National Institute of Mental Health (NIMH)

343 total trials 42 currently recruiting 256 completed

National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.

Trial Pipeline

343 total, page 4 of 7

COMPLETED Phase 1

PET Whole Body Imaging Using a Peripheral Benzodiazepine Receptor Ligand [C-11]PBR28

NCT00407693

COMPLETED Phase 4

Minocycline to Treat Childhood Regressive Autism

NCT00409747

COMPLETED

PET Scanning of Adults With Attention Deficit Hyperactivity Disorder (ADHD)

NCT00397748

COMPLETED

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

NCT00362843

COMPLETED Phase 1

Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients

NCT00369798

TERMINATED Phase 2

The Antidepressant Efficacy of the Anticholinergic Scopolamine

NCT00369915

COMPLETED

Identifying the Role of Oxytocin and Vasopressin in the Functioning of Neurocognitive Systems Involved in Mood Disorders

NCT00325065

COMPLETED

Clinical and Immunological Investigations of Subtypes of Autism

NCT00298246

COMPLETED Phase 1

PET Imaging of Brain Peripheral Benzodiazepine Receptors

NCT00283920

COMPLETED Phase 1

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

NCT00263523

COMPLETED Phase 1

PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram

NCT00250172

COMPLETED Phase 2

Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia

NCT00128401

COMPLETED Phase 2

Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders

NCT00251303

COMPLETED

Dopamine Receptor Imaging in Mood Disorders

NCT00116077

COMPLETED

Attention and Visual Perception

NCT00111293

TERMINATED Phase 2

Org 24448 to Treat Major Depression

NCT00113022

COMPLETED

The Role of Norepinephrine in Emotional Processing

NCT00109642

COMPLETED

Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study

NCT00105274

COMPLETED

Effect of Transcranial Magnetic Stimulation on Memory

NCT00105118

COMPLETED

Brain Changes in Children and Adolescents With Behavioral Problems

NCT00104039

COMPLETED

Neurobiological Mechanisms in Panic Disorder

NCT00103987

COMPLETED

Role of Substance P in Post-Traumatic Stress Disorder

NCT00102102

COMPLETED Phase 4

Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication

NCT00375843

COMPLETED

Hormonal Causes of Menstrual-Related Mood Disorders

NCT00100360

COMPLETED

Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders

NCT00097175

COMPLETED

Relationship of Dopamine to Cognitive Function in Parkinson's Disease

NCT00094601

COMPLETED

Effect of Gabapentin on GABA Concentration and Emotional Processing

NCT00094510

COMPLETED

Investigating the Role of Serotonin in Emotional Processing Through the Use of Tryptophan Depletion

NCT00090831

COMPLETED

Psychological Mechanisms of Behavioral Dysregulation

NCT00352456

COMPLETED Phase 1

Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ

NCT00088738

COMPLETED Phase 1

Rapid Antidepressant Effects of Ketamine in Major Depression

NCT00088699

COMPLETED Phase 1

Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112

NCT00088517

TERMINATED Phase 2

Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives

NCT00089414

COMPLETED Phase 2

Lexapro and Pramipexole and to Treat Major Depression

NCT00086307

COMPLETED

Serotonin Transporters in Alcoholism

NCT00085865

COMPLETED

Family Study of Affective and Anxiety Spectrum Disorders

NCT00071786

COMPLETED

Genetic Causes of Panic Disorder

NCT00083265

COMPLETED

Serotonin Transporters in Obsessive-Compulsive-Related Disorders

NCT00082550

COMPLETED Phase 1

Use of [18F]FECNT in Positron Emission Tomography

NCT00083629

COMPLETED

Function of Catecholamines in the Brain During Depression

NCT00082030

COMPLETED Phase 1

Dutasteride to Treat Women With Menstrually Related Mood Disorders

NCT00082043

COMPLETED

Neurocardiac Control in Major Depression

NCT00084162

COMPLETED Phase 2

Rapid Antidepressant Effects of Yohimbine in Major Depression

NCT00078715

COMPLETED

FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression

NCT00075296

COMPLETED

The Psychobiology of Childhood Temperament

NCT00060775

COMPLETED

Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder

NCT00071123

COMPLETED

Psychobiological Mechanisms of Resilience to Trauma

NCT00069212

COMPLETED Phase 2

Propranolol for the Treatment of Acute Stress Disorder

NCT00069355

COMPLETED Phase 2

An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression

NCT00070694

COMPLETED

Brain Structure and Function Before and After Treatment for Post-Traumatic Stress Disorder

NCT00069225

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Phase Distribution

PhaseTrial count
Phase 1 61
Phase 2 45
Phase 3 8
Phase 4 21

What the Pipeline for National Institute of Mental Health (NIMH) Shows

According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.

The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.