Ohio State University Comprehensive Cancer Center
Trial Pipeline
Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
NCT07144826
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
NCT06424522
Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer
NCT07407647
Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer
NCT07474519
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
NCT07386444
Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia
NCT07166419
Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study
NCT07215988
Strategies for Optimizing a Mailed FIT Program in Appalachia
NCT07173985
Living Well With Advanced Breast Cancer
NCT07227038
A Patient Navigation Intervention for the Improvement of Risk Management Among Women at High Risk of Breast Cancer
NCT06950008
A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer
NCT07124611
Spine Oncology Registry
NCT07225491
Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer
NCT06391099
Examining Heavy Metal Exposure and Respiratory Health in Young Adult Electronic Cigarette Users
NCT07215065
Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences
NCT07111234
Studying the Effects of Nicotine Concentration and Flavor on Alcohol Use in Young Adults
NCT07095140
The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients
NCT07341503
Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia
NCT06763536
Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
NCT06964737
Studying the Health Perceptions and Social Behaviors of Graduate Students at the Ohio State University for the Development of Effective Oral Nicotine Pouch Addictive Risk Communication
NCT07346092
Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery
NCT06949943
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
NCT06749210
Addiction Potential of Very Low Nicotine Filtered Little Cigars
NCT06630728
Informing Oral Nicotine Pouch Regulations to Promote Public Health
NCT06315881
Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff
NCT06249984
Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
NCT05941858
Food for Thought - A Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer
NCT06582615
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women
NCT06635005
68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas
NCT06500065
Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer
NCT06330805
Manipulating E-Cigarette Nicotine to Promote Public Health
NCT06448351
Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study
NCT06208202
Designing a Dyad-Based MHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
NCT06746012
A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
NCT06260683
Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer
NCT06323460
The Ohio State University (OSU) SCREEN Community Program
NCT06666192
Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior
NCT06192316
Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic Cancer
NCT06396598
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
NCT06223659
Inspiratory Muscle Training in Obese Breast Cancer Survivors
NCT05193149
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
NCT05984888
Impact of Dietary Inflammatory Potential on Breast Cancer Risk
NCT05178498
Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial
NCT06314672
Weighted Blanket Use to Reduce Anxiety in Oncology Patients
NCT06089408
Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
NCT05961982
Head and Neck Cancer Patient Symptom and Oncologic Outcomes
NCT05243069
Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)
NCT05178472
Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
NCT05417308
Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cancer
NCT05677802
Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia
NCT05336812
Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer
NCT05415709
Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer
NCT04754321
Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer
NCT04780568
Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer
NCT05136846
Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction
NCT04049539
Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise
NCT04427566
Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions
NCT03492151
Smoking Cessation Intervention Development for Homeless Youth
NCT06754215
Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer
NCT03199651
An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry
NCT02677961
Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
NCT02090530
A Storage Facility for Tissues Obtained From Patients With Malignant Melanoma
NCT04567706
Hairy Cell Leukemia Patient Data Registry
NCT02560883
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
NCT01408225
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
NCT04022616
Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck
NCT01473784
Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers
NCT06644664
Transcutaneous Sensors for the Detection of Cancer-Related Lymphedema, Project Limb Rescue Study
NCT06305884
Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial
NCT06445192
Respiratory Effects of E-Cigarettes in Obese Youth
NCT05869318
Bioavailability and Pharmacodynamics of EPA and DHA From Fortified Soymilk and Capsules
NCT05802797
Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases
NCT05503251
Genetic Counseling Patient Preference Intervention Versus Conventional Genetic Counseling for Women at Elevated Risk for Breast Cancer
NCT05325151
A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer
NCT05215769
Impact of E-cigarette Use on the Body
NCT04972513
Web-Based Symptom Monitoring and Self-Management Portal (YES) for Adolescent and Young Adult Breast Cancer Survivors
NCT04906200
Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study
NCT05972577
Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
NCT05717998
Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy
NCT04713618
Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities
NCT04340531
Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)
NCT04537312
I Vaccinate: Testing Multi-Level Interventions to Improve HPV Vaccination
NCT04452526
A Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint Inhibitors
NCT06630429
Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer
NCT04116970
Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia
NCT04466683
High Dose Vitamin A in Preventing Gastrointestinal GVHD in Participants Undergoing Donor Stem Cell Transplant
NCT03719092
Venetoclax and Ibrutinib in Treating in Participants With Chronic Lymphocytic Leukemia and Ibrutinib Resistance Mutations
NCT03513562
Papaverine and Stereotactic Body Radiotherapy (SBRT) for Non Small Cell Lung Cancer (NSCLC) or Lung Metastases
NCT03824327
Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer
NCT03786354
Nanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large B-Cell Lymphoma
NCT03656835
Risk of Chemotherapy Toxicity in Older Patients With Blood Cancer or Non-small Cell Lung Cancer
NCT05106374
Metabolism and Absorption of Anthocyanins From Extract and Whole Blueberry Powder Confections in Healthy Adults
NCT04329962
Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction
NCT02927912
Ibrutinib and Nivolumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma
NCT02940301
Food Frequency Questionnaires in Estimating Food Nutrient Intake in Healthy Young Adults
NCT02610023
Cardiac MRI in Measuring the Impact of Anti-androgen Treatment on Cardiac Function in Patients With Prostate Cancer
NCT02722525
Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers
NCT01961869
Aborption and Metabolism of Lyophilized Black Raspberry Food Products in Men With Prostate Cancer Undergoing Surgery
NCT01823562
Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy
NCT02259218
The Parents in Appalachia Receive Education Needed for Teen Project
NCT01901770
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 54 |
| Phase 2 | 50 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for Ohio State University Comprehensive Cancer Center Shows
According to the ClinicalTrials.gov registry, Ohio State University Comprehensive Cancer Center is linked to 291 US clinical trials across every stage of research activity. Of those, 211 studies are currently recruiting — about 73% of the sponsor's indexed portfolio — and 44 are already marked complete, representing roughly 15% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Ohio State University Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 104 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Ohio State University Comprehensive Cancer Center is Anatomic Stage II Breast Cancer AJCC v8 with 10 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.