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NCT00057707 · ClinicalTrials.gov registry record · Phase 1
Effects of Modafinil on Brain Function in Patients With Schizophrenia
A Phase 1 study, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- Phase 1
- Development phase
- 176
- Enrollment target
NCT00057707: Completed Phase 1 study, sponsored by National Institute of Mental Health (NIMH).
NCT00057707 is a Phase 1 study that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 176 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (193% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00057707, a Phase 1 study, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 176 participants
- Enrollment target
Study Summary
This study will evaluate whether modafinil improves cognition in patients with schizophrenia and healthy volunteers. Modafinil is a drug that has been FDA approved for day-time sleepiness and allegedly increase the amount of the neurotransmitter dopamine in the frontal cortex of the brain ...
Interventions
- DRUG Modafinil
- PROCEDURE Functional MRI
- PROCEDURE Neuropsychological Testing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 176 participants |
| Start Date | 2003-03-26 |
| Est. Completion | 2017-06-16 |
| Phase | Phase 1 |
What the finished NCT00057707 record still lists
NCT00057707 is an interventional study that assigns participants to a tested intervention. The registered 176 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (193% higher).
The record links to 0 conditions, and to 3 interventions - of which Modafinil is the first listed.
NCT00057707 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00057707 about?
NCT00057707 is a clinical study titled "Effects of Modafinil on Brain Function in Patients With Schizophrenia". This study will evaluate whether modafinil improves cognition in patients with schizophrenia and healthy volunteers. Modafinil is a drug that has been FDA approved for day-time sleepiness and allegedly increase the amount of the neurotransmitter dopamine in the frontal cortex of the brain ...
What is the current status of trial NCT00057707?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 176 participants. The study started on 2003-03-26. Estimated completion is 2017-06-16.
What interventions are being tested in trial NCT00057707?
The interventions under investigation include: Modafinil (DRUG), Functional MRI (PROCEDURE), Neuropsychological Testing (PROCEDURE).
Who is sponsoring clinical trial NCT00057707?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00057707's enrollment target sits among peer trials
176 316th of 2000 higher than 1,682 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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