National Institute of Mental Health (NIMH)

343 total trials 42 currently recruiting 256 completed

National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.

Trial Pipeline

343 total, page 6 of 7

COMPLETED

Fear Conditioning Using Computer-Generated Virtual Reality

NCT00025844

COMPLETED

Examination of Brain Serotonin Receptors in Patients With Mood Disorders

NCT00026832

COMPLETED Phase 4

Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder

NCT00025740

COMPLETED NA

Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders

NCT00025779

COMPLETED Phase 2

Clinical Trial of Pramipexole in Bipolar Depression

NCT00025792

COMPLETED Phase 4

Sequenced Treatment Alternatives to Relieve Depression (STAR*D)

NCT00021528

COMPLETED

Adolescence, Puberty, and Emotion Regulation

NCT00016731

COMPLETED Phase 2

Clinical Trial of Propranolol for Seasonal Affective Disorder

NCT00016666

COMPLETED Phase 2

Pilot Study of Levetiracetam (Keppra® (Registered Trademark)) for Bipolar Illness

NCT00015769

COMPLETED Phase 1

Effects of an Anti-Inflammatory Drug in Alzheimer's Disease

NCT00013650

COMPLETED NA

CATIE-Alzheimer's Disease Trial

NCT00015548

COMPLETED

Brain Imaging in Children With AD/HD

NCT00008892

COMPLETED NA

Effects of Arousal and Stress in Anxiety

NCT00026559

COMPLETED Phase 4

CATIE- Schizophrenia Trial

NCT00014001

COMPLETED NA

Treatment of Youth With ADHD and Anxiety

NCT00012584

COMPLETED

Use of Transcranial Magnetic Stimulation (TMS) and Magnetic Resonance Imaging (MRI) to Study Visual Attention

NCT00006285

COMPLETED

Child & Adolescent Bipolar Disorder Brain Imaging and Treatment Study

NCT00006177

COMPLETED Phase 4

Bone Loss in Premenopausal Women With Depression

NCT00006180

COMPLETED Phase 2

Glycine to Treat Psychotic Disorders in Children

NCT00005658

COMPLETED

Combined Hormone Replacement in Menstrually-Related Mood Disorders

NCT00005011

COMPLETED

Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers

NCT00004571

COMPLETED

Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions

NCT00004550

COMPLETED

The Effect of Acetylcholine on Memory and Attention

NCT00001977

COMPLETED

Heart Disease Risk Factors in Major Depression

NCT00001969

COMPLETED Phase 2

Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial

NCT00001146

COMPLETED

Electrophysiology and Blood Flow in Patients With Schizophrenia and Their Siblings

NCT00001921

COMPLETED

Neuroimaging of St. John's Wort-Induced Changes of Serotonin Metabolism in Normal Subjects

NCT00001919

COMPLETED

Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia

NCT00001920

COMPLETED

L-5-HTP-Related EMS

NCT00001918

COMPLETED

Brain Imaging in Elderly People and Individuals With Alzheimer's Disease

NCT00001917

COMPLETED

Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression

NCT00001916

COMPLETED Phase 3

Behavior Therapy for Children and Adolescents With Obsessive-Compulsive Disorder (OCD)

NCT00000386

COMPLETED NA

Treatment of Major Depression With St. John's Wort (Hypericum)

NCT00005013

COMPLETED

The Impact of Familiarity and Emotional Attachment on the Visual Processing of Faces

NCT00001913

COMPLETED

Evaluation of Patients With Rapid Cycling Bipolar Disorder (RCBD)

NCT00001772

COMPLETED Phase 3

Treatment for Adolescents With Depression Study (TADS)

NCT00006286

COMPLETED NA

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

NCT00012558

COMPLETED

I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers

NCT00001771

COMPLETED Phase 3

Self-Management Therapy for Youth With Schizophrenia

NCT00000387

COMPLETED NA

Study of Fluoxetine in Patients With Depersonalization Disorder

NCT00004446

COMPLETED NA

Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

NCT00004451

COMPLETED

Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)

NCT00001770

COMPLETED Phase 3

Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)

NCT00001768

COMPLETED Phase 3

Treatment of Autism in Children and Adolescents

NCT00005014

COMPLETED Phase 4

Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections

NCT00001658

COMPLETED

Consequences of Conjugal Bereavement in Adults

NCT00001659

COMPLETED Phase 4

Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic Disorders

NCT00001656

COMPLETED

Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Chronic Posttraumatic Stress Disorder (PTSD)

NCT00001657

COMPLETED

The Role of Emotion in the Development of Psychopathology

NCT00001654

COMPLETED Phase 4

Continuation Electroconvulsive Therapy Vs Medication to Prevent Relapses in Patients With Major Depressive Disorder

NCT00000375

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Phase Distribution

PhaseTrial count
Phase 1 61
Phase 2 45
Phase 3 8
Phase 4 21

What the Pipeline for National Institute of Mental Health (NIMH) Shows

According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.

The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.