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ClinicalTrials.gov 30 recruiting now official registry

Obsessive - Compulsive Disorder clinical trials

30 of 86 indexed Obsessive - Compulsive Disorder trials are currently recruiting.

86 US clinical trials · 30 currently recruiting

Obsessive - Compulsive Disorder is the subject of 86 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.

The research picture

Obsessive - Compulsive Disorder has 86 registered US clinical trials, 30 of them open to new participants right now, about 35% of the total.

30
recruiting participants now
35%
of trials open to enrollment
10
in Phase 3–4 (later-stage)
7
top sponsor: Baylor College of Medicine
Phase 16Phase 213Phase 36Phase 44

Active & Recent Trials

86 total, page 2 of 2

COMPLETED NA 203 participants

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

Rebecca Price

NCT04580043

COMPLETED NA 158 participants

Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy

University of Texas at Austin

NCT04663672

COMPLETED 145 participants

Cortical Excitability in Obsessive-Compulsive and Related Disorders

National Institute of Mental Health (NIMH)

NCT00029068

COMPLETED NA 136 participants

Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder

New York State Psychiatric Institute

NCT00045903

COMPLETED Phase 3 127 participants

Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder

Rhode Island Hospital

NCT00533806

COMPLETED Phase 3 124 participants

Treatment of Obsessive Compulsive Disorder in Children

Duke University

NCT00074815

COMPLETED NA 119 participants

Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

University of California, Los Angeles

NCT00748761

COMPLETED NA 105 participants

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

VA Office of Research and Development

NCT01947647

COMPLETED NA 78 participants

Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study

University of Pittsburgh

NCT03265015

COMPLETED Phase 4 74 participants

Treatment of Obsessive-Compulsive Disorder

University of Florida

NCT00000373

COMPLETED 71 participants

Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic

University of Florida

NCT02855580

COMPLETED NA 64 participants

Cognitive Bias Modification for OCD

Mclean Hospital

NCT03799419

COMPLETED NA 63 participants

Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study

University of Miami

NCT06470893

COMPLETED NA 54 participants

Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder

Massachusetts General Hospital

NCT02467374

COMPLETED NA 48 participants

Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder

Boston University Charles River Campus

NCT01414023

COMPLETED NA 46 participants

CBT for Pediatric OCD: Community Training Pilot

Rhode Island Hospital

NCT02202915

COMPLETED Phase 2 45 participants

Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

University of South Florida

NCT01178385

COMPLETED NA 40 participants

Methods for Managing Intrusive Thoughts

University of North Carolina, Chapel Hill

NCT03416504

COMPLETED NA 40 participants

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

Mayo Clinic

NCT02713516

COMPLETED Phase 3 38 participants

Family Based Treatment of Early Childhood Obsessive Compulsive Disorder

Rhode Island Hospital

NCT00055068

COMPLETED Phase 2 34 participants

Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder

University of South Florida

NCT00632229

COMPLETED NA 34 participants

Stepped Care for Treating Obsessive-Compulsive Disorder

Hartford Hospital

NCT00316355

COMPLETED Phase 2 31 participants

Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

University of South Florida

NCT00881465

COMPLETED 30 participants

Serotonin Transporters in Obsessive-Compulsive-Related Disorders

National Institute of Mental Health (NIMH)

NCT00082550

COMPLETED Phase 1 30 participants

Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder

New York State Psychiatric Institute

NCT00316316

COMPLETED Phase 4 30 participants

Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)

Massachusetts General Hospital

NCT00116532

COMPLETED NA 27 participants

Randomized Controlled Trial of Standard ERP and OC-Go

University of California, Los Angeles

NCT03601312

COMPLETED NA 26 participants

Enhancement of Therapeutic Learning in OCD Using tDCS

Yale University

NCT03572543

COMPLETED Phase 2 25 participants

An Open-Label Study Of Lamictal In Neurotic Excoriation

University of Minnesota

NCT00269594

COMPLETED Phase 3 17 participants

Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder

University of California, Los Angeles

NCT00674219

COMPLETED NA 16 participants

D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD

New York State Psychiatric Institute

NCT01172873

COMPLETED Phase 2 12 participants

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

New York State Psychiatric Institute

NCT00956085

COMPLETED NA 11 participants

Personalized Computerized Inhibitory Control Training for OCD

New York State Psychiatric Institute

NCT02378896

COMPLETED Phase 2 9 participants

Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)

New York State Psychiatric Institute

NCT00728923

COMPLETED NA 7 participants

TMS for Improving Response Inhibition in Adolescents With OCD

Bradley Hospital

NCT05104697

COMPLETED Phase 3

Treatment of Obsessive-Compulsive Disorder (OCD) in Children

University of Pennsylvania

NCT00000384

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 13
Phase 3 6
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Obsessive - Compulsive Disorder Trial Landscape

86 indexed Obsessive - Compulsive Disorder studies · 30 recruiting (35%).

Phase mix: 10 late (III/IV) vs 19 early (I/II).

Top sponsor: Baylor College of Medicine (7 trials), 9 others listed. 36 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Obsessive - Compulsive Disorder?

PlainTrial tracks 86 US clinical trials for Obsessive - Compulsive Disorder, of which 30 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obsessive - Compulsive Disorder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.