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NCT05048251 · ClinicalTrials.gov registry record · NA
Individually Targeted Neuromodulation for Contamination-based OCD
A NA study of Obsessive - Compulsive Disorder, sponsored by Mclean Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05048251: Recruiting NA study of Obsessive - Compulsive Disorder, sponsored by Mclean Hospital.
NCT05048251 is a NA study of Obsessive - Compulsive Disorder that is actively recruiting participants, run by Mclean Hospital. The registered enrollment target is 50 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05048251, a NA study of Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by Mclean Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients regardless of symptom type. In this project, the investigators propose to investigate whether a novel method of transcranial magnetic stimulation specifically reduces contamination/washing symptoms - one of the most common types of OCD.
Primary Outcome
Change in functional connectivity between: 1) R MFG and right temporoparietal junction (R TPJ); 2) R MFG and left temporoparietal junction (L TPJ); 3) R MFG and right inferior frontal gyrus (R IFG); 4) R MFG and left inferior frontal gyrus (L IFG); 5) R MFG and right anterior insula (R AI); 6) R MFG and left anterior insula (L AI); 7) R MFG and right posteromedial putamen; and 8) R MFG and left posteromedial putamen
Conditions Studied
Interventions
- DEVICE iTBS
- DEVICE cTBS
- DEVICE sham
Study Locations (1)
Massachusetts
- McLean Hospital - Belmont
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-07-01 |
| Est. Completion | 2024-06-30 |
| Phase | NA |
What NCT05048251 shows while recruiting
NCT05048251 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 3 interventions - of which iTBS is the first listed.
NCT05048251 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05048251 about?
NCT05048251 is a clinical study titled "Individually Targeted Neuromodulation for Contamination-based OCD". Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients regardless of symptom type. In this project, the investigators propose t...
What is the current status of trial NCT05048251?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2022-07-01. Estimated completion is 2024-06-30.
What conditions does trial NCT05048251 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT05048251?
The interventions under investigation include: iTBS (DEVICE), cTBS (DEVICE), sham (DEVICE).
Who is sponsoring clinical trial NCT05048251?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05048251 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05048251's enrollment target sits among peer trials
50 42nd of 84 higher than 43 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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