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TMS + Exposure Therapy for Pediatric OCD
NCT05931913 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this clinical trial is to compare different forms of transcranial magnetic stimulation (TMS) for improving the outcomes of Exposure with Response Prevention (ERP) in youth and young adults with Obsessive-Compulsive Disorder (OCD). Researchers will compare three groups: ERP with one of two different active ("real") forms of TMS vs. ERP with sham ("fake") TMS. The main questions this study aims to answer are: 1) whether TMS normalizes functioning in brain circuits that contribute to compulsive behavior, and 2) whether TMS reduces compulsions during ERP. Participants will: * Complete clinical interviews, questionnaires, and computerized tasks * Complete two MRIs (brain scans) * Receive daily TMS followed by ERP for two weeks (10 sessions)
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex
- BEHAVIORAL Exposure with Response Prevention
- DEVICE Transcranial Magnetic Stimulation: Sham
- DEVICE Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area
Study Locations (2)
Minnesota
- University of Minnesota — Minneapolis
Rhode Island
- Emma Pendleton Bradley Hospital — Riverside
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-03-20 |
| Est. Completion | 2026-07-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05931913
The ClinicalTrials.gov registry entry for NCT05931913 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bradley Hospital, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Obsessive-Compulsive Disorder appearing as the primary indexed condition, and to 4 interventions — of which Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05931913 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Minnesota, Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05931913 about?
NCT05931913 is a clinical study titled "TMS + Exposure Therapy for Pediatric OCD". The goal of this clinical trial is to compare different forms of transcranial magnetic stimulation (TMS) for improving the outcomes of Exposure with Response Prevention (ERP) in youth and young adults with Obsessive-Compulsive Disorder (OCD). Researchers will compare three groups: ERP with one of tw...
What is the current status of trial NCT05931913?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-03-20. Estimated completion is 2026-07-31.
What conditions does trial NCT05931913 study?
This clinical trial studies the following conditions: Obsessive-Compulsive Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05931913?
The interventions under investigation include: Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex (DEVICE), Exposure with Response Prevention (BEHAVIORAL), Transcranial Magnetic Stimulation: Sham (DEVICE), Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05931913?
This trial is sponsored by Bradley Hospital, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05931913 being conducted?
This trial has 2 study locations across Minnesota, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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