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NCT00055224 · ClinicalTrials.gov registry record · NA

Expectation of Unpleasant Events in Anxiety Disorders

A NA study, sponsored by National Institute of Mental Health (NIMH).

Completed
Registry status
NA
Development phase
921
Enrollment target

NCT00055224 is a NA study that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 921 participants.

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The verdict

NCT00055224, a NA study, has completed, sponsored by National Institute of Mental Health (NIMH).

COMPLETED
Registry status
NA
Development phase
921 participants
Enrollment target

Study Summary

Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate. This study will examine changes in the body and brain that occur during unpleasant learning experiences in healthy volunteers with high, moderate, and low levels of anxiety. A high degree of generalized anxiety is a component of many anxiety disorders and is regarded as a marker of vulnerability for these disorders. People with anxiety disorders and individuals with high degrees of anxiety have inappropriate expectations of unpleasant events. This study will investigate the development of expecting unpleasant events in healthy volunteers with varying degrees of anxiety using aversive conditioning models. A later phase of the study will enroll participants with anxiety disorders and compare their responses to those of healthy volunteers. Patients who meet criteria for an anxiety disorder, and healthy volunteers who have no history of psychiatric or major medical illness will be enrolled in this study. Volunteers will come to the NIH Clinical Center three times for outpatient testing....

Interventions

  • DEVICE Threat of shock

Trial Details

FieldValue
Enrollment Target 921 participants
Start Date 2003-03-24
Est. Completion 2022-07-28
Phase NA

What the Registry Record Tells You About NCT00055224

The ClinicalTrials.gov registry entry for NCT00055224 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 921 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Threat of shock is the first listed.

NCT00055224 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00055224 about?

NCT00055224 is a clinical study titled "Expectation of Unpleasant Events in Anxiety Disorders". Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate. This study will examine changes in the body and brain that occur during unpleasant learning experiences in healthy volunteers with high, moderate,...

What is the current status of trial NCT00055224?

This trial is currently completed. It is a NA study. The enrollment target is 921 participants. The study started on 2003-03-24. Estimated completion is 2022-07-28.

What interventions are being tested in trial NCT00055224?

The interventions under investigation include: Threat of shock (DEVICE).

Who is sponsoring clinical trial NCT00055224?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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