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NCT05224414 · ClinicalTrials.gov registry record · NA
Interpretation Bias as a Mechanism of Treatment Response in OCD
A NA study of Obsessive - Compulsive Disorder, sponsored by Mclean Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 106
- Enrollment target
- 1
- Study location
NCT05224414: Recruiting NA study of Obsessive - Compulsive Disorder, sponsored by Mclean Hospital.
NCT05224414 is a NA study of Obsessive - Compulsive Disorder that is actively recruiting participants, run by Mclean Hospital. The registered enrollment target is 106 participants, below the 2,063-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05224414, a NA study of Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by Mclean Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 106 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD). CBM-I is a digital intervention designed to directly manipulate interpretation bias through repeated practice on a training task, thereby inducing cognitive changes in a relatively automatic or implicit manner. Specifically, this study will examine the feasibility, acceptability, and clinical outcomes associated with CBM-I. Adults with obsessive compulsive disorder (OCD) will be recruited from a treatment program for this disorder and participants will be randomly assigned to either receive: 1) up to 12 sessions of CBM-I, or or up to 12 sessions of psychoeducation as a control condition.
Primary Outcome
Interviewer-rated measure of OCD symptoms. It is 19 items, with only items 1-10 scored (from 0-4). Total scores range from 0-40, with higher scores reflecting greater severity.
Conditions Studied
Interventions
- BEHAVIORAL Psychoeducation
- BEHAVIORAL Cognitive bias modification for interpretation bias
Study Locations (1)
Massachusetts
- McLean Hospital - Belmont
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 106 participants |
| Start Date | 2022-03-30 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What NCT05224414 shows while recruiting
NCT05224414 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 2,063-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 2 interventions - of which Psychoeducation is the first listed.
NCT05224414 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05224414 about?
NCT05224414 is a clinical study titled "Interpretation Bias as a Mechanism of Treatment Response in OCD". This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD). CBM-I is a digital intervention designed to directly manipulate interpretation bias through repeated pract...
What is the current status of trial NCT05224414?
This trial is currently recruiting. It is a NA study. The enrollment target is 106 participants. The study started on 2022-03-30. Estimated completion is 2026-08-31.
What conditions does trial NCT05224414 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT05224414?
The interventions under investigation include: Psychoeducation (BEHAVIORAL), Cognitive bias modification for interpretation bias (BEHAVIORAL).
Who is sponsoring clinical trial NCT05224414?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05224414 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05224414's enrollment target sits among peer trials
106 29th of 84 higher than 56 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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