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NCT00044239 · ClinicalTrials.gov registry record
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 49
- Enrollment target
NCT00044239: Completed study, sponsored by National Institute of Mental Health (NIMH).
NCT00044239 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 49 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00044239 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 49 participants
- Enrollment target
Study Summary
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time. A subset of children with OCD has a sudden onset and symptoms that fluctuate in severity over time. This study will also compare healthy children to those with OCD. This is an observational study; children who participate will not receive any new or experimental therapies. OCD affects nearly 1% of the pediatric population. The symptoms of this illness can interrupt development, causing significant psychological distress and producing life-long impairments in social, academic, and occupational functioning. A subgroup of pediatric OCD has been designated by the acronym PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections). This type of OCD is characterized by sudden symptom onset and a relapsing-remitting course of illness; exacerbation of symptoms occurs with scarlet fever or strep. throat infections. This study will identify factors that distinguish children with PANDAS OCD from children with non-PANDAS OCD, and will compare both groups to healthy children. Children with OCD and their parents are screened with interviews and a review of the child's medical records. Participants have an initial evaluation that includes a psychiatric, physical and neuromotor exam, neuropsychological testing, psychological interviews, and a blood test. Structural magnetic resonance imaging (MRS) scans of the brain are also obtained. The MRS scan does not use radiation. After the initial evaluation, children with OCD have follow-up visits every 6 weeks for 12 to 24 months. They are seen yearly for 8 years after the study. If they have a significant improvement or worsening of their symptoms, they are asked to make a maximum of two extra visits. Parents of OCD patients are called four times a year to discuss any changes in the child's condition between yearly
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2002-08-20 |
| Est. Completion | 2010-05-18 |
What the finished NCT00044239 record still lists
NCT00044239 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 49 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00044239 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00044239 about?
NCT00044239 is a clinical study titled "Characterization of Childhood-Onset Obsessive-Compulsive Disorder". The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time. A subset of children with OCD has a sudden onset and symptoms that fluctuate in severity over time. This study wil...
What is the current status of trial NCT00044239?
This trial is currently completed. The enrollment target is 49 participants. The study started on 2002-08-20. Estimated completion is 2010-05-18.
Who is sponsoring clinical trial NCT00044239?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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