University of Iowa

156 total trials 110 currently recruiting 33 completed

Trial Pipeline

RECRUITING

Genetic Risk Factor for Heat Stroke

NCT06847256

RECRUITING NA

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

NCT07244809

RECRUITING NA

Robotic-Assisted Versus Manual Electrode Array Insertion

NCT06951594

RECRUITING NA

Effect of Custom Dynamic Orthoses on Forefoot Loading

NCT06710119

RECRUITING Phase 2

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607

RECRUITING NA

E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

NCT07032350

RECRUITING

PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department

NCT07086560

RECRUITING

Aquagenic Wrinkling Prediction

NCT06831110

RECRUITING NA

Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial

NCT06840093

RECRUITING Phase 2

IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

NCT06559969

RECRUITING NA

Cognitive Control to Boost Physical Activity Adherence

NCT06338774

RECRUITING NA

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

NCT06127316

RECRUITING Early Phase 1

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

NCT06489249

RECRUITING Early Phase 1

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

NCT06499844

RECRUITING Phase 2

177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

NCT06395402

RECRUITING NA

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

NCT06127264

RECRUITING NA

Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

NCT06207318

RECRUITING Early Phase 1

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

NCT05461092

RECRUITING Phase 1

Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy

NCT05169060

RECRUITING

Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder

NCT06898671

RECRUITING Phase 2

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

NCT05239546

RECRUITING

COVID-19 Coagulopathy Extension Study

NCT05334615

RECRUITING

CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids

NCT04518722

RECRUITING

Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease

NCT05707663

RECRUITING NA

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

NCT04134754

RECRUITING NA

The Effects of AFO Heel Height and Stiffness on Gait

NCT04800484

RECRUITING

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

NCT01193088

ACTIVE NOT RECRUITING Phase 4

Pharmacokinetics of Transdermal Metronidazole

NCT05929794

ACTIVE NOT RECRUITING NA

Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

NCT04861571

ACTIVE NOT RECRUITING NA

Birth to Three - Cavity Free

NCT05756413

ACTIVE NOT RECRUITING NA

Activity and Cancer Survivorship Exercise Pilot

NCT07283029

ACTIVE NOT RECRUITING

Neuroendocrine Tumors - Patient Reported Outcomes

NCT05064150

ACTIVE NOT RECRUITING

Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

NCT05287204

ACTIVE NOT RECRUITING NA

Telerehabilitation After Shoulder Arthroplasty

NCT05499728

ACTIVE NOT RECRUITING Phase 1

Target Engagement of Terazosin in Healthy Adults

NCT04551040

ACTIVE NOT RECRUITING NA

Cerebellar TDCS for SRPCS Treatment

NCT04760899

ACTIVE NOT RECRUITING NA

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041

ACTIVE NOT RECRUITING NA

Cystoealstometer (Bladder Monitor Device)-Home Use

NCT05232253

ACTIVE NOT RECRUITING Early Phase 1

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

NCT04634227

ACTIVE NOT RECRUITING

Effects of Transitional Circulation in ELBW Infants

NCT02016599

COMPLETED NA

OPTIMAL in NH Residents With Dementia

NCT05255068

COMPLETED NA

Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics

NCT05209360

COMPLETED Phase 4

Cool vs Room-temperature Artificial Tears

NCT05832996

COMPLETED

Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge

NCT04709939

COMPLETED NA

Effects of Malleo-Lok Stiffness on Lower Limb Mechanics

NCT04806100

COMPLETED NA

INcreasing Steps in PREgnancy Study

NCT05455008

COMPLETED NA

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617

COMPLETED NA

Micropore Closure Kinetics at Various Body Sites

NCT03657277

COMPLETED NA

Precision-Based Approach to Matching Evidence-Based Interventions to Students With Externalizing Behaviors

NCT05752942

COMPLETED NA

Nitrate Supplementation and Muscle Blood Flow

NCT03459027

COMPLETED

Adductor Canal Block Ultrasound Anatomy in Volunteers

NCT03008564

COMPLETED Early Phase 1

Biodistribution/Reproducibility Ga-68 PSMA-HBED-CC

NCT02952469

COMPLETED Phase 1

TVEC and Preop Radiation for Sarcoma (4 ml Dose)

NCT02453191

COMPLETED Phase 1

ATRA, Celecoxib, and Itraconazole as Maintenance

NCT02401295

COMPLETED NA

A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants

NCT02668874

COMPLETED Phase 4

Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness

NCT02450383

COMPLETED NA

Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?

NCT02915874

COMPLETED

Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)

NCT02194010

COMPLETED

Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery

NCT02511457

COMPLETED

The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study

NCT01878071

COMPLETED NA

Nasotracheal Intubation Over a Bougie

NCT03003455

COMPLETED NA

Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants

NCT03156465

COMPLETED Phase 1

Aspirin Attenuates Inflammation in Human Cerebral Aneurysms

NCT01710072

COMPLETED NA

Ultrasound-image Guided Versus Doppler Guided Versus Palpation Technique for Arterial Cannulation in Adults

NCT01276171

COMPLETED NA

The Effectiveness of Smoking Cessation Guidelines in the Emergency Department

NCT00756704

COMPLETED Phase 2

F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients

NCT00721799

COMPLETED Phase 2

Zinc to Treat Tinnitus in the Elderly

NCT00683644

COMPLETED

Ultrasound Targeting for the Lumpectomy Cavity

NCT00583843

COMPLETED Phase 2

Atomoxetine and Huntington's Disease

NCT00368849

COMPLETED Phase 4

Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study

NCT00581893

COMPLETED NA

Improving Adherence to Blood Pressure Guidelines

NCT00201019

COMPLETED NA

Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment

NCT00565305

COMPLETED Phase 3

Magnetic Stimulation Therapy for Treating Vascular Depression

NCT00044798

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 34
Phase 3 1
Phase 4 4

What the Pipeline for University of Iowa Shows

According to the ClinicalTrials.gov registry, University of Iowa is linked to 156 US clinical trials across every stage of research activity. Of those, 110 studies are currently recruiting — about 71% of the sponsor's indexed portfolio — and 33 are already marked complete, representing roughly 21% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of Iowa reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 44 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of Iowa is Healthy with 6 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial