University of Iowa
Trial Pipeline
Genetic Risk Factor for Heat Stroke
NCT06847256
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
NCT07244809
Robotic-Assisted Versus Manual Electrode Array Insertion
NCT06951594
Effect of Custom Dynamic Orthoses on Forefoot Loading
NCT06710119
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
NCT06405607
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
NCT07032350
PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department
NCT07086560
Aquagenic Wrinkling Prediction
NCT06831110
Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial
NCT06840093
IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
NCT06559969
Cognitive Control to Boost Physical Activity Adherence
NCT06338774
The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses
NCT06127316
Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use
NCT06489249
Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation
NCT06499844
177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry
NCT06395402
Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff
NCT06127264
Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery
NCT06207318
Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
NCT05461092
Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
NCT05169060
Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder
NCT06898671
Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
NCT05239546
COVID-19 Coagulopathy Extension Study
NCT05334615
CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids
NCT04518722
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
NCT05707663
Carbon Dioxide (CO2) Chemosensitivity and SUDEP
NCT04134754
The Effects of AFO Heel Height and Stiffness on Gait
NCT04800484
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
NCT01193088
Pharmacokinetics of Transdermal Metronidazole
NCT05929794
Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD
NCT04861571
Birth to Three - Cavity Free
NCT05756413
Activity and Cancer Survivorship Exercise Pilot
NCT07283029
Neuroendocrine Tumors - Patient Reported Outcomes
NCT05064150
Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT
NCT05287204
Telerehabilitation After Shoulder Arthroplasty
NCT05499728
Target Engagement of Terazosin in Healthy Adults
NCT04551040
Cerebellar TDCS for SRPCS Treatment
NCT04760899
Casting vs Bracing for Idiopathic Early-Onset Scoliosis
NCT04500041
Cystoealstometer (Bladder Monitor Device)-Home Use
NCT05232253
Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)
NCT04634227
Effects of Transitional Circulation in ELBW Infants
NCT02016599
OPTIMAL in NH Residents With Dementia
NCT05255068
Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
NCT05209360
Cool vs Room-temperature Artificial Tears
NCT05832996
Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge
NCT04709939
Effects of Malleo-Lok Stiffness on Lower Limb Mechanics
NCT04806100
INcreasing Steps in PREgnancy Study
NCT05455008
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
NCT03659617
Micropore Closure Kinetics at Various Body Sites
NCT03657277
Precision-Based Approach to Matching Evidence-Based Interventions to Students With Externalizing Behaviors
NCT05752942
Nitrate Supplementation and Muscle Blood Flow
NCT03459027
Adductor Canal Block Ultrasound Anatomy in Volunteers
NCT03008564
Biodistribution/Reproducibility Ga-68 PSMA-HBED-CC
NCT02952469
TVEC and Preop Radiation for Sarcoma (4 ml Dose)
NCT02453191
ATRA, Celecoxib, and Itraconazole as Maintenance
NCT02401295
A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants
NCT02668874
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
NCT02450383
Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?
NCT02915874
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)
NCT02194010
Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery
NCT02511457
The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study
NCT01878071
Nasotracheal Intubation Over a Bougie
NCT03003455
Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants
NCT03156465
Aspirin Attenuates Inflammation in Human Cerebral Aneurysms
NCT01710072
Ultrasound-image Guided Versus Doppler Guided Versus Palpation Technique for Arterial Cannulation in Adults
NCT01276171
The Effectiveness of Smoking Cessation Guidelines in the Emergency Department
NCT00756704
F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients
NCT00721799
Zinc to Treat Tinnitus in the Elderly
NCT00683644
Ultrasound Targeting for the Lumpectomy Cavity
NCT00583843
Atomoxetine and Huntington's Disease
NCT00368849
Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study
NCT00581893
Improving Adherence to Blood Pressure Guidelines
NCT00201019
Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment
NCT00565305
Magnetic Stimulation Therapy for Treating Vascular Depression
NCT00044798
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 34 |
| Phase 3 | 1 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for University of Iowa Shows
According to the ClinicalTrials.gov registry, University of Iowa is linked to 156 US clinical trials across every stage of research activity. Of those, 110 studies are currently recruiting — about 71% of the sponsor's indexed portfolio — and 33 are already marked complete, representing roughly 21% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Iowa reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 44 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Iowa is Healthy with 6 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.