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Obsessive - Compulsive Disorder clinical trials
30 of 86 indexed Obsessive - Compulsive Disorder trials are currently recruiting.
86 US clinical trials · 30 currently recruiting
Obsessive - Compulsive Disorder is the subject of 86 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.
The research picture
Obsessive - Compulsive Disorder has 86 registered US clinical trials, 30 of them open to new participants right now, about 35% of the total.
- 30
- recruiting participants now
- 35%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 7
- top sponsor: Baylor College of Medicine
Active & Recent Trials
86 total, page 2 of 2
Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors
Rebecca Price
NCT04580043
Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy
University of Texas at Austin
NCT04663672
Cortical Excitability in Obsessive-Compulsive and Related Disorders
National Institute of Mental Health (NIMH)
NCT00029068
Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder
New York State Psychiatric Institute
NCT00045903
Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder
Rhode Island Hospital
NCT00533806
Treatment of Obsessive Compulsive Disorder in Children
Duke University
NCT00074815
Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
University of California, Los Angeles
NCT00748761
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
VA Office of Research and Development
NCT01947647
Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study
University of Pittsburgh
NCT03265015
Treatment of Obsessive-Compulsive Disorder
University of Florida
NCT00000373
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
University of Florida
NCT02855580
Cognitive Bias Modification for OCD
Mclean Hospital
NCT03799419
Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study
University of Miami
NCT06470893
Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
Massachusetts General Hospital
NCT02467374
Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder
Boston University Charles River Campus
NCT01414023
CBT for Pediatric OCD: Community Training Pilot
Rhode Island Hospital
NCT02202915
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
University of South Florida
NCT01178385
Methods for Managing Intrusive Thoughts
University of North Carolina, Chapel Hill
NCT03416504
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Mayo Clinic
NCT02713516
Family Based Treatment of Early Childhood Obsessive Compulsive Disorder
Rhode Island Hospital
NCT00055068
Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
University of South Florida
NCT00632229
Stepped Care for Treating Obsessive-Compulsive Disorder
Hartford Hospital
NCT00316355
Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
University of South Florida
NCT00881465
Serotonin Transporters in Obsessive-Compulsive-Related Disorders
National Institute of Mental Health (NIMH)
NCT00082550
Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder
New York State Psychiatric Institute
NCT00316316
Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)
Massachusetts General Hospital
NCT00116532
Randomized Controlled Trial of Standard ERP and OC-Go
University of California, Los Angeles
NCT03601312
Enhancement of Therapeutic Learning in OCD Using tDCS
Yale University
NCT03572543
An Open-Label Study Of Lamictal In Neurotic Excoriation
University of Minnesota
NCT00269594
Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder
University of California, Los Angeles
NCT00674219
D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD
New York State Psychiatric Institute
NCT01172873
Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder
New York State Psychiatric Institute
NCT00956085
Personalized Computerized Inhibitory Control Training for OCD
New York State Psychiatric Institute
NCT02378896
Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)
New York State Psychiatric Institute
NCT00728923
TMS for Improving Response Inhibition in Adolescents With OCD
Bradley Hospital
NCT05104697
Treatment of Obsessive-Compulsive Disorder (OCD) in Children
University of Pennsylvania
NCT00000384
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 13 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Obsessive - Compulsive Disorder Trial Landscape
86 indexed Obsessive - Compulsive Disorder studies · 30 recruiting (35%).
Phase mix: 10 late (III/IV) vs 19 early (I/II).
Top sponsor: Baylor College of Medicine (7 trials), 9 others listed. 36 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Obsessive - Compulsive Disorder?
PlainTrial tracks 86 US clinical trials for Obsessive - Compulsive Disorder, of which 30 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obsessive - Compulsive Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.