National Institute of Mental Health (NIMH)
National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.
Trial Pipeline
343 total, page 5 of 7
PET Imaging of Dopamine in Healthy Study Participants
NCT00062946
Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning
NCT00062517
The Effects of Estrogen Withdrawal on Mood Symptoms in Women
NCT00060736
Brain Regulation of Emotions in People With Depression and Anhedonia
NCT00059579
Clinical Trial of Estrogen for Postpartum Depression
NCT00059228
Brain Imaging of Serotonin Transporters in the Brain
NCT00059046
Effects of Modafinil on Brain Function in Patients With Schizophrenia
NCT00057707
Screening Evaluation for Women With Postpartum Depression
NCT00056901
Expectation of Unpleasant Events in Anxiety Disorders
NCT00055224
Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studies
NCT00055575
Effect of Hydrocortisone on the Brain
NCT00055003
Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia
NCT00061789
Riluzole to Treat Depression in Bipolar Disorder
NCT00054704
Brain Imaging in Depression
NCT00050700
Evaluation of Stress Disorders
NCT00050804
Brain Imaging Changes in Fear and Anxiety
NCT00047853
Screening for Childhood-Onset Psychotic Disorders
NCT00049738
MRI Study of Brain Activity and Risk for Depression in Adolescents
NCT00047944
The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease
NCT00046358
Brain Receptor Function in Post-Traumatic Stress Disorder
NCT00046553
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
NCT00044239
Psychopharmacology of Fear-Potentiated Startle in Humans
NCT00044096
Clinical Trial of Mifepristone for Bipolar Depression
NCT00043654
Clinical Trial of Tolcapone for Cognition in Schizophrenia
NCT00044083
Examination of a Soy-Based Supplement for Major Depression
NCT00042380
Effects of Yohimbine and Naltrexone on Sexual Function
NCT00042536
Clinical Trial of Memantine for Major Depression
NCT00040261
Ethnic Variations in Antidepressant Response
NCT00047671
Brain Imaging in Alzheimer's Disease
NCT00039702
Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder
NCT00039715
Clozapine vs. Placebo in Treatment-Refractory Bipolar Disorder in Children and Adolescents
NCT00036582
Serotonin Function During Depression
NCT00033787
Effect of D-cycloserine on Extinction of Fear Conditioning
NCT00352586
Clinical Trial of Felbamate for Treatment-Resistant Bipolar Depression
NCT00034229
PET Scanning in Parkinson s Disease
NCT00024622
Effects of Stress Hormones on Emotion and Cognition
NCT00032838
Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression
NCT00031317
Raloxifene and Rimostil for Perimenopause-Related Depression
NCT00030147
Reward-Related Processes and Brain Function
NCT00029588
Cortical Excitability in Obsessive-Compulsive and Related Disorders
NCT00029068
Clozapine for Treatment-Resistant Mania
NCT00029458
Brain Receptors in Sympathetic Nervous System Regulation
NCT00029627
The Treatment of Children and Adolescents With Treatment-Resistant Depression
NCT00029640
Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder
NCT00029120
Ventilatory Physiology in Children at Risk for Anxiety
NCT00101777
Examination of Tamoxifen in Acute Mania in Patients With Bipolar I Disorder
NCT00026585
Behavior in Children With Attention Deficit Hyperactivity Disorder and in Healthy Volunteers
NCT00026546
Riluzole to Treat Major Depression
NCT00026052
Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder
NCT00025974
Brain Function in Mentally Ill Adolescents
NCT00025857
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 61 |
| Phase 2 | 45 |
| Phase 3 | 8 |
| Phase 4 | 21 |
Therapeutic Areas
What the Pipeline for National Institute of Mental Health (NIMH) Shows
According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.
The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.