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NCT00059579 · ClinicalTrials.gov registry record
Brain Regulation of Emotions in People With Depression and Anhedonia
A clinical trial of Major Depressive Disorder, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 163
- Enrollment target
- 1
- Study location
NCT00059579: Completed study of Major Depressive Disorder, sponsored by National Institute of Mental Health (NIMH).
NCT00059579 is a study of Major Depressive Disorder that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 163 participants, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00059579, a study of Major Depressive Disorder, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 163 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will use magnetic resonance imaging (MRI) to examine how the brain regulates emotions in healthy people and in patients who have major depression and anhedonia (loss of feeling of pleasure in things that normally give pleasure). Healthy normal volunteers and patients between 18 and 50 years of age with major depression, with or without significant anhedonia, are eligible for this study. Candidates will be screened with a psychiatric interview, a physical examination that will include blood and urine samples, and an electrocardiogram, and a questionnaire about their emotions. Participants will perform a monetary reward task while lying in an MRI scanner. The task is similar to playing a computer video game with the possibility of winning cash. The amount of cash is largely dependent on the subject's performance. The accumulated amount of cash earned in a session will fluctuate depending on the subject's continuing performance level. That is, during a single session, a subject could lose money earned early in the session if his or her performance later in the session is not as good as earlier. MRI pictures will be taken during performance of the task. MRI uses a magnetic field and radio waves to produce images of body tissues and organs. The patient lies on a table that is moved into the scanner (a narrow cylinder) and wears earplugs to muffle loud knocking and thumping sounds that occur during the scanning process. The procedure will last about 1 to 1-1/2 hours.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 163 participants |
| Start Date | 2003-04-24 |
| Est. Completion | 2010-11-12 |
What the finished NCT00059579 record still lists
NCT00059579 is an observational study that tracks outcomes without assigning an intervention. The registered 163 participants enrollment target is mid-sized for trials with a published cap, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (57% lower).
The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 0 interventions.
NCT00059579 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00059579 about?
NCT00059579 is a clinical study titled "Brain Regulation of Emotions in People With Depression and Anhedonia". This study will use magnetic resonance imaging (MRI) to examine how the brain regulates emotions in healthy people and in patients who have major depression and anhedonia (loss of feeling of pleasure in things that normally give pleasure). Healthy normal volunteers and patients between 18 and 50 ye...
What is the current status of trial NCT00059579?
This trial is currently completed. The enrollment target is 163 participants. The study started on 2003-04-24. Estimated completion is 2010-11-12.
What conditions does trial NCT00059579 study?
This clinical trial studies the following conditions: Major Depressive Disorder.
Who is sponsoring clinical trial NCT00059579?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00059579 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depressive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00059579's enrollment target sits among peer trials
163 94th of 282 higher than 189 of 282 other Major Depressive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depressive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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