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NCT00032838 · ClinicalTrials.gov registry record
Effects of Stress Hormones on Emotion and Cognition
A clinical trial of Healthy, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 170
- Enrollment target
- 1
- Study location
NCT00032838: Completed study of Healthy, sponsored by National Institute of Mental Health (NIMH).
NCT00032838 is a study of Healthy that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 170 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00032838, a study of Healthy, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 170 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine how hormonal changes that occur during stressful situations affect thought and emotions. Results from this study may lead to treatments that can alleviate the psychological effects of trauma. Levels of cortisol and norepinephrine increase in response to stress; these hormones also influence thought processes. This study will give hydrocortisone and/or yohimbine (a stimulator of central norepinephrine) to healthy adults in order to model the stress response and to better understand the way people process information during traumatic events. This study comprises two experiments in which the stress response is pharmacologically modeled. Participants in the study will have two study visits. During Visit 1, participants will undergo a psychiatric assessment, complete neuropsychological tasks, and have their IQ measured. During Visit 2, participants will be given hydrocortisone and/or yohimbine. Blood will be collected before and during this. Participants will then perform two experiments. In one experiment, participants will hear a story with emotional and non-emotional segments; in a second experiment, participants will view both emotional and non-emotional stimuli.
Conditions Studied
Interventions
- DRUG Yohimbine
Study Locations (1)
Maryland
- National Institute of Mental Health (NIMH) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2002-03 |
| Est. Completion | 2006-01 |
What the finished NCT00032838 record still lists
NCT00032838 is an observational study that tracks outcomes without assigning an intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Yohimbine is the first listed.
NCT00032838 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00032838 about?
NCT00032838 is a clinical study titled "Effects of Stress Hormones on Emotion and Cognition". The purpose of this study is to examine how hormonal changes that occur during stressful situations affect thought and emotions. Results from this study may lead to treatments that can alleviate the psychological effects of trauma. Levels of cortisol and norepinephrine increase in response to stres...
What is the current status of trial NCT00032838?
This trial is currently completed. The enrollment target is 170 participants. The study started on 2002-03. Estimated completion is 2006-01.
What conditions does trial NCT00032838 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT00032838?
The interventions under investigation include: Yohimbine (DRUG).
Who is sponsoring clinical trial NCT00032838?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00032838 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00032838's enrollment target sits among peer trials
170 141st of 1090 higher than 949 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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