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NCT04631042 · ClinicalTrials.gov registry record
Developing Brain, Impulsivity and Compulsivity
A clinical trial of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder, sponsored by National Institute of Mental Health (NIMH).
- Recruiting
- Registry status
- 1,100
- Enrollment target
- 1
- Study location
NCT04631042: Recruiting study of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder, sponsored by National Institute of Mental Health (NIMH).
NCT04631042 is a study of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder that is actively recruiting participants, run by National Institute of Mental Health (NIMH). The registered enrollment target is 1,100 participants, above the 130-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (746% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04631042, a study of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder, is actively recruiting participants, sponsored by National Institute of Mental Health (NIMH).
- RECRUITING
- Registry status
- 1,100 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders. Researchers want to study changes in the brain to learn more about these behaviors. Differences in genes may also play a role. Objective: To learn about genetic \& brain features that explain why levels of impulsivity and compulsivity vary across people. Eligibility: People ages 6 - 80 Design: Participants will be screened with a medical history and medical record review. Participants will talk about their mental and behavioral development. They may discuss topics like drug use and sexual activity. They will complete surveys about their compulsivity and impulsivity. Parents of child participants may also complete these surveys. Participants may take memory, attention, and thinking tests. They may give blood or saliva samples for gene studies and they may give blood to make induced pluripotent stem cells. Participants may have their face and irises photographs taken. Participants may have a magnetic resonance imaging scan. It will take pictures of their brain. The scanner is shaped like a cylinder. Participants will lie on a table that slides in and out of the scanner. A coil will be placed over their head. They will lie still, watch a movie, and play a game. Participants may ask family members to join the study. Researchers are particularly interested in recruiting twin pairs to the study. Participants under age 25 may repeat these tests every 1-2 years until they turn 25 or until the study ends. For those over age 25, participation will last less than 1 month.
Primary Outcome
Age-related change in cortical glutamate levels and its moderation by individual differences in levels of impulsivity and compulsivity.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,100 participants |
| Start Date | 2022-09-30 |
| Est. Completion | 2031-12-31 |
What NCT04631042 shows while recruiting
NCT04631042 is an observational study that tracks outcomes without assigning an intervention. Its 1,100 participants enrollment target places it among the larger protocols in the corpus, above the 130-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (746% higher).
The record links to 5 conditions, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 0 interventions.
NCT04631042 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04631042 about?
NCT04631042 is a clinical study titled "Developing Brain, Impulsivity and Compulsivity". Background: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders. Researchers want to study changes in the brain to learn more about these behaviors...
What is the current status of trial NCT04631042?
This trial is currently recruiting. The enrollment target is 1,100 participants. The study started on 2022-09-30. Estimated completion is 2031-12-31.
What conditions does trial NCT04631042 study?
This clinical trial studies the following conditions: Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Obsessive - Compulsive Disorder, Conduct Disorder, Typical Development.
Who is sponsoring clinical trial NCT04631042?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04631042 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04631042's enrollment target sits among peer trials
1,100 2nd of 224 the highest of 224 other Autism Spectrum Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autism Spectrum Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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