National Institute of Mental Health (NIMH)

343 total trials 42 currently recruiting 256 completed

National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.

Trial Pipeline

343 total, page 5 of 7

COMPLETED Phase 2

PET Imaging of Dopamine in Healthy Study Participants

NCT00062946

COMPLETED

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning

NCT00062517

COMPLETED

The Effects of Estrogen Withdrawal on Mood Symptoms in Women

NCT00060736

COMPLETED

Brain Regulation of Emotions in People With Depression and Anhedonia

NCT00059579

TERMINATED Phase 2

Clinical Trial of Estrogen for Postpartum Depression

NCT00059228

COMPLETED

Brain Imaging of Serotonin Transporters in the Brain

NCT00059046

COMPLETED Phase 1

Effects of Modafinil on Brain Function in Patients With Schizophrenia

NCT00057707

TERMINATED

Screening Evaluation for Women With Postpartum Depression

NCT00056901

COMPLETED NA

Expectation of Unpleasant Events in Anxiety Disorders

NCT00055224

TERMINATED Phase 2

Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studies

NCT00055575

COMPLETED

Effect of Hydrocortisone on the Brain

NCT00055003

COMPLETED Phase 2

Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia

NCT00061789

TERMINATED Phase 2

Riluzole to Treat Depression in Bipolar Disorder

NCT00054704

COMPLETED

Brain Imaging in Depression

NCT00050700

COMPLETED Phase 4

Evaluation of Stress Disorders

NCT00050804

COMPLETED NA

Brain Imaging Changes in Fear and Anxiety

NCT00047853

TERMINATED

Screening for Childhood-Onset Psychotic Disorders

NCT00049738

COMPLETED

MRI Study of Brain Activity and Risk for Depression in Adolescents

NCT00047944

COMPLETED Phase 4

The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease

NCT00046358

COMPLETED

Brain Receptor Function in Post-Traumatic Stress Disorder

NCT00046553

COMPLETED

Characterization of Childhood-Onset Obsessive-Compulsive Disorder

NCT00044239

COMPLETED

Psychopharmacology of Fear-Potentiated Startle in Humans

NCT00044096

COMPLETED Phase 2

Clinical Trial of Mifepristone for Bipolar Depression

NCT00043654

TERMINATED Phase 2

Clinical Trial of Tolcapone for Cognition in Schizophrenia

NCT00044083

COMPLETED Phase 2

Examination of a Soy-Based Supplement for Major Depression

NCT00042380

COMPLETED

Effects of Yohimbine and Naltrexone on Sexual Function

NCT00042536

COMPLETED Phase 3

Clinical Trial of Memantine for Major Depression

NCT00040261

COMPLETED Phase 4

Ethnic Variations in Antidepressant Response

NCT00047671

COMPLETED

Brain Imaging in Alzheimer's Disease

NCT00039702

COMPLETED

Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder

NCT00039715

COMPLETED Phase 3

Clozapine vs. Placebo in Treatment-Refractory Bipolar Disorder in Children and Adolescents

NCT00036582

COMPLETED

Serotonin Function During Depression

NCT00033787

COMPLETED

Effect of D-cycloserine on Extinction of Fear Conditioning

NCT00352586

COMPLETED Phase 2

Clinical Trial of Felbamate for Treatment-Resistant Bipolar Depression

NCT00034229

COMPLETED

PET Scanning in Parkinson s Disease

NCT00024622

COMPLETED

Effects of Stress Hormones on Emotion and Cognition

NCT00032838

COMPLETED Phase 4

Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression

NCT00031317

COMPLETED Phase 4

Raloxifene and Rimostil for Perimenopause-Related Depression

NCT00030147

COMPLETED

Reward-Related Processes and Brain Function

NCT00029588

COMPLETED

Cortical Excitability in Obsessive-Compulsive and Related Disorders

NCT00029068

COMPLETED Phase 2

Clozapine for Treatment-Resistant Mania

NCT00029458

COMPLETED

Brain Receptors in Sympathetic Nervous System Regulation

NCT00029627

COMPLETED

The Treatment of Children and Adolescents With Treatment-Resistant Depression

NCT00029640

COMPLETED

Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder

NCT00029120

COMPLETED

Ventilatory Physiology in Children at Risk for Anxiety

NCT00101777

COMPLETED Phase 2

Examination of Tamoxifen in Acute Mania in Patients With Bipolar I Disorder

NCT00026585

COMPLETED

Behavior in Children With Attention Deficit Hyperactivity Disorder and in Healthy Volunteers

NCT00026546

COMPLETED Phase 2

Riluzole to Treat Major Depression

NCT00026052

COMPLETED

Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder

NCT00025974

COMPLETED

Brain Function in Mentally Ill Adolescents

NCT00025857

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Phase Distribution

PhaseTrial count
Phase 1 61
Phase 2 45
Phase 3 8
Phase 4 21

What the Pipeline for National Institute of Mental Health (NIMH) Shows

According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.

The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.