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NCT06376734 · ClinicalTrials.gov registry record · Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

A Phase 2 study of Schizophrenia and Major Depressive Disorder, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
Phase 2
Development phase
180
Enrollment target
2
Study locations

NCT06376734 is a Phase 2 study of Schizophrenia and Major Depressive Disorder that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 180 participants, below the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (17% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06376734, a Phase 2 study of Schizophrenia and Major Depressive Disorder, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
Phase 2
Development phase
180 participants
Enrollment target
2
Study locations

Study Summary

Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe. Extensive behavioral testing will be conducted to determine which behaviors are modulated by stimulating which circuits.

Interventions

  • DEVICE Transcranial magnetic stimulation

Study Locations (2)

California

  • Acacia Clinics - Sunnyvale

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2025-01-30
Est. Completion 2030-06-01
Phase Phase 2

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT06376734

The ClinicalTrials.gov registry entry for NCT06376734 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (17% lower). The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Transcranial magnetic stimulation is the first listed.

NCT06376734 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06376734 about?

NCT06376734 is a clinical study titled "Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness". Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe. Extensive behavioral testing will be conducted to determine which behaviors are modulated by stimulating which circuits.

What is the current status of trial NCT06376734?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2025-01-30. Estimated completion is 2030-06-01.

What conditions does trial NCT06376734 study?

This clinical trial studies the following conditions: Schizophrenia, Major Depressive Disorder, Obsessive - Compulsive Disorder, Generalized Anxiety Disorder, Mood Disorders.

What interventions are being tested in trial NCT06376734?

The interventions under investigation include: Transcranial magnetic stimulation (DEVICE).

Who is sponsoring clinical trial NCT06376734?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06376734 being conducted?

This trial has 2 study locations across California, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.