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Pennsylvania: below-average open trial sites
2,373 of 6,946 in-state trials are recruiting (34%); below the 37% national average by 3 percentage points, with Phase 2 weight.
According to ClinicalTrials.gov-derived indexes, Pennsylvania sits in the top decile of US states by in-state trial count (#6 of 52 states by registered in-state trial count).
Pennsylvania: 6,946 US clinical trials with in-state sites, 2,373 recruiting.
Pennsylvania has 6,946 registered US clinical trials with a study site in-state, 2,373 of them currently recruiting (below the 37% national average by 3 percentage points). 875 of these trials are in Phase 3 (late-stage) and 1,455 in Phase 2. The most frequently studied condition in Pennsylvania is Breast Cancer, with 122 linked trials.
Peer research-density states
Pennsylvania is in the top decile by in-state trial count. Nearest hubs by indexed volume (not open-share twins):
- Illinois (6,854)
- Ohio (6,514)
- Massachusetts (7,667)
- North Carolina (5,625)
- Arizona (5,607)
Ranked from 51 other states with active in-state trials by how close each state's indexed trial count sits to Pennsylvania's.
Below-average open, early-phase tilt
Pennsylvania still shows 2,373 recruiting of 6,946 in-state trials (34% open), but below the 37% national average by 3 percentage points, so archived statuses weigh heavier than the national baseline.
- 34%
- open (below national share)
- 2,373
- still recruiting despite cool share
- 1,455
- Phase 2 rows in this footprint
- 122
- top: Breast Cancer
Recruiting share is below the 37% national average by 3 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Pennsylvania vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
6,946 Top 12% more indexed trials than 88% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Pennsylvania on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pennsylvania open-enrollment share sits below the national baseline.
2,373 of 6,946 in-state trials (34.2%) are recruiting, against 37% nationally (-2.8 percentage points). Counts include every study with at least one recorded site in the state.
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Philadelphia dominates Pennsylvania's trial geography.
Philadelphia lists 3,827 of 6,946 in-state trials (55.1%) across 1,041 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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Breast Cancer is the most-studied condition in Pennsylvania.
122 of 6,946 in-state trials (1.8%) list Breast Cancer. That is a local concentration figure, not a national disease ranking.
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Pennsylvania sponsorship is fragmented across many organizations.
University of Pennsylvania appears on 513 of 6,946 in-state trials (7.4%). Sponsor identity is as filed on ClinicalTrials.gov.
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3,090 Pennsylvania trials carry a completed status.
3,090 of 6,946 (44.5%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 3,090 |
| Recruiting | 2,373 |
| Active | 1,483 |
By Phase
| Phase | Trial count |
|---|---|
| NA | 1,856 |
| Phase 2 | 1,455 |
| Phase 1 | 1,220 |
| Phase 3 | 875 |
| Phase 4 | 326 |
| Early Phase 1 | 94 |
Top Conditions
Top Sponsors
Where trials run in Pennsylvania
Philadelphia carries 3,827 of Pennsylvania's 6,946 indexed trials (55%) across 1,041 named sites, ahead of Pittsburgh at 2,162. 8 cities clear five listed trials, together naming 2,010 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Philadelphia | 3,827 | 1,041 |
| Pittsburgh | 2,162 | 672 |
| Hershey | 369 | 118 |
| Allentown | 110 | 41 |
| Danville | 103 | 17 |
| Duncansville | 95 | 37 |
| Bethlehem | 83 | 47 |
| Lancaster | 72 | 37 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Volume high
Pennsylvania indexes 6,946 in-state trials (p90 by registry volume among 52 states with sites).
Pennsylvania: in-state trial volume sits in the high tercile
Sites spread across 8 cities with five or more listed trials, led by Philadelphia (3,827, 55% of the state total) and Pittsburgh (2,162), together naming 2,010 distinct research locations.
Phase mix: 875 Phase 3 vs 1,455 Phase 2 (early-phase heavy).
Top condition: Breast Cancer (122 trials); top sponsor University of Pennsylvania (513).
high-volume · high-open figures (6,946 trials · 34% open) describe registry geography under the volume high read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Pennsylvania on in-state trial volume
Cross-state peers under the volume high read (high-volume · high-open), not the same-state browse list.
Similar high-volume hubs (± open share)
- Illinois · 6,854 trials · 33% recruiting
- Ohio · 6,514 trials · 35% recruiting
- Massachusetts · 7,667 trials · 35% recruiting
- North Carolina · 5,625 trials · 33% recruiting
- Arizona · 5,607 trials · 30% recruiting
Similar high-open peers (± trial volume)
- Rhode Island · 34% recruiting · 753 trials
- Oklahoma · 34% recruiting · 1,061 trials
- Oregon · 34% recruiting · 1,999 trials
- Michigan · 34% recruiting · 4,790 trials
- Maryland · 34% recruiting · 6,441 trials