National Institute of Mental Health (NIMH)
National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.
Trial Pipeline
343 total, page 4 of 7
PET Whole Body Imaging Using a Peripheral Benzodiazepine Receptor Ligand [C-11]PBR28
NCT00407693
Minocycline to Treat Childhood Regressive Autism
NCT00409747
PET Scanning of Adults With Attention Deficit Hyperactivity Disorder (ADHD)
NCT00397748
Protein Synthesis in the Brain of Patients With Fragile X Syndrome
NCT00362843
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients
NCT00369798
The Antidepressant Efficacy of the Anticholinergic Scopolamine
NCT00369915
Identifying the Role of Oxytocin and Vasopressin in the Functioning of Neurocognitive Systems Involved in Mood Disorders
NCT00325065
Clinical and Immunological Investigations of Subtypes of Autism
NCT00298246
PET Imaging of Brain Peripheral Benzodiazepine Receptors
NCT00283920
PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY
NCT00263523
PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram
NCT00250172
Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia
NCT00128401
Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders
NCT00251303
Dopamine Receptor Imaging in Mood Disorders
NCT00116077
Attention and Visual Perception
NCT00111293
Org 24448 to Treat Major Depression
NCT00113022
The Role of Norepinephrine in Emotional Processing
NCT00109642
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study
NCT00105274
Effect of Transcranial Magnetic Stimulation on Memory
NCT00105118
Brain Changes in Children and Adolescents With Behavioral Problems
NCT00104039
Neurobiological Mechanisms in Panic Disorder
NCT00103987
Role of Substance P in Post-Traumatic Stress Disorder
NCT00102102
Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication
NCT00375843
Hormonal Causes of Menstrual-Related Mood Disorders
NCT00100360
Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders
NCT00097175
Relationship of Dopamine to Cognitive Function in Parkinson's Disease
NCT00094601
Effect of Gabapentin on GABA Concentration and Emotional Processing
NCT00094510
Investigating the Role of Serotonin in Emotional Processing Through the Use of Tryptophan Depletion
NCT00090831
Psychological Mechanisms of Behavioral Dysregulation
NCT00352456
Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
NCT00088738
Rapid Antidepressant Effects of Ketamine in Major Depression
NCT00088699
Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112
NCT00088517
Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives
NCT00089414
Lexapro and Pramipexole and to Treat Major Depression
NCT00086307
Serotonin Transporters in Alcoholism
NCT00085865
Family Study of Affective and Anxiety Spectrum Disorders
NCT00071786
Genetic Causes of Panic Disorder
NCT00083265
Serotonin Transporters in Obsessive-Compulsive-Related Disorders
NCT00082550
Use of [18F]FECNT in Positron Emission Tomography
NCT00083629
Function of Catecholamines in the Brain During Depression
NCT00082030
Dutasteride to Treat Women With Menstrually Related Mood Disorders
NCT00082043
Neurocardiac Control in Major Depression
NCT00084162
Rapid Antidepressant Effects of Yohimbine in Major Depression
NCT00078715
FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression
NCT00075296
The Psychobiology of Childhood Temperament
NCT00060775
Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder
NCT00071123
Psychobiological Mechanisms of Resilience to Trauma
NCT00069212
Propranolol for the Treatment of Acute Stress Disorder
NCT00069355
An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
NCT00070694
Brain Structure and Function Before and After Treatment for Post-Traumatic Stress Disorder
NCT00069225
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 61 |
| Phase 2 | 45 |
| Phase 3 | 8 |
| Phase 4 | 21 |
Therapeutic Areas
What the Pipeline for National Institute of Mental Health (NIMH) Shows
According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.
The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.