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NCT05467085 · ClinicalTrials.gov registry record · NA
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
A NA study of Obsessive - Compulsive Disorder, sponsored by Baylor College of Medicine.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 3
- Study locations
NCT05467085: Active NA study of Obsessive - Compulsive Disorder, sponsored by Baylor College of Medicine.
NCT05467085 is a NA study of Obsessive - Compulsive Disorder that is active but no longer recruiting, run by Baylor College of Medicine. The registered enrollment target is 20 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05467085, a NA study of Obsessive - Compulsive Disorder, is active but no longer recruiting, sponsored by Baylor College of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 3
- Study locations
Study Summary
This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD). The device used in this study transmits high frequency sound waves to a particular region of the brain called the Ventral Striatum (VS). LIFU is a non-invasive form of stimulation, which can be used to stimulate deep regions of the brain. In this study, the investigators will administer LIFU to activate the VS area of the brain while also observing this brain stimulation with an MRI machine. Other aims of this study include learning more about the patterns of brain activity associated with OCD and seeing if brain activity changes as symptoms of OCD change over time during the two weeks of LIFU stimulation. Participants in this study will be asked to perform computer administered behavioral tasks -- similar to simple computer games -- to examine whether certain features of OCD (e.g., avoidance of feared triggers) change over the course of LIFU stimulation. The treatment phase of this research study is expected to last two weeks with three weekly (total of 6) treatment sessions all carried at the MRI brain imaging center at Baylor College of Medicine. There will be at least one additional screening visit before treatment starts and a series of follow up visits over a six-month period.
Primary Outcome
This outcome measure will utilize the "Likert Scale" to assess the measure.This scale allows subjects to measure their mood, anxiety, and alertness by marking a scale numbered 0 through 4 with 0 being "Not at All" and 4 being "Extremely." This scale includes several items in which the subjects can indicate how they feel (Positive, negative, anxious, energetic, etc.).
Conditions Studied
Interventions
- DEVICE BX Pulsar 1002
Study Locations (3)
Texas
- Baylor College of Medicine - Houston
- MD Anderson - Houston
Massachusetts
- Massachussetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-08-01 |
| Est. Completion | 2026-08-01 |
| Phase | NA |
What the registry record for NCT05467085 still lists
NCT05467085 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 1 intervention - of which BX Pulsar 1002 is the first listed.
NCT05467085 reports a single indexed study location in Texas, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05467085 about?
NCT05467085 is a clinical study titled "Imaging-Guided Low Intensity Focused Ultrasound (LIFU)". This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD). The device used in this study transmits high frequency sound waves to a particular re...
What is the current status of trial NCT05467085?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-08-01. Estimated completion is 2026-08-01.
What conditions does trial NCT05467085 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT05467085?
The interventions under investigation include: BX Pulsar 1002 (DEVICE).
Who is sponsoring clinical trial NCT05467085?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05467085 being conducted?
This trial has 3 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05467085's enrollment target sits among peer trials
20 70th of 84 higher than 15 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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