation--Active
- DEVICE repetitive transcranial magnetic stimulation--Sham
Study Locations (1)
South Carolina
- Ralph H. Johnson VA Medical Center, Charleston, SC - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-03-31 |
| Est. Completion | 2027-10-29 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05553353
The ClinicalTrials.gov registry entry for NCT05553353 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which repetitive transcranial magnetic stimulation--Active is the first listed.
NCT05553353 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.
Frequently Asked Questions
What is clinical trial NCT05553353 about?
NCT05553353 is a clinical study titled "Dosing rTMS for Depression Post-SCI". Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population. Depression post-SCI impacts an individuals' quality of life and recovery. It has been reported that among Veterans with an SCI, those without ...
What is the current status of trial NCT05553353?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2025-03-31. Estimated completion is 2027-10-29.
What conditions does trial NCT05553353 study?
This clinical trial studies the following conditions: Depression, Spinal Cord Injuries, Depressive Disorder, Major.
What interventions are being tested in trial NCT05553353?
The interventions under investigation include: repetitive transcranial magnetic stimulation--Active (DEVICE), repetitive transcranial magnetic stimulation--Sham (DEVICE).
Who is sponsoring clinical trial NCT05553353?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05553353 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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