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Healthy Volunteer: early-phase trial registry
49 of 113 indexed Healthy Volunteer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #113 of 28,707 conditions by registered trial count.
113 US clinical trials · 49 currently recruiting · #113 of 28,707 conditions by registered trial count
Healthy Volunteer: 113 US clinical trials tracked, 49 recruiting.
Healthy Volunteer is the subject of 113 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 86 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 15 of these trials.
Enrollment posture brief
Registry condition healthy-volunteer
OPEN 49 | RECR 43% | LATE 0 | EARLY 86 | RANK #113 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Bronchopulmonary Dysplasia (43% recruiting · 30 trials)
Healthy Volunteer lists 49 open slots (43% of 113 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Volunteer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Healthy Volunteer is recruiting above its size-band peers.
49 of 113 indexed trials (43.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Healthy Volunteer trials is spread across many organizations.
AbbVie accounts for 15 of 113 trials (13.3%). 56 distinct sponsors appear on at least one study for this condition label.
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Most Healthy Volunteer trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 113 trials that report a genuine target (sentinel values excluded). 80 of those (70.8%) plan for fewer than 100 participants.
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Healthy Volunteer research is mostly interventional.
95 interventional and 18 observational studies make up this index (84.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
113 total, page 1 of 3
Studies of Blood Flow to the Brain During Thought
National Institute of Mental Health (NIMH)
NCT00001360
Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies
National Institute of Mental Health (NIMH)
NCT03304665
Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05078905
Characterization of Diseases With Salivary Gland Involvement
National Institute of Dental and Craniofacial Research (NIDCR)
NCT02327884
Study of New Magnetic Resonance Imaging Methods of the Brain
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00004577
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
National Institute of Dental and Craniofacial Research (NIDCR)
NCT01568697
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy
National Cancer Institute (NCI)
NCT02821806
Normal Values in Hearing and Balance Testing
National Institute on Deafness and Other Communication Disorders (NIDCD)
NCT01629108
Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03878121
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle
National Institute of Mental Health (NIMH)
NCT01266577
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
Akiva Mintz
NCT07012993
Ultralow Dose PET Imaging of 18F-FDG Uptake
Akiva Mintz
NCT06956391
Ultralow Dose PET Imaging for 18F-NaF Uptake
Akiva Mintz
NCT07284563
Ultralow Dose PET Imaging for PSMA Expression
Akiva Mintz
NCT06904313
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
NCT06624137
Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial
National Institute on Aging (NIA)
NCT06274749
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
National Institute of Mental Health (NIMH)
NCT03065335
Collection of Data and Samples From Healthy Donors for Use in Translational Research
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00090662
Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05652478
A Study to Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult Participants
Biogen
NCT07225517
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
Washington University School of Medicine
NCT04354064
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
University of Pennsylvania
NCT03721822
A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants
AbbVie
NCT06673238
A Study to Evaluate How the Study Drug Moves Through the Body, Adverse Events, and How the Body Tolerates ABBV-547 Injections
AbbVie
NCT07232004
Phosphatidylethanol and Other Ethanol Consumption Markers
The University of Texas Health Science Center at San Antonio
NCT06747364
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
University of Alabama at Birmingham
NCT06989320
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06223555
A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old
Biogen
NCT07133828
A First-in-Human Single and Multiple Ascending Dose Study of MT-201
Mirador Therapeutics
NCT07219368
Study About Whether Atirmociclib/PF-07220060 Proportionally Increases Exposure as Dose Increases in Healthy Participants
Pfizer
NCT07215078
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
Suninflam
NCT07051629
A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55
Biogen
NCT07297199
A Study to Compare Blood Levels of Different Dosage Formulations of the Study Medicine That Is a CGRP Receptor Antagonist in Healthy Adults
Pfizer
NCT07261371
A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults
Astellas Pharma Global Development
NCT07395024
Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT06819189
A Study to Assess the Adverse Events and How Oral ABBV-1042 Moves Through the Body of Healthy Adult Participants
AbbVie
NCT07222709
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
Basilea Pharmaceutica
NCT06733675
Randomized, Open-label, Safety Study of Subcutaneous and Intramuscular Injections of Niagen® Plus
ChromaDex
NCT07251608
A Study to Assess How the Body Absorbs ABBV-8736 Subcutaneous Injections Relative to Intravenous Injections in Adult Healthy Volunteers
AbbVie
NCT07413133
Healthy Volunteer Study
InventisBio Co.
NCT07270783
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants
AbbVie
NCT07219030
Avocado and Postprandial Responses
University of Vermont Medical Center
NCT06818032
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Vanderbilt University Medical Center
NCT06609356
Power Nap With TES-TI
University of Wisconsin, Madison
NCT07090135
Evaluation of Single Dosing With Two F/TAF Tablets Among Healthy Volunteers
Johns Hopkins University
NCT07349758
Neuroinflammation Imaging in AD
University of Pennsylvania
NCT04274998
A Study of ABBV-295 Subcutaneous Injections to Assess Pharmacokinetics and Adverse Events in Healthy Adult Women Participants With Overweight or Obesity Taking Oral Contraceptives
AbbVie
NCT07414784
Relative Bioavailability of NX-5948 Tablets vs Capsules and the Effect of Covariates on the PK of NX-5948 Tablets
Nurix Therapeutics
NCT06717269
Psychedelic Virtual Reality
Yale University
NCT06581263
A Study to Find Out How Litifilimab is Processed in the Body in Healthy Participants When Given Under the Skin in 3 Different Ways
Biogen
NCT06741657
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 80 |
| Phase 2 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Volunteer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Volunteer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Volunteer page
113 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 49 Healthy Volunteer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- AbbVie sponsors the most Healthy Volunteer trials on record, review their full trial history before evaluating a specific study. See AbbVie's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Volunteer condition card totals 113 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.