Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obsessive - Compulsive Disorder: early-phase trial registry
30 of 86 indexed Obsessive - Compulsive Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #160 of 28,707 conditions by registered trial count.
86 US clinical trials · 30 currently recruiting · #160 of 28,707 conditions by registered trial count
Obsessive - Compulsive Disorder: 86 US clinical trials tracked, 30 recruiting.
Obsessive - Compulsive Disorder is the subject of 86 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.
Enrollment posture brief
Registry condition obsessive-compulsive-disorder
OPEN 30 | RECR 35% | LATE 10 | EARLY 19 | RANK #160 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Hemophilia A (35% recruiting · 43 trials)
Obsessive - Compulsive Disorder lists 30 open slots (35% of 86 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obsessive - Compulsive Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obsessive - Compulsive Disorder is recruiting below its size-band peers.
30 of 86 indexed trials (34.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obsessive - Compulsive Disorder trials is spread across many organizations.
Baylor College of Medicine accounts for 7 of 86 trials (8.1%). 45 distinct sponsors appear on at least one study for this condition label.
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Most Obsessive - Compulsive Disorder trials plan to enrol fewer than 100 people.
Median target enrolment is 49 among the 85 trials that report a genuine target (sentinel values excluded). 52 of those (61.2%) plan for fewer than 100 participants.
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Obsessive - Compulsive Disorder research is mostly interventional.
72 interventional and 14 observational studies make up this index (83.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
86 total, page 1 of 2
Retrospective Analyses of TrakStar Database
Neuronetics
NCT06917339
Physiological Brain Atlas Development
Vanderbilt University Medical Center
NCT00575081
Developing Brain, Impulsivity and Compulsivity
National Institute of Mental Health (NIMH)
NCT04631042
University of Iowa Interventional Psychiatry Service Patient Registry
Mark Niciu
NCT04480918
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
University of Texas at Austin
NCT05467683
Discovering Factors in the Clinical Study Journey of Patients With OCD
Power Life Sciences
NCT05881356
Mechanisms of Exposure Therapy for OCD
Mclean Hospital
NCT06173752
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Baylor College of Medicine
NCT05609916
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Brigham and Women's Hospital
NCT06376734
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Stanford University
NCT05940324
Neural Mechanisms of Response Inhibition Training for OCRD
University of Wisconsin, Milwaukee
NCT05377125
Interpretation Bias as a Mechanism of Treatment Response in OCD
Mclean Hospital
NCT05224414
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
Yale University
NCT04131829
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
Precision Analytic Research Methods in OCD
Icahn School of Medicine at Mount Sinai
NCT07011901
TMS + Exposure Therapy for Pediatric OCD
Bradley Hospital
NCT05931913
Study of Dextromethorphan in OCD and Related Disorders
Stanford University
NCT04899687
Individually Targeted Neuromodulation for Contamination-based OCD
Mclean Hospital
NCT05048251
Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
Adam Frank
NCT07146438
Efficacy of Nitrous Oxide in OCD: Pilot Study
Stanford University
NCT03826693
Pilot Study of RR-HNK in OCD
Carolyn Rodriguez
NCT06575075
MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
Carolyn Rodriguez
NCT05783817
Using Personalized Assessments in the Treatment of Childhood OCD
Johns Hopkins University
NCT06407648
Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
Francisco A Moreno
NCT07347405
Effects of Psilocybin in Obsessive Compulsive Disorder
Johns Hopkins University
NCT05546658
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
University of California, San Francisco
NCT07065669
Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
Stanford University
NCT03918577
Cortical Stimulation to Treat Obsessive Compulsive Disorder
Andrew Moses Lee, MD, PhD
NCT04958096
Personalized DBS for OCD Guided by Stereoencephalography Mapping
Andrew Moses Lee, MD, PhD
NCT06347978
SEEG-Guided DBS for OCD
Casey H. Halpern, M.D.
NCT05623306
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD
Stanford University
NCT05829681
Understanding How Ketamine Brings About Rapid Improvement in OCD
Stanford University
NCT02624596
A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder
University of Chicago
NCT05624528
Effects of Repeated Psilocybin Dosing in OCD
Yale University
NCT05370911
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
Baylor College of Medicine
NCT03459456
Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder
Butler Hospital
NCT00640133
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
Baylor College of Medicine
NCT05467085
Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD)
Baylor College of Medicine
NCT05915741
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
Baylor College of Medicine
NCT04806516
Development of Adaptive Deep Brain Stimulation for OCD
Baylor College of Medicine
NCT04281134
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
Baylor College of Medicine
NCT03457675
Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder
Massachusetts General Hospital
NCT03184454
Clinical Outcomes From NOCD Treatment of Obsessive-Compulsive Disorder Using Exposure and Response Prevention
NOCD
NCT04701372
Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder
Biohaven Pharmaceuticals
NCT04693351
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
Mclean Hospital
NCT02305537
Physiological Brain Atlas Development
Ohio State University
NCT01210534
Predicting Treatment Response in Patients With OCD
University of Sao Paulo
NCT03993535
Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
Vanderbilt University Medical Center
NCT04335175
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
University of South Florida
NCT02028247
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 13 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Obsessive - Compulsive Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obsessive - Compulsive Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obsessive - Compulsive Disorder page
86 registered trials, 30 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 30 Obsessive - Compulsive Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Baylor College of Medicine sponsors the most Obsessive - Compulsive Disorder trials on record, review their full trial history before evaluating a specific study. See Baylor College of Medicine's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obsessive - Compulsive Disorder condition card totals 86 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.