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ClinicalTrials.gov 30 recruiting now early-phase tilt

Obsessive - Compulsive Disorder: early-phase trial registry

30 of 86 indexed Obsessive - Compulsive Disorder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #160 of 28,707 conditions by registered trial count.

86 US clinical trials · 30 currently recruiting · #160 of 28,707 conditions by registered trial count

Obsessive - Compulsive Disorder: 86 US clinical trials tracked, 30 recruiting.

Obsessive - Compulsive Disorder is the subject of 86 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.

Enrollment posture brief

Registry condition obsessive-compulsive-disorder

OPEN 30 | RECR 35% | LATE 10 | EARLY 19 | RANK #160 | SPON 7

Nearest open-share peer: Hemophilia A (35% recruiting · 43 trials)

Alcohol Drinking47.7%Urothelial Carcinoma43%Obsessive - Compulsive D (th…35%COPD32.6%Heart Diseases30.2%
Open-enrollment share among volume-matched conditions near Obsessive - Compulsive Disorder

Obsessive - Compulsive Disorder lists 30 open slots (35% of 86 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Obsessive - Compulsive Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Obsessive - Compulsive Disorder is recruiting below its size-band peers.

    30 of 86 indexed trials (34.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obsessive - Compulsive Disorder trials is spread across many organizations.

    Baylor College of Medicine accounts for 7 of 86 trials (8.1%). 45 distinct sponsors appear on at least one study for this condition label.

  3. Most Obsessive - Compulsive Disorder trials plan to enrol fewer than 100 people.

    Median target enrolment is 49 among the 85 trials that report a genuine target (sentinel values excluded). 52 of those (61.2%) plan for fewer than 100 participants.

  4. Obsessive - Compulsive Disorder research is mostly interventional.

    72 interventional and 14 observational studies make up this index (83.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 213Phase 36Phase 44

Open and recent trials

86 total, page 2 of 2

COMPLETED NA 203 participants

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

Rebecca Price

NCT04580043

COMPLETED NA 158 participants

Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy

University of Texas at Austin

NCT04663672

COMPLETED 145 participants

Cortical Excitability in Obsessive-Compulsive and Related Disorders

National Institute of Mental Health (NIMH)

NCT00029068

COMPLETED NA 136 participants

Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder

New York State Psychiatric Institute

NCT00045903

COMPLETED Phase 3 127 participants

Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder

Rhode Island Hospital

NCT00533806

COMPLETED Phase 3 124 participants

Treatment of Obsessive Compulsive Disorder in Children

Duke University

NCT00074815

COMPLETED NA 119 participants

Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

University of California, Los Angeles

NCT00748761

COMPLETED NA 105 participants

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

VA Office of Research and Development

NCT01947647

COMPLETED NA 78 participants

Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study

University of Pittsburgh

NCT03265015

COMPLETED Phase 4 74 participants

Treatment of Obsessive-Compulsive Disorder

University of Florida

NCT00000373

COMPLETED 71 participants

Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic

University of Florida

NCT02855580

COMPLETED NA 64 participants

Cognitive Bias Modification for OCD

Mclean Hospital

NCT03799419

COMPLETED NA 63 participants

Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study

University of Miami

NCT06470893

COMPLETED NA 54 participants

Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder

Massachusetts General Hospital

NCT02467374

COMPLETED NA 48 participants

Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder

Boston University Charles River Campus

NCT01414023

COMPLETED NA 46 participants

CBT for Pediatric OCD: Community Training Pilot

Rhode Island Hospital

NCT02202915

COMPLETED Phase 2 45 participants

Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

University of South Florida

NCT01178385

COMPLETED NA 40 participants

Methods for Managing Intrusive Thoughts

University of North Carolina, Chapel Hill

NCT03416504

COMPLETED NA 40 participants

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

Mayo Clinic

NCT02713516

COMPLETED Phase 3 38 participants

Family Based Treatment of Early Childhood Obsessive Compulsive Disorder

Rhode Island Hospital

NCT00055068

COMPLETED Phase 2 34 participants

Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder

University of South Florida

NCT00632229

COMPLETED NA 34 participants

Stepped Care for Treating Obsessive-Compulsive Disorder

Hartford Hospital

NCT00316355

COMPLETED Phase 2 31 participants

Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

University of South Florida

NCT00881465

COMPLETED 30 participants

Serotonin Transporters in Obsessive-Compulsive-Related Disorders

National Institute of Mental Health (NIMH)

NCT00082550

COMPLETED Phase 1 30 participants

Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder

New York State Psychiatric Institute

NCT00316316

COMPLETED Phase 4 30 participants

Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)

Massachusetts General Hospital

NCT00116532

COMPLETED NA 27 participants

Randomized Controlled Trial of Standard ERP and OC-Go

University of California, Los Angeles

NCT03601312

COMPLETED NA 26 participants

Enhancement of Therapeutic Learning in OCD Using tDCS

Yale University

NCT03572543

COMPLETED Phase 2 25 participants

An Open-Label Study Of Lamictal In Neurotic Excoriation

University of Minnesota

NCT00269594

COMPLETED Phase 3 17 participants

Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder

University of California, Los Angeles

NCT00674219

COMPLETED NA 16 participants

D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD

New York State Psychiatric Institute

NCT01172873

COMPLETED Phase 2 12 participants

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

New York State Psychiatric Institute

NCT00956085

COMPLETED NA 11 participants

Personalized Computerized Inhibitory Control Training for OCD

New York State Psychiatric Institute

NCT02378896

COMPLETED Phase 2 9 participants

Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)

New York State Psychiatric Institute

NCT00728923

COMPLETED NA 7 participants

TMS for Improving Response Inhibition in Adolescents With OCD

Bradley Hospital

NCT05104697

COMPLETED Phase 3

Treatment of Obsessive-Compulsive Disorder (OCD) in Children

University of Pennsylvania

NCT00000384

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 13
Phase 3 6
Phase 4 4

Named interventions

Most-linked intervention names on Obsessive - Compulsive Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
Ketamine Drug
3 trials
Cognitive-behavioral therapy Behavioral
2 trials
Habit Override Practice Behavioral
2 trials
One Month Blinded Discontinuation Period: Other
2 trials
Cognitive bias modification for interpretation bias Behavioral
2 trials
Memantine Drug
2 trials

US sites by state

Facility locations filed on Obsessive - Compulsive Disorder trials. A trial with sites in several states counts in each.

California 21 trials
Massachusetts 15 trials
Pennsylvania 12 trials
Rhode Island 11 trials
Texas 9 trials
Florida 9 trials
New York 8 trials
North Carolina 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Obsessive - Compulsive Disorder page

86 registered trials, 30 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 30 Obsessive - Compulsive Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Baylor College of Medicine sponsors the most Obsessive - Compulsive Disorder trials on record, review their full trial history before evaluating a specific study. See Baylor College of Medicine's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obsessive - Compulsive Disorder condition card totals 86 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.